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51 Cards in this Set

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1)Risks of ectopic pregnancy are:
2)What are the most helpful investigatory tests for it?
1)Tubal ligation, DES-diethylstillbesterol, tubal pathology, prior ectopic pregnancy.
2)HCG>6500 -> transabd ultrasound next to detect
1)Define endometriosis.
2)S&S
3)gold standard test
1)Endometrial glands and stroma outside the uterine cavity.
2)May pelvic pain, dyspareunia, infertility, dysmenorrhea, pain on defecation or urination, constip., hematuria, diarrhea
3)laparoscopy
1)Define Zollinger-Ellison syndrome (an uncommon cause of Peptic Ulcer Disease, PUD)
1)Tumor of the small intestine or pancreas that secrete excessive amounts of gastrin hormone->overproduction of stomach acid
1)What are the main factors of Peptic Ulcer Disease?
2)What is an uncommon cause of PUD?
1)Helicobacter pylori infection and NSAIDs use.
2)Zollinger-Ellison syndrome.
1)A pharmacological diagnostic test for GERD:
1)PPI therapy and positive response to it. NB: pnt w/out endoscopic findings can still have significant symptoms.
1)Tnx of H.pylori
1)Only when H.pylori test is positive: PPI BID (bis in die, lat. twice daily), amox (substitute with metronidazole if pennic.allergies) and clarithromycin. ONLY WHEN TEST IS DOCUMENTED
1)Clinical tests for peritonitis- inflammation of peritoneum, a thin membrane lining abdominal cavity and organs.
1)Pain produced, when pnt is asked to cough. Pain produced on exhalation and inhalation. Clinical test strongly suggests ... when pain in all three instances is reproduced.
1)CT scan will help differentiate following causes of abdominal pain:
1)Appendicitis, diverticulitis, pancreatitis, renal calculi
1)Presentation of renal calculi vs pyelonephritis.
1)flank pain radiating to groin vs non-radiating flank pain.
1)When does pain precede vomiting?
1)In appendicitis.
1)Name diagnostic tests for pancreatitis.
1)Serum lipase and amylase. Contrast CT scan.
What test has a 100% specificity and a 97% sensitivity for diverticulitis? It is also the best imaging study for appendicitis.
Helical CT scan with rectal contrast. Transabdominal ultrasound is the next best study.
Pain awakens the pnt at night and radiates to right scapula. It is often associated with nausea and vomiting. What is it?
Biliary pain (biliary colic)
1)What is Charcot's triad? 2)And what is it for? 3)what diagnostic study is the best?
1)pain, fever, jaundice 2)acute cholangitis (potentially lethal if not treated urgently) 3)ERCP, Endoscopic Retrograde Colangeopancreatography (ultrasound doesn't work at all)
What does cholescintigraphy do?
It studies a gallbladder ejection fraction to diagnose a gallbladder dysfunction, yet not highly predictive.
What is an imaging study of choice for pancreatitis?
A CT scan
What is the most common (up to 70%) cause of bowel obstruction?
Adhesions from a prior surgery
Clinical signs of bowel obstruction are:
increased!!! bowel sounds, distention, previous abdominal surgery, >50yo, vomiting
What is the initial imaging study for bowel obstruction?
X-ray, b/c can show air-fluid level, distention. Even if it is negative, suspicion remains high. Then go with CT or ultrasound.
Poorly localize epigastric or periumbilical pain, guarding, rigidity, rebound tenderness (Rovsing-referred rebound tenderness) is a likely sign of what?
appendicitis
Elevated WBC and CRP (C-reactive protein) may be suggestive of but not rule out if negative...?
appendicitis
What is the best imaging study of appendicitis?
A helical CT with 3% diatrizoate rectal contrast.
Gradual onset of pain in LLQ is suggestive of what?
Diverticulitis. If adjacent to the bladder it may cause increased urinary frequency or urgency.
What is IBS (irritable bowel syndrome)?
A functional disorder characterized by chronic abdominal pain, defecation or change in the frequency or appearance of stool. Spontaneously resolves in 50% pnts.
An in-utero exposure to DES (diethylstilbesterol) may affect a woman in what way?
Predispose to Ectopic Pregnancy later.
1)Hemochromatosis definition.
2)Hemosiderosis
3)What is the best test for them?
1)iron overload. A treatable disease. Liver, heart and endocrine glands are affected the most.
2)Multiple transfusions. 1) and 2) are used synonymously.
3)Transferrin saturation
What are most common liver dxs?
Nonalcoholic fatty liver disease (NAFLD), alcoholic hepatitis, viral hepatitis
1)What pathway is measured by International Normalized Ratio?
2)By aPTT activated Partial Thromboplastin Time?
3)What does PT measure?
1)Extrinsic (INR=PTtest/PTnorm)
2)Intrinsic
3)II, V, VII, X and fibrinogen
Rx to treat medium or large gastroesophageal varices:
non-selective beta blockers: propranolol or nadolol (titrate to 50-60 beats/min at rest), if not tolerated->band ligation
Spontaneous Bacterial Peritonitis -great risk in pnt's with ascites. Treatment and prophylaxis with?
Treatment- IV cephalosporins (D-Ala-Ala attachment and inhibition of proteoglycan crosslinking). Prophylaxis with fluoroquinolones (inhibit DNA gyrase that facilitates DNA unwinding for replication and transcription)
1)Sprue
1)Carbohydrate malabsorption in sm intestine, a mucosal disorder.
What are the primary causes of PUD (Peptic Ulcer Disease)?
Helicobacter pylori and NSAIDs. Zollinger-Ellison syndrome (tumors of sm intestine or pancrease) is a much rarer cause of the disease.
Name a primary diagnostic approach to treating GERD by a primary care physician.
PPI not endoscopy
What test can confirm H. pylori eradication and why?
Stool antigen test, b/c it is Antigen Based not antibody (Ab stays present after eradication)
What are the 'ingredients' of an H. pylori triple therapy?
A PPI, a penicillin based antibiotic (eg amoixicillin. Allergic? -> metronidazole (Flagyl) is used to treat protozoa and anaerobic bacteria), and a macrolide (eg clarithromycin). 14 days -more effective
In presence of slow chronic bleeding what is the most appropriate first step in diagnostic studies?
EGD- esophagogastroduadenoscopy. Also used in suspected UGI bleed. If EGD is negative-> colonoscopy is the next step.
Hematochezia definition
non massive grossly evident bleeding
In evaluation of bleeding how significant is a non tender abdominal examination?
Very significant. Sever diverticular and vascular bleeds are non-tender, non-painful. Pay attention to systolic <115, HR=>100/min. Together with non-tender finding->80% risk of bleed. Urgent colonoscopy
Octreotide (Sandostatin)
inhibits growth hormone, glucagon and insulin potently. Treatment of thymic neoplasms and ESOPHAGEAL VARICES.
What is an infectious organism suggested in consumption of undercooked poultry or employment in poultry industry?
Campylobacter jejuni ->(Guilliam Barre syndrome possible)
What's an infectious organism suggested with recent abics use?
Clostridium difficile (drum stick shaped, anaerobic spore-forming rod). Pseudo membranous colitis.
Community outbreak of gastroenteritis in winter or on cruise ships
Norovirus (single-stranded RNA, non-enveloped, calcivirus)
Daycare attendance or employment
Shigella, Giardia, Cryptosporidium
Seafood caused gastroenteritis or septicemia of open wounds
Vibrio (gram neg, curved rod found in salt water)
Hemolytic Uremic Syndrome or renal failure due to community acquired food borne transmission
E coli O157-H7
Community acquired foodborne transmission due to?
Yersinia, Salmonella, Campylobacter, E.coli O157-H7, enteric viruses (person to person too)
Receptive anal intercourse, oral-anal sex (anilingus) is risky for contraction of?
Giardia and/or Clostridium histolyticum
Shiga toxin producing E coli are afebrile versus (see other side of card)
Salmonella, Campylobacter and Shigella are febrile. All with bloody diarrhea and abd pain
Rx for noninflammatory diarrhea:
Bismuth subsalicylates (Pepto-Bismol or Kaopectate) and loperamide (Immodium)
What does sed rate help reveal?
Inflammatory activity is suggested with this test running positive (red cell falls a certain distance in a tube, the greater the distance, the greater the inflammatory response of the pnt's immune system is)
How do they test for lactoferrin, a neutrophil product (eg. for C. difficile colitis diarrhea)?
Latex agglutination test