Family Medicine 74: Diabetes Mellitus

Front 1

adults over ___ should be screened every ___ for DM

Back 1

45
3 years

Front 2

DM is diagnosed if one of ___ (3) is present

Back 2

2 FPG measurements >=126
1 FPG measurement >=200
GTT exceeds 200 within 2 h

Front 3

initial DM2 drug regimen: ___
or ___, if obese

Back 3

glipizide 5mg qd
metformin 500 mg qd

Front 4

HbA1c should be measured every ___
goal is ___

Back 4

6m
<7%

Front 5

DM1 is ___% of DM

Back 5

5-10%

Front 6

glipizide is a ___ drug

Back 6

sulfonylurea

Front 7

T/F: urine glucose levels are important in screening

Back 7

false

Front 8

T/F: urine ketones levels are important in management

Back 8

true

Front 9

___% of DM2 pts are obese

Back 9

80

Front 10

recommended exercise regime:
aerobics ___ per week for ___ minutes

Back 10

3--5
30--45

Front 11

6 oral hypoglycemic families

Back 11

sulfonulurea
a-glucosidase inhibitor
biguanide
non-sulfonylurea secretagogue
thiazolidinedione
DPP-4 inhibitor

Front 12

metformin can cause ___ but this is rare
because of this, it's contraindicated in ___

Back 12

lactic acidosis
renal failure

Front 13

metformin causes less ___ than other hypoglycemic agents

Back 13

weight gain

Front 14

4 common metformin SEs

Back 14

nausea
vomiting
diarrhea
metallic taste in mouth

Front 15

1 a-glucosidase inhibitor

Back 15

acarbose

Front 16

2 TZDs

Back 16

pioglitazone
rosiglitazone

Front 17

___ must be monitored in pts taking TZDs

Back 17

LFTs

Front 18

LFT regime for TZD-taking patients (2)

Back 18

every 2m for first year
periodically thereafter

Front 19

DPP-4 inhibitors work via ___

Back 19

inhibiting deactivation of incretin hormones

Front 20

2 incretins

Back 20

GLP-1
GIP (gastric inhibitory peptide)

Front 21

1 DPP-4 inhibitor

Back 21

sitagliptin

Front 22

2 indications for insulin in DM2

Back 22

in addition to oral hypoglycemics
as initial tx

Front 23

insulin is indicated as initial tx for DM2 patients if ___

Back 23

glucose >400
young, non-obese, symptomatic

Front 24

___ insulin is good at controlling postprandial sugar

Back 24

short-acting

Front 25

long acting insulin is associated with low rates of ___ (2)

Back 25

hypoglycemia
weight gain

Front 26

3 rapid acting insulins

Back 26

lispro
aspart
inhaled

Front 27

rapid acting insulins have onset in ___ hrs,
peak at ___ hrs,
and act for ___ hrs

Back 27

0.2--0.5
0.5--1
3--5

Front 28

1 short-acting insulin

Back 28

regular

Front 29

short acting insulins have onset in ___ hrs,
peak at ___ hrs,
and act for ___ hrs

Back 29

0.5--1
2--3
4--12

Front 30

1 intermediate-acting insulin

Back 30

NPH

Front 31

intermediate acting insulins have onset in ___ hrs,
peak at ___ hrs,
and act for ___ hrs

Back 31

1--2
4--5
10--20

Front 32

2 long-acting insulins

Back 32

glargine
detemir

Front 33

long acting insulins have onset in ___ hrs,
peak at ___ hrs,
and act for ___ hrs

Back 33

1--2
no peak
24

Front 34

normal insulin regimen for DM1 pts:
either ___ or ___

Back 34

split regimen
glargine + preprandial rapid-acting

Front 35

split regimen means injections of ___ at ___ and ___

Back 35

regular/NPH mix
before breakfast
before supper

Front 36

2 non-insulin injectables
only ___ can be used in DM1

Back 36

exenatide
pramlintide
pramlindtide

Front 37

exenatide is a ___
it is indicated for ___

Back 37

incretin mimetic
patients who failed metformin mono- or combination tx

Front 38

pramlintide is a ___
it does ___

Back 38

amylin analog
glucagon inhibition
appetite reduction

Front 39

6 recommended values for DM pts

Back 39

HbA1C<7%
80<FPG<120
BP<130/85
LDL<100
HDL>40
TAG<150

Front 40

3 vaccines mandated for DM pts

Back 40

flu
S. pneumoniae
tetanus

Front 41

DM pts should get S. pneumoniae vaccine every ___
and tetanus every ___

Back 41

5--7 years
10 years