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19 Cards in this Set

  • Front
  • Back

What types of NTs / receptors are involved in a parasympathetic pathway?

- Preganglionic (long) releases ACh on Nicotinic receptor
- Postganglionic (short) releases ACh on Muscarinic receptor (eg, cardiac muscle, smooth muscle, gland cells, nerve terminals)
- Preganglionic (long) releases ACh on Nicotinic receptor
- Postganglionic (short) releases ACh on Muscarinic receptor (eg, cardiac muscle, smooth muscle, gland cells, nerve terminals)
What types of NTs / receptors are involved in a sympathetic pathway to sweat glands?
- Preganglionic (short) releases ACh on Nicotinic receptor (sympathetic chain)
- Postganglionic (long) releases ACh on Muscarinic receptor 

(same NTs and receptors as parasympathetic)
- Preganglionic (short) releases ACh on Nicotinic receptor (sympathetic chain)
- Postganglionic (long) releases ACh on Muscarinic receptor

(same NTs and receptors as parasympathetic)
What types of NTs / receptors are involved in a sympathetic pathway to cardiac muscle, smooth muscle, gland cells, and nerve terminals?
- Preganglionic (short) releases ACh on Nicotinic receptor (sympathetic chain)
- Postganglionic (long) releases NE on α and β receptors
What types of NTs / receptors are involved in a sympathetic pathway to renal vasculature and smooth muscle?
- Preganglionic (short) releases ACh on Nicotinic receptor (sympathetic chain)
- Postganglionic (long) releases Dopamine on D1 receptors
What types of NTs / receptors are involved in a pathway to the adrenal medulla?
- Preganglionic releases ACh on Nicotinic receptor on adrenal medulla
- Adrenal medulla releases Epi and NE
What types of NTs / receptors are involved in a somatic pathway to the skeletal muscle?
Voluntary motor nerve releases ACh on Nicotinic receptor on skeletal muscle
What nerve terminals does botulinum toxin affect?

Botulinum toxin prevents release of Ach at all cholinergic terminals

What are the types of ACh receptors?
- Nicotinic ACh receptors
- Muscarinic ACh receptors
What are the characteristics of a nicotinic ACh receptors?

Ligand-gated Na+/K+ channels
- Nn - found in autonomic ganglia
- Nm - found in neuromuscular junction subtypes

Which type of receptor is found in autonomic ganglia?
Nn - Nicotinic ACh receptors, ligand-gated Na+/K+
Which type of receptor is found in neuromuscular junctions?
Nm - Nicotinic ACh receptors, ligand-gated Na+/K+
What are the characteristics of muscarinic ACh receptors?
G-protein coupled receptors that usually act through 2nd messengers
What are the types of Muscarinic ACh receptors?
- M1
- M2
- M3
- M4
- M5
What are the types of G-protein receptors?
- Sympathetic: α1, α2, β1, β2
- Parasympathetic: M1, M2, M3
- Dopamine: D1, D2
- Histamine: H1, H2
- Vasopressin: V1, V2
What are the sympathetic G-protein receptors? Class?


- α1: q
- α2: i
- β1: s
- β2: s

What are the parasympathetic G-protein receptors? Class?


- M1: q
- M2: i
- M3: q






A - B - M - D - H - V

What are the dopamine G-protein receptors? Class?


- D1: s
- D2: i



A - B - M - D - H - V

What are the histamine G-protein receptors? Class?


- H1: q
- H2: s



A - B - M - D - H - V

What are the vasopressin G-protein receptors? Class?


- V1: q
- V2: s



A - B - M - D - H - V