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19 Cards in this Set
- Front
- Back
What types of NTs / receptors are involved in a parasympathetic pathway? |
- Preganglionic (long) releases ACh on Nicotinic receptor
- Postganglionic (short) releases ACh on Muscarinic receptor (eg, cardiac muscle, smooth muscle, gland cells, nerve terminals) |
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What types of NTs / receptors are involved in a sympathetic pathway to sweat glands?
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- Preganglionic (short) releases ACh on Nicotinic receptor (sympathetic chain)
- Postganglionic (long) releases ACh on Muscarinic receptor (same NTs and receptors as parasympathetic) |
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What types of NTs / receptors are involved in a sympathetic pathway to cardiac muscle, smooth muscle, gland cells, and nerve terminals?
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- Preganglionic (short) releases ACh on Nicotinic receptor (sympathetic chain)
- Postganglionic (long) releases NE on α and β receptors |
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What types of NTs / receptors are involved in a sympathetic pathway to renal vasculature and smooth muscle?
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- Preganglionic (short) releases ACh on Nicotinic receptor (sympathetic chain)
- Postganglionic (long) releases Dopamine on D1 receptors |
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What types of NTs / receptors are involved in a pathway to the adrenal medulla?
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- Preganglionic releases ACh on Nicotinic receptor on adrenal medulla
- Adrenal medulla releases Epi and NE |
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What types of NTs / receptors are involved in a somatic pathway to the skeletal muscle?
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Voluntary motor nerve releases ACh on Nicotinic receptor on skeletal muscle
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What nerve terminals does botulinum toxin affect?
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Botulinum toxin prevents release of Ach at all cholinergic terminals |
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What are the types of ACh receptors?
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- Nicotinic ACh receptors
- Muscarinic ACh receptors |
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What are the characteristics of a nicotinic ACh receptors?
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Ligand-gated Na+/K+ channels |
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Which type of receptor is found in autonomic ganglia?
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Nn - Nicotinic ACh receptors, ligand-gated Na+/K+
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Which type of receptor is found in neuromuscular junctions?
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Nm - Nicotinic ACh receptors, ligand-gated Na+/K+
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What are the characteristics of muscarinic ACh receptors?
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G-protein coupled receptors that usually act through 2nd messengers
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What are the types of Muscarinic ACh receptors?
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- M1
- M2 - M3 - M4 - M5 |
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What are the types of G-protein receptors?
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- Sympathetic: α1, α2, β1, β2
- Parasympathetic: M1, M2, M3 - Dopamine: D1, D2 - Histamine: H1, H2 - Vasopressin: V1, V2 |
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What are the sympathetic G-protein receptors? Class?
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What are the parasympathetic G-protein receptors? Class?
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A - B - M - D - H - V |
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What are the dopamine G-protein receptors? Class?
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A - B - M - D - H - V |
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What are the histamine G-protein receptors? Class?
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A - B - M - D - H - V |
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What are the vasopressin G-protein receptors? Class?
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A - B - M - D - H - V |