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51 Cards in this Set
- Front
- Back
1)Risks of ectopic pregnancy are:
2)What are the most helpful investigatory tests for it? |
1)Tubal ligation, DES-diethylstillbesterol, tubal pathology, prior ectopic pregnancy.
2)HCG>6500 -> transabd ultrasound next to detect |
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1)Define endometriosis.
2)S&S 3)gold standard test |
1)Endometrial glands and stroma outside the uterine cavity.
2)May pelvic pain, dyspareunia, infertility, dysmenorrhea, pain on defecation or urination, constip., hematuria, diarrhea 3)laparoscopy |
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1)Define Zollinger-Ellison syndrome (an uncommon cause of Peptic Ulcer Disease, PUD)
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1)Tumor of the small intestine or pancreas that secrete excessive amounts of gastrin hormone->overproduction of stomach acid
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1)What are the main factors of Peptic Ulcer Disease?
2)What is an uncommon cause of PUD? |
1)Helicobacter pylori infection and NSAIDs use.
2)Zollinger-Ellison syndrome. |
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1)A pharmacological diagnostic test for GERD:
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1)PPI therapy and positive response to it. NB: pnt w/out endoscopic findings can still have significant symptoms.
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1)Tnx of H.pylori
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1)Only when H.pylori test is positive: PPI BID (bis in die, lat. twice daily), amox (substitute with metronidazole if pennic.allergies) and clarithromycin. ONLY WHEN TEST IS DOCUMENTED
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1)Clinical tests for peritonitis- inflammation of peritoneum, a thin membrane lining abdominal cavity and organs.
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1)Pain produced, when pnt is asked to cough. Pain produced on exhalation and inhalation. Clinical test strongly suggests ... when pain in all three instances is reproduced.
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1)CT scan will help differentiate following causes of abdominal pain:
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1)Appendicitis, diverticulitis, pancreatitis, renal calculi
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1)Presentation of renal calculi vs pyelonephritis.
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1)flank pain radiating to groin vs non-radiating flank pain.
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1)When does pain precede vomiting?
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1)In appendicitis.
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1)Name diagnostic tests for pancreatitis.
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1)Serum lipase and amylase. Contrast CT scan.
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What test has a 100% specificity and a 97% sensitivity for diverticulitis? It is also the best imaging study for appendicitis.
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Helical CT scan with rectal contrast. Transabdominal ultrasound is the next best study.
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Pain awakens the pnt at night and radiates to right scapula. It is often associated with nausea and vomiting. What is it?
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Biliary pain (biliary colic)
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1)What is Charcot's triad? 2)And what is it for? 3)what diagnostic study is the best?
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1)pain, fever, jaundice 2)acute cholangitis (potentially lethal if not treated urgently) 3)ERCP, Endoscopic Retrograde Colangeopancreatography (ultrasound doesn't work at all)
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What does cholescintigraphy do?
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It studies a gallbladder ejection fraction to diagnose a gallbladder dysfunction, yet not highly predictive.
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What is an imaging study of choice for pancreatitis?
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A CT scan
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What is the most common (up to 70%) cause of bowel obstruction?
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Adhesions from a prior surgery
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Clinical signs of bowel obstruction are:
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increased!!! bowel sounds, distention, previous abdominal surgery, >50yo, vomiting
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What is the initial imaging study for bowel obstruction?
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X-ray, b/c can show air-fluid level, distention. Even if it is negative, suspicion remains high. Then go with CT or ultrasound.
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Poorly localize epigastric or periumbilical pain, guarding, rigidity, rebound tenderness (Rovsing-referred rebound tenderness) is a likely sign of what?
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appendicitis
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Elevated WBC and CRP (C-reactive protein) may be suggestive of but not rule out if negative...?
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appendicitis
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What is the best imaging study of appendicitis?
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A helical CT with 3% diatrizoate rectal contrast.
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Gradual onset of pain in LLQ is suggestive of what?
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Diverticulitis. If adjacent to the bladder it may cause increased urinary frequency or urgency.
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What is IBS (irritable bowel syndrome)?
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A functional disorder characterized by chronic abdominal pain, defecation or change in the frequency or appearance of stool. Spontaneously resolves in 50% pnts.
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An in-utero exposure to DES (diethylstilbesterol) may affect a woman in what way?
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Predispose to Ectopic Pregnancy later.
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1)Hemochromatosis definition.
2)Hemosiderosis 3)What is the best test for them? |
1)iron overload. A treatable disease. Liver, heart and endocrine glands are affected the most.
2)Multiple transfusions. 1) and 2) are used synonymously. 3)Transferrin saturation |
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What are most common liver dxs?
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Nonalcoholic fatty liver disease (NAFLD), alcoholic hepatitis, viral hepatitis
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1)What pathway is measured by International Normalized Ratio?
2)By aPTT activated Partial Thromboplastin Time? 3)What does PT measure? |
1)Extrinsic (INR=PTtest/PTnorm)
2)Intrinsic 3)II, V, VII, X and fibrinogen |
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Rx to treat medium or large gastroesophageal varices:
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non-selective beta blockers: propranolol or nadolol (titrate to 50-60 beats/min at rest), if not tolerated->band ligation
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Spontaneous Bacterial Peritonitis -great risk in pnt's with ascites. Treatment and prophylaxis with?
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Treatment- IV cephalosporins (D-Ala-Ala attachment and inhibition of proteoglycan crosslinking). Prophylaxis with fluoroquinolones (inhibit DNA gyrase that facilitates DNA unwinding for replication and transcription)
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1)Sprue
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1)Carbohydrate malabsorption in sm intestine, a mucosal disorder.
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What are the primary causes of PUD (Peptic Ulcer Disease)?
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Helicobacter pylori and NSAIDs. Zollinger-Ellison syndrome (tumors of sm intestine or pancrease) is a much rarer cause of the disease.
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Name a primary diagnostic approach to treating GERD by a primary care physician.
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PPI not endoscopy
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What test can confirm H. pylori eradication and why?
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Stool antigen test, b/c it is Antigen Based not antibody (Ab stays present after eradication)
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What are the 'ingredients' of an H. pylori triple therapy?
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A PPI, a penicillin based antibiotic (eg amoixicillin. Allergic? -> metronidazole (Flagyl) is used to treat protozoa and anaerobic bacteria), and a macrolide (eg clarithromycin). 14 days -more effective
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In presence of slow chronic bleeding what is the most appropriate first step in diagnostic studies?
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EGD- esophagogastroduadenoscopy. Also used in suspected UGI bleed. If EGD is negative-> colonoscopy is the next step.
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Hematochezia definition
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non massive grossly evident bleeding
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In evaluation of bleeding how significant is a non tender abdominal examination?
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Very significant. Sever diverticular and vascular bleeds are non-tender, non-painful. Pay attention to systolic <115, HR=>100/min. Together with non-tender finding->80% risk of bleed. Urgent colonoscopy
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Octreotide (Sandostatin)
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inhibits growth hormone, glucagon and insulin potently. Treatment of thymic neoplasms and ESOPHAGEAL VARICES.
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What is an infectious organism suggested in consumption of undercooked poultry or employment in poultry industry?
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Campylobacter jejuni ->(Guilliam Barre syndrome possible)
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What's an infectious organism suggested with recent abics use?
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Clostridium difficile (drum stick shaped, anaerobic spore-forming rod). Pseudo membranous colitis.
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Community outbreak of gastroenteritis in winter or on cruise ships
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Norovirus (single-stranded RNA, non-enveloped, calcivirus)
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Daycare attendance or employment
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Shigella, Giardia, Cryptosporidium
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Seafood caused gastroenteritis or septicemia of open wounds
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Vibrio (gram neg, curved rod found in salt water)
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Hemolytic Uremic Syndrome or renal failure due to community acquired food borne transmission
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E coli O157-H7
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Community acquired foodborne transmission due to?
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Yersinia, Salmonella, Campylobacter, E.coli O157-H7, enteric viruses (person to person too)
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Receptive anal intercourse, oral-anal sex (anilingus) is risky for contraction of?
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Giardia and/or Clostridium histolyticum
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Shiga toxin producing E coli are afebrile versus (see other side of card)
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Salmonella, Campylobacter and Shigella are febrile. All with bloody diarrhea and abd pain
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Rx for noninflammatory diarrhea:
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Bismuth subsalicylates (Pepto-Bismol or Kaopectate) and loperamide (Immodium)
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What does sed rate help reveal?
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Inflammatory activity is suggested with this test running positive (red cell falls a certain distance in a tube, the greater the distance, the greater the inflammatory response of the pnt's immune system is)
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How do they test for lactoferrin, a neutrophil product (eg. for C. difficile colitis diarrhea)?
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Latex agglutination test
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