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72 Cards in this Set

  • Front
  • Back

What is the dominant normal flora in the skin?

Staphylococcus epidermidis
What is the dominant normal flora in the nose?
- Staphylococcus epidermidis
- Colonized by Staphylococcus aureus
What is the dominant normal flora in the oropharynx?
Viridans group Streptococci
What is the dominant normal flora in dental plaques?
Streptococcus mutans
What is the dominant normal flora in the colon?
Bacteroides fragilis > E. coli
What is the dominant normal flora in the vagina?
- Lactobacillus
- Colonized by E. coli and Group B Strep
What is the normal flora in neonates delivered by C-section?
No flora, but rapidly colonized after birth
Which bugs cause food poisoning that starts quickly and ends quickly?
- Staphylococcus aureus (preformed toxin)
- Bacillus cereus
Which microorganisms cause food poisoning?
- Bacillus cereus
- Clostridium botulinum
- Clostridium perfringens
- E. coli O157:H7
- Salmonella
- S. aureus
- Vibrio parahaemolyticus and Vibrio vulnificus
Which microorganism causes food poisoning after eating reheated rice?
Bacillus cereus ("Food poisoning from reheated rice, Be serious!")
Which microorganism causes food poisoning after eating improperly canned foods (sign is bulging cans)?
Clostridium botulinum
Which microorganism causes food poisoning after eating reheated meat dishes?
Clostridium perfringens
Which microorganism causes food poisoning after eating undercooked meat?
E. coli O157:H7
Which microorganism causes food poisoning after eating poultry, meat, or eggs?
Salmonella
Which microorganism causes food poisoning after eating meats, mayonnaise, or custard?
Staphylococcus aureus (preformed toxin)
Which microorganism causes food poisoning after eating contaminated seafood?
- Vibrio parahaemolyticus
- Vibrio vulnificus
Which microorganism causes wound infections from contact with contaminated water or shellfish?
Vibrio vulnificus
Which bugs cause bloody diarrhea?
- Campylobacter
- Entamoeba histolytica
- Enterohemorrhagic E. coli (EHEC)
- Enteroinvasive E. coli (EIEC)
- Salmonella
- Shigella
- Yersinia enterocolitica
Which bug that causes bloody diarrhea is comma- or S-shaped and grows at 42°C?
Campylobacter
Which bug that causes bloody diarrhea is a protozoan, causes amebic dysentery and liver abscesses?
Entamoeba histolytica
Which bug that causes bloody diarrhea can cause Hemolytic Uremic Syndrome and makes Shiga-like toxin?
Enterohemorrhagic E. coli (EHEC) - O157:H7
Which bug that causes bloody diarrhea invades colonic mucosa?
Enteroinvasive E. coli (EIEC)
Which bug that causes bloody diarrhea is lactose (-), has flagellar motility, animal reservoir, and especially found in poultry and eggs?
Salmonella (remember flagella because salmon swim)
Which bug that causes bloody diarrhea is lactose (-), has a very low ID50, produces Shiga toxin, only human reservoir, and causes bacillary dysentery?
Shigella
Which bug that causes bloody diarrhea is associated with day-care outbreaks and pseudoappendicitis?
Yersinia enterocolitica
Which bugs cause watery diarrhea?
- Clostridium difficile
- Clostridium perfringens
- Enterotoxigenic E. coli (ETEC)
- Giardia and Cryptosporidium in immunocompromised
- Vibrio cholerae
- Rotavirus, Norovirus
Which bug that causes watery diarrhea causes pseudomembranous colitis, caused by antibiotics, and occasionally may be bloody?
Clostridium difficile
Which bug that causes watery diarrhea also causes gas gangrene?
Clostridium perfringens
Which bug that cause watery diarrhea is aka travelers' diarrhea and produces heat-labile (LT) and heat-stable (ST) toxins?
Enterotoxigenic E. coli (ETEC)
Which protozoa can cause watery diarrhea in healthy patients?
Giardia
Which protozoa can cause watery diarrhea in immunocompromised patients?
Cryptosporidium
Which bug that causes watery diarrhea is comma-shaped, associated with "rice-water" diarrhea, and often from infected seafood?
Vibrio cholerae
Which viruses cause watery diarrhea?
- Rotavirus
- Norovirus
What are the common causes of pneumonia in neonates?
- Group B streptococci
- E. coli
What are the common causes of pneumonia in children (4 weeks - 18 years)?
Runts May Cough Chunky Sputum
- Viruses (RSV)
- Mycoplasma
- Chlamydia trachomatis (infants - 3 years)
- Chlamydophila pneumoniae (school-aged children)
- S. pneumoniae
What are the common causes of pneumonia in adults (18-40 years)?
- Mycoplasma
- Chlamydophila pneumoniae
- S. pneumoniae
What are the common causes of pneumonia in adults (40-65 years)?
- S. pneumoniae
- H. influenzae
- Anaerobes
- Viruses
- Mycoplasma
What are the common causes of pneumonia in elderly (>65)?
- S. pneumoniae
- Influenza virus
- Anaerobes
- H. influenzae
- Gram negative rods
Which bugs are common in alcoholics and IV drug users?
- S. pneumoniae
- Klebsiella
- Staphylococcus
Which bugs are common to aspirate?
Anaerobes
Which bugs are "atypical"?
- Mycoplasma
- Legionella
- chlamydia
Which bugs are associated with Cystic Fibrosis?
- Pseudomonas
- S. aureus
- S. pneumoniae
Which bugs are common in the immunocompromised?
- Staphylococcus
- Enteric G- rods
- Fungi
- Viruses
- P. jirovecii (with HIV)
What are the nosocomial (hospital acquired) infections?
- Staphylococcus
- Pseudomonas
- Other enteric G- rods
Which bacteria are common post-viral infection?
- Staphylococcus
- H. influenzae
- S. pneumoniae
What are the common causes of meningitis in newborns (0-6 months)?
* Group B streptococci
* E. coli
- Listeria

* = same as pneumonia
What are the common causes of meningitis in children (6 months - 6 years)?
* S. pneumoniae
- N. meningitidis
- H. influenzae type B
- Enteroviruses

* = same as pneumonia
What are the common causes of meningitis in 6 to 60 year olds?

* S. pneumoniae
- N. meningitidis
- Enteroviruses
- HSV

* = same as pneumonia

What is the number one cause of meningitis in teens?
N. meningitidis
What are the common causes of meningitis in elderly (>60)?
* S. pneumoniae
* G- rods
- Listeria

* = same as pneumonia
How should you treat suspected cases of meningitis?
Treat empirically with Ceftriaxone and Vancomycin
- Add Ampicillin if Listeria is suspected
What are the viral causes of meningitis?
- Enteroviruses (especially coxsackievirus)
- HSV-2 (HSV-1 = encephalitis)
- HIV
- West Nile Virus
- VZV
What are the common causes of meningitis in HIV patients?
- Cryptococcus
- CMV
- Toxoplasmosis (brain abscesses)
- JC virus (PML)
What are cases of meningitis due to H. influenzae more common?
In unimmunized children (rates have gone down significantly in last 10-15 years since introduction of the conjugate H. influenzae vaccine)
What are the CSF findings in bacterial meningitis?
- ↑ opening pressure
- ↑ PMNs
- ↑ Protein
- ↓ Glucose
What are the CSF findings in fungal / TB meningitis?
- ↑ opening pressure
- ↑ lymphocytes
- ↑ Protein
- ↓ Glucose
What are the CSF findings in viral meningitis?
- Nl/↑ opening pressure
- ↑ lymphocytes
- Nl/↑ Protein
- Nl Glucose
What kind of infection is likely if there are increased PMNs in the CSF?
Bacterial meningitis
What kind of infection is likely if there are increased lymphocytes in the CSF?
Either fungal / TB meningitis or viral meningitis
What kind of infection is likely if there is a normal glucose?
Viral meningitis
(both bacterial and fungal/TB cause decreased glucose)
What is the most common cause of Osteomyelitis?
Staphylococcus aureus
What should you suspect as the cause of osteomyelitis in a patient who is sexually active?
- Neisseria gonorrhoeae (rare)
- Septic arthritis more common
What should you suspect as the cause of osteomyelitis in a patient who is diabetic?
- Pseudomonas aeruginosa
- Serratia

(Same as IV drug users)
What should you suspect as the cause of osteomyelitis in a patient who is an IV drug user?

- Pseudomonas aeruginosa
- Serratia

(Same as for diabetics)

What should you suspect as the cause of osteomyelitis in a patient who has sickle cell disease?
Salmonella
What should you suspect as the cause of osteomyelitis in a patient who has a prosthetic joint replacement?

- S. aureus
- Staphylococcus epidermidis

What should you suspect as the cause of osteomyelitis in a patient who has vertebral involvement?
Mycobacterium tuberculosis (Pott disease)
What should you suspect as the cause of osteomyelitis in a patient who has cat and dog bites?
Pasteurella multocida
What should you suspect as the cause of osteomyelitis in a patient who has no other information available?
Staphylococcus aureus (most common overall)
When do most cases of Osteomyelitis occur?
Most in children
What are the lab tests in a patient with Osteomyelitis?
Elevated CRP and ESR (but non-specific)
What does osteomyelitis look like on radiographs? MRI?
- Radiograph: more subtle (arrow in top picture)
- MRI: more easily seen
- Radiograph: more subtle (arrow in top picture)
- MRI: more easily seen