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30 Cards in this Set

  • Front
  • Back
Type I Hyperlipidemia
Name and Pathophysiology?
Hyperchylomicronemia
Lipoprotein liase deficiency or altered apolipoprotein CII
Type I Hyperlipidemia
Lipid abnormality?
Increased triglycerides
Type I Hyperlipidemia
Lipoprotein abnormality?
Increased Chylomicrons
Type I Hyperlipidemia
Clinical Manifestations?
Pancreatitis
Eruptive xanthomas
Lipemia retinalis
Type I Hyperlipidemia
Therapy?
Fat Free Diet
Type IIa Hyperlipidemia
Name and Pathophysiology?
Hypercholesterolemia
LDL receptor deficiency
Type IIa Hyperlipidemia
Lipid abnormality?
Increased cholesterol
Type IIa Hyperlipidemia
Lipoprotein abnormality?
Increased LDL
Type IIa Hyperlipidemia
Clinical Manifestations?
CAD
Tendon xanthomas
Xanthelasma
Type IIa Hyperlipidemia
Therapy?
Restricted diet
Bile acid-binding resins
Statins
Nicotinic acid
Type IIb Hyperlipidemia
Name and Pathophysiology?
Combined hyperlipidemia
Increased hepatic synthesis of VLDL or Increased apoB
Type IIb Hyperlipidemia
Lipid abnormality?
Increased cholesterol and triglycerides
Type IIb Hyperlipidemia
Lipoprotein abnormality?
Increased LDL and VLDLD
Type IIb Hyperlipidemia
Clinical Manifestations?
CAD
Type IIb Hyperlipidemia
Therapy?
Restricted diet
Bile acid binding resins
Nicotinic acid
Gemfibrozil
Statins
Type III Hyperlipidemia
Name and Pathophysiology?
Dysbetalipoproteinemia
Type III Hyperlipidemia
Lipid Abnormality?
Increased triglycerides and cholesterol
Type III Hyperlipidemia
Lipoprotein Abnormality?
Increased VLDL and ILDL
Type III Hyperlipidemia
Clincal Manifestations?
Palmar fatty streaks
Tuberous xanthomas
CAD
Peripheral vascular disease
Hypothyroidism
Type III Hyperlipidemia
Therapy?
Gemfibrozil
Type IV Hyperlipidemia
Name and Pathophysiology?
Hypertriglyceridemia
Type IV Hyperlipidemia
Lipid Abnormality?
Increased triglycerides
Type IV Hyperlipidemia
Lipoprotein Abnormality?
Increased VLDL
Type IV Hyperlipidemia
Clincal Manifestations?
Eruptive xanthomas
Pancreatitis
Diabetes
+/- CAD
Type IV Hyperlipidemia
Therapy?
Restricted diet
Gemfibrozil
Type V Hyperlipidemia
Name and Pathophysiology?
Mixed hypertriglyceridemia
Type V Hyperlipidemia
Lipid Abnormality?
Triglycerides increased
Type V Hyperlipidemia
Lipoprotein Abnormality?
Increased VLDL and Chylomicrons
Type V Hyperlipidemia
Clincal Manifestations?
Eruptive xanthomas
Pancreatitis
Diabetes
+/- CAD
Type V Hyperlipidemia
Therapy?
Restricted diet
Gemfibrozil