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82 Cards in this Set

  • Front
  • Back
special culture requirements

H. influenzae
chocolate agar with factors V (NaD+) and X (hematin)
special culture requirements

N. gonorrhoeae
Thayer-martin or VPN media

Vancomycin (inhibit G (+))
Polymyxin (inhibit G (-))
Nystatin (inhibit fungi)
special culture requirements

B. pertussis
Bordet-Gengou (potato) agar
special culture requirements

C. diphtheriae
tellurite plate, Loffler's media
special culture requirements

M. tuberculosis
Lowenstein-Jensen Agar
special culture requirements

M. pneumoniae
Eaton's agar
special culture requirements

lactose-fermenting enterics
pink colonies on macConkey's agar (fermentation produces acid, turning plate pin)

E. coli is also grown on EMB (eosin-methylene blue) agar as blue-black colonies with metallic sheen
special culture requirements

legionella
charcoal yeast extract agar buffered with cysteine
special culture requirements

fungi
sabouraud's agar
obligate anerobes
anaerobes Can't Breath Air

Clostridium
Bacteroides
Actinomyces

lack catalase and or superoxide dismutase
Obligate Intracellular bugs
Rickettsia
chlamydia

can't make own atp
facultative intracellular
Some Nasty Bugs May Live FactultativeLy

Salmonella
Neisseria
Brucella
Mycobacterium
Listeria
Francisella
Legionella
Encapsulated bacteria
Kapsules Shield SHiN

Klebsiella pneumoniae
Salmonella
Streptococcus pneumoniae
Haemophilus influenza type B
Neisseria meningitidis

positive quellung reaction

SHiN can make IgA protease causing meningitis, and take up DNA from environment (transformation)

Capsules serve as antigens in vaccines
Urease positive bugs
Particular Kinds Have Urease

Proteus
Klebsiella
H. pylori
Ureaplasma
Pigment producing bacteria
actinomyces israelii - yellow sulfur granules
s. aureus - yellow pigment
pseudomonas aeruginosa - blue green
serratia marcescens - red
bugs with toxins

corynebacterium diphtheriae
AB toxin

ianctivate elongation factor 2 (EF2)

cause pharyngitis and pseudomembrane in throat
bugs with toxin

vibrio cholerae
ADP ribosylate G protein to stimulate AC.
increases pumping of Cl into gut and decreased Na absorption.
h2o into gut, rice water diarrhea
bugs with toxin

e. coli (ETEC)
heat labile toxin stimulate AC
heat stable toxin stimulate GC

both cause watery diarrhea.
bugs with toxin

bordetella pertussis
increases cAMP by inhibiting Gi
causes whooping cough
inhibits chemokine receptor, causing lymphocytosis.
bugs with toxin

clostridium perfringens
a toxin causes gas gangrene
double zone of hemolysis on blood agar.
bugs with toxin

c. tetani
blocks relase of GABA and glycine.
causes lockjaw.
bugs with toxin

c. botulinum
block Ach release; anticholinergic symptoms, CNs paralysis, esp. CN.

spores found in canned food (at home) and honey (floppy baby)
bugs with toxin

bacillus anthracis
edema factor, part of toxin complex is AC.
bugs with toxin

shigella
shiga toxin (also made by e. coli o157:h7) cleaves host rRNA (60S ribosome)

enhances cytokine release causing HUS
bugs with toxin

s. pyogenes
streptolysin O is hemolysin
Ag for ASO ab.
parasite hints

brain cysts, seizures
taenia solium (cysticercosis)
parasite hints

liver cysts
echinococcus granulosus
parasite hints

b12 deficiencyy
diphyllobothrium latum
parasite hints

biliary tract disease, cholangiosarcoma
clonorchis sinensis
parasite hints

hemoptysis
paragoniums westermani
parasite hints

portal hypertension
schistosoma manson
parasite hints

hematuria, bladder cancer
schistosoma haematobium
parasite hints

microcytic anemia
ancylostoma
necator
parasite hints

perianal pruritus
enterobius
typhoid fever
caused by salmonella typhi
typhus
rickettsia prowazekii (epidemic)
rickettsia typhi (endemic)
rickettsia tsutsugamushi (scrub typhus)
chlamydia trachomatis
bacteria, STD
treponema
spirochete
causes syphilis (t. pallidum) or yaws (t. pertenue)
trichomonas vaginalis
protozoan, STD
trypanosoma
protozoan, causes chagas' disease (t. cruzi) or african sleeping sickness
toxoplama
protozoan, a TORCH infection
trichinella spiralis
nematode in undercooked meat
taenia solium
tapeworm larvae (intestinal infection) or eggs (neurocysticercosis) in pork
viral vaccines

killed
rabies
influenza
salk poli
HAV
viral vaccines

recombinant
HBV (recombinant HBsAg)
HPV (6, 11, 16, 18)
rubella
togavirus
german 3 day measles
rubeola
parmyxovirus
measles
roseola
herpesvirus (HHV-6)
high fever followed by diffuse maculopapular rash
varicella
herpesvirus; chickenpox and zoster
variola
poxvirus; small pox
bug hits (if all else fails)

pus, empyema, abscess
s. aureus
bug hits (if all else fails)

pediatric infection
h. influenza (including epiglottitis)
bug hits (if all else fails)

pneumonia in cystic fibrosis, burn infection
pseudomonas aeruginosa
bug hits (if all else fails)

branching rods in oral infection, sulfur granules
actinomyces israelii
bug hits (if all else fails)

traumatic open wound
clostridium perfringens
bug hits (if all else fails)

surgical wound
s. auerus
bug hits (if all else fails)

dog or cat bite
pasteurella multocida
bug hits (if all else fails)

currant jelly sputum
klebsiella
bug hits (if all else fails)

positive PAS stain
tropheryma whippelii (whipple's disease)
bug hits (if all else fails)

sepsis/meningitis in newborn
group b strep
bug hits (if all else fails)

health care provider
HBV from needle stick
bug hits (if all else fails)

fungal infection in diabetic
mucor or rhizopus spp.
bug hits (if all else fails)

asplenic patient
encapsulated microbes, especially SHiN

s. pneumoniae
H. influenzae type b
n. meningitidis
bug hits (if all else fails)

chronic granulomatous disease
catalase postiive mcirobes

s. aureus
nocardia spp.
serratia marcescens
pseudomonas cepacia
aspergillus spp
bug hits (if all else fails)

neutropenic patients
candidia albicans (systemic)
bug hits (if all else fails)

bilateral bell's palsy
borrelia burgdorferi (lyme disease)
nematode (roundworm)

enterobius vermicularis (pinworm)
food contaminated with eggs; intestinal infection; causes anal pruritis (the scotch tape test)

tx: -bendazoles or pyrantel pamoate
nematode (roundworm)

ascaris lumbricoides (giant roundworm)
eggs are visible in feces; intestinal infection

tx: -bendazoles or pyrantel pamoate
nematode (roundworm)

trichinella spiralis
undercooked meat, usually pork; inflammation of muscle (larvae encyst in muscle), periorbital edema

tx: -bendazoles
nematode (roundworm)

strongyloides stercoralis
larvae in soil penetrate the skin; intestinal infection; causes vomiting, diarrhea and anemia

tx: -bendazoles or ivermectin
nematode (roundworm)

ancylostoma duodenale, necator americanus (hookworms)
larvae penetrate skin of feet; insteinal infection can cause anemia (sucks blood from intestinal walls)

tx: -bendazoles or pyrantel pamoate (worms are BENDy; treat with meBENDazole)
nematode (roundworm)

dracunulus medinensis
in drinking water; skin inflammation and ulceration

tx: niridazole
nematode (roundworm)

onchocerca volvulus
transmitted by female blackflies; causes hyperpigmented skin and river blindness (remember blackflies, black skin nodules, "black sight"). can have allergic reaction to microfilaria

tx: ivermectin (ivermectin for rIVER blindness)
nematode (roundworm)

loa loa
transmitted by deer fly, horse fly, and mango fly; causes swelling in skin (can see worm crawling in conjunctiva)

tx: diethylcarbamazine
nematode (roundworm)

wuchereria bancrofti
female mosquito; causes blockage of lymphatic vessels (elephantiasis). take 9 months to 1 year after bite to get elephantiasis symptoms

tx: diethylcarbamazine
nematode (roundworm)

toxocara canis
food contamined with eggs; causes granulomas (if in retina --> blindness) and visceral larva migrans

tx: diethylcarbamazine
cestodes (tapeworms)

taenia solium
ingestion of larvae encysted in undercooked pork leads to intestinal tapeworms. ingestion of eggs causes cysticercosis and neurocysticercosis, mass lesions in brain ("swiss cheese" appearance)

tx: praziquantel (use -bendazoles for neurocysticercosis)
cestodes (tapeworms)

diphyllobothrium latum
ingestion of larve in raw freshwater fish. causese vitamin b12 deficiency, resulting in anemia

tx: praziquantel
cestodes (tapeworms)

echinococcus granulosus
eggs in dog feces when ingested can cause cysts in liver; causes anaphylaxis if echinococcal antigens are released from cysts (surgeons inject ethanol before removal to neutralize antigens).

tx: -bendazoles
trematodes (flukes)

schistosoma
snails are hosts; cercariae penetrate skin of humans; causes granulomas, fibrosis and inflammation of the spleen and liver. chronic infection with s. haematobium can lead to squamous cell carcinoma of the bladder

tx: praziquantel
trematodes (flukes)

clonorchis sinensis
undercooked fish; causes inflammation of the biliary tract --> pigmented gallstones. also associated with cholangiocarcinoma

tx: praziquantel
trematodes (flukes)

paragonimus westermani
undercooked crab meat; causes inflammation and secondary bacterial infection of the lung, causing hemoptysis

tx: praziquantel