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55 Cards in this Set

  • Front
  • Back
ovaries are covered by
mesothelium (modified peritoneum)
ovarian carcinomas of epithelial origin result from the
high regenerative capability of the mesothelium surrounding the ovaries
dense CT that comprises the outermost layer of the ovarian cortex is called the
tunica albuginea
number of primordial follicles present at birth
400,000
primordial follicles are composed of (2)
primary oocyte (arrested in the first meiotic division) surrounded by

squamous follicular cells (renamed granulosa cells in primary and secondary follicles)
squamous follicular cells synthesize and secrete
meiotic inhibitory factor (ensures arrest of primary oocyte in the first meiotic division)
follicle growth and maturation sequence
primordial follicle --> unilaminar primary follicle --> multilaminar primary (preantral) follicle --> secondary (antral) follicle --> graafian follcile --> corpus luteum --> corpus albicans
____ separates the oocyte from the granulosa cells in primary and secondary follicles
zona pellucida (perforations in the zone pellucida allow the filopodia of granulosa cells to maintain contact with the microvilli of the oocyte via gap junctions)
antrum of secondary (antral) follicle is composed of
hyaluronic acid-rich follicular liquid
with the secondary (antral) follicle, granulosa cells that cluster together to form a small mound is called the
cumulus oophorus
with the secondary (antral) follicle, granulosa cells that cluster around the oocyte are called the
corona radiata
theca folliculi

*location
*compositionn
*location: cortical stroma

*composition: theca interna and externa
theca interna cells secrete _____ and produce ______
angiogenic factor (enhances development of blood vessels)

androgens (travel to granulosa cells)
granulosa cells

*respond to
*syntheize
*respond to: FSH
*syntheize: aromatase (converts androgens to estrogen)
functions of theca externa (2)
protective barrier

aid in rupturing the graafian follicle via contraction of smooth muscle
ovaries are covered by
mesothelium (modified peritoneum)
ovarian carcinomas of epithelial origin result from the
high regenerative capability of the mesothelium surrounding the ovaries
dense CT that comprises the outermost layer of the ovarian cortex is called the
tunica albuginea
number of primordial follicles present at birth
400,000
primordial follicles are composed of (2)
primary oocyte (arrested in the first meiotic division) surrounded by

squamous follicular cells (renamed granulosa cells in primary and secondary follicles)
squamous follicular cells synthesize and secrete
meiotic inhibitory factor (ensures arrest of primary oocyte in the first meiotic division)
follicle growth and maturation sequence
primordial follicle --> unilaminar primary follicle --> multilaminar primary (preantral) follicle --> secondary (antral) follicle --> graafian follcile --> corpus luteum --> corpus albicans
____ separates the oocyte from the granulosa cells in primary and secondary follicles
zona pellucida (perforations in the zone pellucida allow the filopodia of granulosa cells to maintain contact with the microvilli of the oocyte via gap junctions)
antrum of secondary (antral) follicle is composed of
hyaluronic acid-rich follicular liquid
with the secondary (antral) follicle, granulosa cells that cluster together to form a small mound is called the
cumulus oophorus
with the secondary (antral) follicle, granulosa cells that cluster around the oocyte are called the
corona radiata
theca folliculi

*location
*compositionn
*location: cortical stroma

*composition: theca interna and externa
theca interna cells secrete _____ and produce ______
angiogenic factor (enhances development of blood vessels)

androgens (travel to granulosa cells)
granulosa cells

*respond to
*syntheize
*respond to: FSH
*syntheize: aromatase (converts androgens to estrogen)
function of theca externa
protective barrier
ovaries are covered by
mesothelium (modified peritoneum)
ovarian carcinomas of epithelial origin result from the
high regenerative capability of the mesothelium surrounding the ovaries
dense CT that comprises the outermost layer of the ovarian cortex is called the
tunica albuginea
number of primordial follicles present at birth
400,000
primordial follicles are composed of (2)
primary oocyte (arrested in the first meiotic division) surrounded by

squamous follicular cells (renamed granulosa cells in primary and secondary follicles)
squamous follicular cells synthesize and secrete
meiotic inhibitory factor (ensures arrest of primary oocyte in the first meiotic division)
follicle growth and maturation sequence
primordial follicle --> unilaminar primary follicle --> multilaminar primary (preantral) follicle --> secondary (antral) follicle --> graafian follcile --> corpus luteum --> corpus albicans
____ separates the oocyte from the granulosa cells in primary and secondary follicles
zona pellucida (perforations in the zone pellucida allow the filopodia of granulosa cells to maintain contact with the microvilli of the oocyte via gap junctions)
antrum of secondary (antral) follicle is composed of
hyaluronic acid-rich follicular liquid
with the secondary (antral) follicle, granulosa cells that cluster together to form a small mound is called the
cumulus oophorus
with the secondary (antral) follicle, granulosa cells that cluster around the oocyte are called the
corona radiata
theca folliculi

*location
*compositionn
*location: cortical stroma

*composition: theca interna and externa
theca interna cells secrete _____ and produce ______
angiogenic factor (enhances development of blood vessels)

androgens (travel to granulosa cells)
granulosa cells

*respond to
*syntheize
*respond to: FSH
*syntheize: aromatase (converts androgens to estrogen)
function of theca externa
protective barrier
the one large "dominant" follicle that undergoes ovulation is called the
graafian follicle
the visible transparent protuberance on the surface of the ovary made by the graafian follicle is known as the
stigma
substances that weaken the wall of the follicle and erode the tunica albuginea during ovulation (4)
collagenase

histamine

prostaglandins

vasopressin
in reponse to LH ____ cells and _____ cells undergo luteinization
theca cells

granuloa cells
endometrium (uterine mucosa) is maintained by the presence of
progesterone (produced by the corpus luteum)
number of primordial follicles that mature to the point of ovulation
400
times when atresia is intensified (3)
at birth

during puberty

following parturition

*times of fluctuation in hormone levels*
atresia is characterized by
apoptosis of granulosa cells (slough into the antrum)
during atresia, the basement membrane becomes thickened and prominent and folds upon itself to form a small, irregular firbous scar known as the
corpus fibrosum
in young girls approaching menarche, associated thecal cells remain viable and form a(n)
interstitial gland (produces estrogen)