Final

Front 1

Histoplasmosis

Back 1

-Primary Pathogen: Infect by Inhalation of Spores
-Histoplasma capsulata
-found in many parts of the world
-dimorphic fungus
-mold grows in soil (bird and bat feces) and inhaled spores convert to yeast in host
-primarily infect lungs (resembles TB)

Front 2

Blastomycosis

Back 2

-Primary Pathogen: Infect by Inhalation of Spores
-Blastomyces dermatitidis
-Southeastern US
-fungus grows in soil, rotting wood, bird droppings (spores inhaled)
-localized disseminated infection
-symptoms resemble TB

Front 3

Coccidiomycosis

Back 3

-Primary Pathogen: Infect by Inhalation of Spores
-Coccidiodies immitis "Valley Fever"
-Western and Southwestern US
-usually self-limited upper respiratory tract disease (inhalation of spores)
-form spherules and endospores in host
-can be fatal

Front 4

Paracoccidiomycosis

Back 4

-Primary Pathogen: Infect by Inhalation of Spores
-Paracoccidioides brasiliensis
-South America
-fungus grows in soil
-infects oral mucous membranes
-can be lethal

Front 5

Aspergillosis

Back 5

-Opportunistic Fungi
-Aspergillus fumigatus
-found everywhere (decaying vegetation)
-causes a number of diseases in the previously healthy and the immunosuppressed

Front 6

Cryptococcosis

Back 6

-Cryptococcus neoformans
-yeast with thick carbohydrate capsule
-occurs widely in nature (pigeon feces)
-infection form inhaled fungal particles
-immunosuppressed

Front 7

Candidiasis

Back 7

-yeast: normal flora
-healthy: oral and vaginal thrush
-immunocompromised: infections of GI, urinary tract, or blood; or life-threatening systemic infections

Front 8

Pneumocystis

Back 8

-Pneumocystis carinii
-intracellular parasite
-in wild and domestic animals
-causes pneumonia in immunosuppressed
-cause of death in AIDS patients

Front 9

Griseofulvin

Back 9

-drug for treatment
-interferes with cell division

Front 10

Azoles

Back 10

-drug for treatment
-stops cell membrane synthesis

Front 11

Amphotericin

Back 11

-drug for treatment
-deals with cell membrane permeability

Front 12

5-fluorocytosine

Back 12

-drug for treatment
-interferes with nucleic acid synthesis

Front 13

Yeast

Back 13

-unicellular
-facultative anaerobe
-reproduce by budding (pseudophypae: incomplete budding)
-usually by contact)

Front 14

Mold

Back 14

-multicellular
-aerobic
-branching hyphae
-vegetative mycelium (for nutrition)
-reproductive mycelium (form spores)
-inhalation or spores or inoculation