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85 Cards in this Set
- Front
- Back
When does implantation occur
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within week 1
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When does the bilaminar disk form?
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within week 2
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When do the primitive streak, notochord and neural plate begin to form?
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within week 3
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when do the neural tube form and organogenesis occur?
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between weeks 3 and 8
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During what time period is the fetus most susceptible to teratogens?
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embryologic period; between weeks 3 and 8
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When do the limb buds begin to form?
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week 4
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When does the heart begin to beat?
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week 4
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when does the fetus look like a baby and begin to move?
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week 8
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when is the earliest one can tell the sex of the baby?
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genitalia have male/female characteristics by week 10
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the alar plate forms what part of the peripheral nervous system?
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sensory
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the basal plate forms what part of the peripheral nervous system?
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motor
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rule of 2's for 2nd week?
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2 germ layers: epiblast, hypoblast
2 cavities: amniotic cavity, yolk sac 2 components to placenta: cytotrophoblasat, syncytiotrophoblast |
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rule of 3's for 3rd week?
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3 germ layers (gastrula): ectoderm, mesoderm, endoderm
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rule of 4's for 4th week?
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4 heart chambers, 4 limb buds
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from whence is the intraembryonic mesoderm and endoderm derived?
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primitive streak (from the epiblast)
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what structures come from the surface ectoderm?
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adenohypophysis; lens of eye; epithelial linings of skin, ear, eye, nose; epidermis
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what structures come from the neuroectoderm?
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neurohypophysis, CNS neurons, oligodendrocytes, astrocytes, ependymal cells, pineal gland
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Which structures come from the neural crest?
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ANS, dorsal root ganglia, melanocytes, chromaffin cells of adrenal mudulla, enterochromaffin cells, pia and arachnoid, celiac ganglion Schwann cells, odontoblasts, parafollicular cells of thyroid, laryngeal cartilage, bones of skull
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what structures arise from the endoderm?
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gut tube epithelium and derivatives (lungs, liver, pancreas, thymus, parathyroid, thyroid follicular cells)
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what structures come from the mesoderm?
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dura mater, connective tissue, muscle, bone, cardiovascular structures, lymphatics, blood, urogenital structures, serous linings of body cavities, spleen, adrenal cortex, kidneys
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neural plate formation is induced by what?
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notochord
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the notochord forms what postnatal structure?
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nucleus pulposus
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fetal alcohol exposure causes what?
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retardation, microcephaly, facial abnormalities, limb dislocation ,heart and lung fistulas
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fetal exposure to ACE inhibitors results in what?
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renal damage
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fetal exposure to cocaine results in what?
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abnormal fetal development and addiction
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fetal DES exposure causes what?
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vaginal clear cell carcinoma
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fetal iodide exposure causes what?
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congenital goiter or hypothyroidism
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fetal thalidomide exposure causes what?
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limb defects (flipper arms) lack of limb bud development
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what is the function of the urachus?
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to remove nitrogenous waste from the fetal bladder
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from what structure are the umbilical arteries and veins derived?
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allantois
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truncus arteriosus gives rise to what?
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ascending aorta and pulmonary trunk
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the bulbus cordis gives rise to what structures?
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smooth parts of left and right ventricle
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the primitive ventricle is analogous to what structure in the adult heart?
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trabeculated parts of left and right ventricle
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the primitive atria give rise to what structures?
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trabeculated left and right atrium
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the left horn of the sinus venosus gives rise to what structure?
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coronary sinus
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the right horn of the sinus venosus gives rise to what structure?
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smooth part of right atrium
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right common cardinal vein and right anterior cardinal vein give rise to what structure in the adult?
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SVC
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when does the bone marrow begin erythropoiesis?
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week 28
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when is the yolk sac most responsible for erythropoiesis?
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weeks 3-8
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what structure(s) is/are responsible for erythropoiesis during weeks 8-28?
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Liver (wk 6-30) and Spleen (wk 9-28)
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the ligamentum teres hepatis is a remnant of what embryologic structure?
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umbilical vein
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in what adult structure is the ligamentum teres hepatis contained?
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falciform ligament
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the medial umbilical ligaments are derived from what embryonic structure?
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umbilical arteries
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the ligamentum arteriosum is derived from what embryonic structure?
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ductus arteriosus
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the ligamentum venosum is derived from what embryonic structure?
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ductus venosus
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the median umbilical ligament is derived from what embryonic structure?
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allantois/urachus
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the nucleus pulposus of intervertebral disks are derived from what embryonic structure?
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notochord
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1st aortic arch gives rise to what structure?
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maxillary artery
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3rd aortic arch gives rise to what structures?
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common carotid artery and proximal part of internal carotid artery
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2nd aortic arch gives rise to what structure?
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stapedial artery and hyoid artery
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4th aortic arch gives rise to what structures?
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left: aortic arch
right: proximal part of right subclavian artery |
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6th aortic arch gives rise to what structure?
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proximal part of pulmonary arteries and ductus arteriosus
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Derivatives of branchial arch 1?
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Meckel's cartilage: Mandible, Malleus, incus, sphenoMandibular ligament
Muscles: Muscles of Mastication, Mylohyoid, anterior belly of digastric, tensor tympani, tensor veli palatini, anterior 2/3 of tongue Nerves: CN V2 and V3 |
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branchial arch 2 derivatives?
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Reichert's cartilage: Stapes, Styloid process, lesser horn of hyoid, Stylohyoid ligament
Muscles: facial expression, Stapedius, Stylohyoid, posterior belly of digastric Nerves: CN VII |
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what is derived from branchial arch 3?
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greater horn of hyoid, stylopharyngeus muscle glossopharyngeal nerve
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branchial arches 4-6 derive what structures?
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thyroid, cricoid, arytenoid, corniculate, cuneiform cartilages; pharyngeal constrictor muscles, cricothyroid, levator veli palatini (4th), intrinsic muscles of larynx (6th, except cricothyroid); CNX; posterior 1/3 of tongue
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which cranial nerves have both sensory and motor components?
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V2, V3, VII, IX, X
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What is the embryologic origin of the external auditory meatus?
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1st branchial cleft
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What structures are derived from the 1st pharyngeal pouch?
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middle ear cavity, eustachan tube, mastoid air cells
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what structures are derived from the 2nd pharyngeal pouch?
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epithelial lining of palatine tonsil
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what structures are derived from the 3rd pharyngeal pouch?
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inferior parathyroids from dorsal wings; thymus from ventral wings
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what structures are derived from the 4th pharyngeal pouch?
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superior parathyroids
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The diaphragm is derived from what embryologic structures?
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Septum transversum, Pleuroperitoneal folds, Body wall, Dorsal mesentery of esophagus
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what structures form the foregut?
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pharynx to duodenum
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what structures form the midgut?
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duodenum to transverse colon
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what structures are in the hindgut?
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distal transverse colon to rectum
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what is gastroschisis?
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failure of lateral body folds to fuse --> extrusion of abdominal contents through abdominal folds --> not covered by membrane
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what is an omphalocele?
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persistence of herniation of abdominal contents into umbilical cord --> contents covered by membrane
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from what tissue is the spleen derived?
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dorsal mesentery
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What hormone stimulates gonadal differentiation to the testes?
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TDF
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What hormone causes regression of the paramesonephric ducts in males?
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mullerian inhibiting factor
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what hormone stimulates the growth of the mesonephric ducts in males?
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testsosterone
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what hormone stimulates regression of mesonephric ducts in females?
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lack of testosterone
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the mesonephric ducts form what structures in the normal male?
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ductus deferens, epididymis, efferent ductules
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what hormone stimulates growth of the paramesonephric ducts in females?
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lack of MIF
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paramesonephric ducts form what structures in the normal female?
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fallopian tube, uterus, upper 1/3 of vagina
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what embryologic structures form the scrotum and labia majora?
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genital swellings
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what embryologic structures form the labia minora?
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urethral folds
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what hormone causes secondary sexual maturation in males?
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Dihydrotestosterone (DHT)
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what embryologic structure forms the clitoris in females?
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genital tubercle
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deficiency in 5-alpha-reductase causes what?
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lack of DHT in males, so there is no secondary sexual differentiation. Testes and internal genitalia are established, but external genitalia are ambiguous
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metanephric duct develops into what structures?
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ureter, renal pelvic and collecting system
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urogenital sinus develops into what structures?
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bladder; prostate and bulbourethral glands in males; lower 2/3 of vagina and hymen in females
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initially what are the layers of the chorionic villi?
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syncitium, cytotrophoblast, connective tissue, endothelium
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what are the layers of the mature chorionic villi?
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syncytium, endothelium
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