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13 Cards in this Set

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UTI
E. coli (75-95%) occasionally proteus mirabillis, klebsiella pneumoniea or staphylococcus saprophyticus
TMP-SMX- bactrim (resistance >20%)
Ampicillin (resistance >20%)
Fluoroquinolones (resistance <10%)
Amoxicillin + Clavulinic acid (resistance < 10%)
Pharyngitis causes
Major cause viral- influenza, parainfluenza, coronavirus, rhinovirus, HSV, EBV, HIV

Group A Strep, Mycoplasma pnuemaniae, Chlamydophila pneumoniae, N. gonorrhoeae, groups C and G, etc.

Allergy
Bacterial Sinusitis vs Viral Sinusitis diagnosis
Bacterial lasts greater than 10 days or onset with severe symptoms (fever >102 and purulent nasal discharge ro facial pain) lasting 3 consecutive days at the beginning of illness or onset with worsening symptoms following a viral URI that lasted 5-6 days and was improving
Non purulent Cellulitis causes
Beta hymolytic streptococci and S. aureus are most common

treat with
adults; kids

Dicloxacillin 500 mg every 6 hours; 25-50 mg/kd in four doses

Cephalexin- 500 mg every 6 hours; 25-50 mg/kg in 3-4 doses

Clindamycin-300-450 mg every 6-8 hours; 20-30 mg/kg in 4 doses
Rhus dermatitis topical treatment
Topical

Topical astringents such as aluminum acetate or aluminum sulfate calcium acetate may be used to dry weekping lesions.

High potency topical corticosteroids (avoid on thin skin of face, genitals, or intertriginous areas), clobetasol propionate 0.05% cream
Systemic treatment

Sedating antihistamines do not reduce the pruritis but do help with sleep. Nonsedating antihistamines should not be used

Systemic corticosteroids- oral prednisone taper 2-3 weeks (60-40-20 mg). IM dose of 1 mg/kg triamcinolone acetonide + betamethasone (0.1 mg/kg)

Antibiotics if infection is suspected
Streptococcal tonsillopharyngitis treatment
Penicillin V- 10 days

Amoxicillin is often used for children b/c it tasted better

Penicillin G (IM)- single dose
Otitis media adult
Mild to moderate Amoxicillen 500 mg every 12 hours or 250 mg every 8 hours. 5-7 days

Severe disease (fever, significant hearing loss, severe pain or marked erythema)- Amoxicillen 875 mg every 12 hours or 500 mg every 8 hours. 10 days
Otitis externa

Topical treatment
Topical

Antibiotics- ofloxacin, ciprofloxacin, polymyxin B, neomycin, tobramycin, gentamicin

Glucorticoids to reduce inflammation- hydrocortisone
Oral treatment

In mild to moderate cases no difference in clinical response between a topical and TMP-SMX

Deeper tissue infections- ciprofloxacin (500mg BID 7-10 days) or ofloxacin

Pain- NSAIDs
Streptococcal pharyngitis in a beta lactam sensitive pt
Cephalosporins- cefuroxime, cefpodoxime, cefdinir and ceftriaxone

Macrolides (clarithromxin, azithromycin, erythromycin) for pencillin allergic pts
Acute viral rhinosinusitis
NSAIDs and acetaminophen

Saline (or STERILE water) irrigation

Intranasal glucocorticoids- decrease inflammation (systemic glucocoritcoids are recommended against)

Topical decongestants- oxymetazoline--use sparingly to avoid rebound congestion

Oral decongestants

Mucolytics- guaifenesin
Acute bacterial rhinosinusitis
Amoxicillen-clavulanate 5-7 days (according to UptoDate) 500mg/125mg TID or 875mg/125mg BID

What about penicillin sensitive pts?
Doxycycline or levofloxacin or moxifloxacin
Purulent cellulitis
Suspect MRSA
Treat empirically with clindamycin, TMP-SMX, Tetracycline (doxycycline or minocycline) linezolid or tedizolid
Otitis media adult penicillin allergy
Pts who report an allergy but did not experience urticaria or anaphylaxis

Cefdinir- 300 mg BID or 600 mg 1x/day

Cefpodoxime- 200 mg BID

Cefuroxime- 500 mg BID

Ceftriaxone- 2 g IM or IV 1x
Pts with a severe allergy to beta lactam antibiotic

Macrolide- erythromycin + sulfisoxazole
or
Azithromycin
or
Clarithromycin
TMP-SMX may be used in regions where pneumococcal resistance is not a concern