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7 Cards in this Set

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Explain the role of the hormones insulin and glucagon in the regulation of blood glucose
1. (When blood glucose rises (hyperglycemia)- like after a meal)
- Insulin (from the pancreas, targets liver, muscle, adipose tissue)--> glucose is cleared from the blood and glycogen is created.

2. (When blood glucose falls (hypoglycemia) like after exercising)
- Gluagon (from pancreas, targets liver-->Glycogen breakdown=increased blood glucose in blood stream-->Hyperglycemia. Glucagon increases blood glucose level
What is the normal range of blood glucose in humans?
70-100mg/dL
- liver is responsible for maintaining this
Describe diabetes mellitus type 1
Autoimmune attack on the pancreas. Complete failure of blood glucose regulations. Autoimmun reaction occurs-->attacks beta cells in pancreas that make insulin-->pancreas looses ability to produce insulin=results in elevated levels of blood glucose. Insulin must be injected for life. Strong genetic predisposition. Insulin producing cells in pancreas are destroyed
Describe diabetes mellitus type 2
Progressive disease. Characterized by insulin resistance. Insulin production is not inhibited, but ability for body to respond to insulin is affected-->eventually amount of insulin produced from pancreas leads to high blood glucose. Insluin production may be low, normal, or high
What are the diet management approaches to diabetes type 1?
- Insulin injections.
- Diet must be coordinated with insulin-must regulate intake of carbohydrates.
- Exchange system/Carbohydrate counting (through diabetic exchange system)
- regular meals and 1 or more snacks as well as a well regulation of CHO:Protein:Fat to maximize swings in blood glucose
- Diet should include ample fiber
-Supply energy in balance with expenditure
- Low in sat. fats and cholesterol
hat are the diet management approaches to diabetes type 2?
Weight loss can reduce risk or help manage
What are the complications of diabetes? (7)
1. Leading cuase of kidney disease (nephropathy)
2. 60-70% of diabetics have mild to severe nerve damage (neuropathy)= diabetes is leaing cause of amputations, can affect bladder control
3. Leading cause of blindness-glucose can affect capillaries in eye
4. Hypertension in 60-70% of diabetics
5. 2-4X risk of stroke,
6. faster age decline in cognition
7. 2-4X risk of heart disease. Usually the cause of death with people with diabetes.