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55 Cards in this Set
- Front
- Back
ovaries are covered by
|
mesothelium (modified peritoneum)
|
|
ovarian carcinomas of epithelial origin result from the
|
high regenerative capability of the mesothelium surrounding the ovaries
|
|
dense CT that comprises the outermost layer of the ovarian cortex is called the
|
tunica albuginea
|
|
number of primordial follicles present at birth
|
400,000
|
|
primordial follicles are composed of (2)
|
primary oocyte (arrested in the first meiotic division) surrounded by
squamous follicular cells (renamed granulosa cells in primary and secondary follicles) |
|
squamous follicular cells synthesize and secrete
|
meiotic inhibitory factor (ensures arrest of primary oocyte in the first meiotic division)
|
|
follicle growth and maturation sequence
|
primordial follicle --> unilaminar primary follicle --> multilaminar primary (preantral) follicle --> secondary (antral) follicle --> graafian follcile --> corpus luteum --> corpus albicans
|
|
____ separates the oocyte from the granulosa cells in primary and secondary follicles
|
zona pellucida (perforations in the zone pellucida allow the filopodia of granulosa cells to maintain contact with the microvilli of the oocyte via gap junctions)
|
|
antrum of secondary (antral) follicle is composed of
|
hyaluronic acid-rich follicular liquid
|
|
with the secondary (antral) follicle, granulosa cells that cluster together to form a small mound is called the
|
cumulus oophorus
|
|
with the secondary (antral) follicle, granulosa cells that cluster around the oocyte are called the
|
corona radiata
|
|
theca folliculi
*location *compositionn |
*location: cortical stroma
*composition: theca interna and externa |
|
theca interna cells secrete _____ and produce ______
|
angiogenic factor (enhances development of blood vessels)
androgens (travel to granulosa cells) |
|
granulosa cells
*respond to *syntheize |
*respond to: FSH
*syntheize: aromatase (converts androgens to estrogen) |
|
functions of theca externa (2)
|
protective barrier
aid in rupturing the graafian follicle via contraction of smooth muscle |
|
ovaries are covered by
|
mesothelium (modified peritoneum)
|
|
ovarian carcinomas of epithelial origin result from the
|
high regenerative capability of the mesothelium surrounding the ovaries
|
|
dense CT that comprises the outermost layer of the ovarian cortex is called the
|
tunica albuginea
|
|
number of primordial follicles present at birth
|
400,000
|
|
primordial follicles are composed of (2)
|
primary oocyte (arrested in the first meiotic division) surrounded by
squamous follicular cells (renamed granulosa cells in primary and secondary follicles) |
|
squamous follicular cells synthesize and secrete
|
meiotic inhibitory factor (ensures arrest of primary oocyte in the first meiotic division)
|
|
follicle growth and maturation sequence
|
primordial follicle --> unilaminar primary follicle --> multilaminar primary (preantral) follicle --> secondary (antral) follicle --> graafian follcile --> corpus luteum --> corpus albicans
|
|
____ separates the oocyte from the granulosa cells in primary and secondary follicles
|
zona pellucida (perforations in the zone pellucida allow the filopodia of granulosa cells to maintain contact with the microvilli of the oocyte via gap junctions)
|
|
antrum of secondary (antral) follicle is composed of
|
hyaluronic acid-rich follicular liquid
|
|
with the secondary (antral) follicle, granulosa cells that cluster together to form a small mound is called the
|
cumulus oophorus
|
|
with the secondary (antral) follicle, granulosa cells that cluster around the oocyte are called the
|
corona radiata
|
|
theca folliculi
*location *compositionn |
*location: cortical stroma
*composition: theca interna and externa |
|
theca interna cells secrete _____ and produce ______
|
angiogenic factor (enhances development of blood vessels)
androgens (travel to granulosa cells) |
|
granulosa cells
*respond to *syntheize |
*respond to: FSH
*syntheize: aromatase (converts androgens to estrogen) |
|
function of theca externa
|
protective barrier
|
|
ovaries are covered by
|
mesothelium (modified peritoneum)
|
|
ovarian carcinomas of epithelial origin result from the
|
high regenerative capability of the mesothelium surrounding the ovaries
|
|
dense CT that comprises the outermost layer of the ovarian cortex is called the
|
tunica albuginea
|
|
number of primordial follicles present at birth
|
400,000
|
|
primordial follicles are composed of (2)
|
primary oocyte (arrested in the first meiotic division) surrounded by
squamous follicular cells (renamed granulosa cells in primary and secondary follicles) |
|
squamous follicular cells synthesize and secrete
|
meiotic inhibitory factor (ensures arrest of primary oocyte in the first meiotic division)
|
|
follicle growth and maturation sequence
|
primordial follicle --> unilaminar primary follicle --> multilaminar primary (preantral) follicle --> secondary (antral) follicle --> graafian follcile --> corpus luteum --> corpus albicans
|
|
____ separates the oocyte from the granulosa cells in primary and secondary follicles
|
zona pellucida (perforations in the zone pellucida allow the filopodia of granulosa cells to maintain contact with the microvilli of the oocyte via gap junctions)
|
|
antrum of secondary (antral) follicle is composed of
|
hyaluronic acid-rich follicular liquid
|
|
with the secondary (antral) follicle, granulosa cells that cluster together to form a small mound is called the
|
cumulus oophorus
|
|
with the secondary (antral) follicle, granulosa cells that cluster around the oocyte are called the
|
corona radiata
|
|
theca folliculi
*location *compositionn |
*location: cortical stroma
*composition: theca interna and externa |
|
theca interna cells secrete _____ and produce ______
|
angiogenic factor (enhances development of blood vessels)
androgens (travel to granulosa cells) |
|
granulosa cells
*respond to *syntheize |
*respond to: FSH
*syntheize: aromatase (converts androgens to estrogen) |
|
function of theca externa
|
protective barrier
|
|
the one large "dominant" follicle that undergoes ovulation is called the
|
graafian follicle
|
|
the visible transparent protuberance on the surface of the ovary made by the graafian follicle is known as the
|
stigma
|
|
substances that weaken the wall of the follicle and erode the tunica albuginea during ovulation (4)
|
collagenase
histamine prostaglandins vasopressin |
|
in reponse to LH ____ cells and _____ cells undergo luteinization
|
theca cells
granuloa cells |
|
endometrium (uterine mucosa) is maintained by the presence of
|
progesterone (produced by the corpus luteum)
|
|
number of primordial follicles that mature to the point of ovulation
|
400
|
|
times when atresia is intensified (3)
|
at birth
during puberty following parturition *times of fluctuation in hormone levels* |
|
atresia is characterized by
|
apoptosis of granulosa cells (slough into the antrum)
|
|
during atresia, the basement membrane becomes thickened and prominent and folds upon itself to form a small, irregular firbous scar known as the
|
corpus fibrosum
|
|
in young girls approaching menarche, associated thecal cells remain viable and form a(n)
|
interstitial gland (produces estrogen)
|