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85 Cards in this Set

  • Front
  • Back
When does implantation occur
within week 1
When does the bilaminar disk form?
within week 2
When do the primitive streak, notochord and neural plate begin to form?
within week 3
when do the neural tube form and organogenesis occur?
between weeks 3 and 8
During what time period is the fetus most susceptible to teratogens?
embryologic period; between weeks 3 and 8
When do the limb buds begin to form?
week 4
When does the heart begin to beat?
week 4
when does the fetus look like a baby and begin to move?
week 8
when is the earliest one can tell the sex of the baby?
genitalia have male/female characteristics by week 10
the alar plate forms what part of the peripheral nervous system?
sensory
the basal plate forms what part of the peripheral nervous system?
motor
rule of 2's for 2nd week?
2 germ layers: epiblast, hypoblast
2 cavities: amniotic cavity, yolk sac
2 components to placenta: cytotrophoblasat, syncytiotrophoblast
rule of 3's for 3rd week?
3 germ layers (gastrula): ectoderm, mesoderm, endoderm
rule of 4's for 4th week?
4 heart chambers, 4 limb buds
from whence is the intraembryonic mesoderm and endoderm derived?
primitive streak (from the epiblast)
what structures come from the surface ectoderm?
adenohypophysis; lens of eye; epithelial linings of skin, ear, eye, nose; epidermis
what structures come from the neuroectoderm?
neurohypophysis, CNS neurons, oligodendrocytes, astrocytes, ependymal cells, pineal gland
Which structures come from the neural crest?
ANS, dorsal root ganglia, melanocytes, chromaffin cells of adrenal mudulla, enterochromaffin cells, pia and arachnoid, celiac ganglion Schwann cells, odontoblasts, parafollicular cells of thyroid, laryngeal cartilage, bones of skull
what structures arise from the endoderm?
gut tube epithelium and derivatives (lungs, liver, pancreas, thymus, parathyroid, thyroid follicular cells)
what structures come from the mesoderm?
dura mater, connective tissue, muscle, bone, cardiovascular structures, lymphatics, blood, urogenital structures, serous linings of body cavities, spleen, adrenal cortex, kidneys
neural plate formation is induced by what?
notochord
the notochord forms what postnatal structure?
nucleus pulposus
fetal alcohol exposure causes what?
retardation, microcephaly, facial abnormalities, limb dislocation ,heart and lung fistulas
fetal exposure to ACE inhibitors results in what?
renal damage
fetal exposure to cocaine results in what?
abnormal fetal development and addiction
fetal DES exposure causes what?
vaginal clear cell carcinoma
fetal iodide exposure causes what?
congenital goiter or hypothyroidism
fetal thalidomide exposure causes what?
limb defects (flipper arms) lack of limb bud development
what is the function of the urachus?
to remove nitrogenous waste from the fetal bladder
from what structure are the umbilical arteries and veins derived?
allantois
truncus arteriosus gives rise to what?
ascending aorta and pulmonary trunk
the bulbus cordis gives rise to what structures?
smooth parts of left and right ventricle
the primitive ventricle is analogous to what structure in the adult heart?
trabeculated parts of left and right ventricle
the primitive atria give rise to what structures?
trabeculated left and right atrium
the left horn of the sinus venosus gives rise to what structure?
coronary sinus
the right horn of the sinus venosus gives rise to what structure?
smooth part of right atrium
right common cardinal vein and right anterior cardinal vein give rise to what structure in the adult?
SVC
when does the bone marrow begin erythropoiesis?
week 28
when is the yolk sac most responsible for erythropoiesis?
weeks 3-8
what structure(s) is/are responsible for erythropoiesis during weeks 8-28?
Liver (wk 6-30) and Spleen (wk 9-28)
the ligamentum teres hepatis is a remnant of what embryologic structure?
umbilical vein
in what adult structure is the ligamentum teres hepatis contained?
falciform ligament
the medial umbilical ligaments are derived from what embryonic structure?
umbilical arteries
the ligamentum arteriosum is derived from what embryonic structure?
ductus arteriosus
the ligamentum venosum is derived from what embryonic structure?
ductus venosus
the median umbilical ligament is derived from what embryonic structure?
allantois/urachus
the nucleus pulposus of intervertebral disks are derived from what embryonic structure?
notochord
1st aortic arch gives rise to what structure?
maxillary artery
3rd aortic arch gives rise to what structures?
common carotid artery and proximal part of internal carotid artery
2nd aortic arch gives rise to what structure?
stapedial artery and hyoid artery
4th aortic arch gives rise to what structures?
left: aortic arch
right: proximal part of right subclavian artery
6th aortic arch gives rise to what structure?
proximal part of pulmonary arteries and ductus arteriosus
Derivatives of branchial arch 1?
Meckel's cartilage: Mandible, Malleus, incus, sphenoMandibular ligament
Muscles: Muscles of Mastication, Mylohyoid, anterior belly of digastric, tensor tympani, tensor veli palatini, anterior 2/3 of tongue
Nerves: CN V2 and V3
branchial arch 2 derivatives?
Reichert's cartilage: Stapes, Styloid process, lesser horn of hyoid, Stylohyoid ligament
Muscles: facial expression, Stapedius, Stylohyoid, posterior belly of digastric
Nerves: CN VII
what is derived from branchial arch 3?
greater horn of hyoid, stylopharyngeus muscle glossopharyngeal nerve
branchial arches 4-6 derive what structures?
thyroid, cricoid, arytenoid, corniculate, cuneiform cartilages; pharyngeal constrictor muscles, cricothyroid, levator veli palatini (4th), intrinsic muscles of larynx (6th, except cricothyroid); CNX; posterior 1/3 of tongue
which cranial nerves have both sensory and motor components?
V2, V3, VII, IX, X
What is the embryologic origin of the external auditory meatus?
1st branchial cleft
What structures are derived from the 1st pharyngeal pouch?
middle ear cavity, eustachan tube, mastoid air cells
what structures are derived from the 2nd pharyngeal pouch?
epithelial lining of palatine tonsil
what structures are derived from the 3rd pharyngeal pouch?
inferior parathyroids from dorsal wings; thymus from ventral wings
what structures are derived from the 4th pharyngeal pouch?
superior parathyroids
The diaphragm is derived from what embryologic structures?
Septum transversum, Pleuroperitoneal folds, Body wall, Dorsal mesentery of esophagus
what structures form the foregut?
pharynx to duodenum
what structures form the midgut?
duodenum to transverse colon
what structures are in the hindgut?
distal transverse colon to rectum
what is gastroschisis?
failure of lateral body folds to fuse --> extrusion of abdominal contents through abdominal folds --> not covered by membrane
what is an omphalocele?
persistence of herniation of abdominal contents into umbilical cord --> contents covered by membrane
from what tissue is the spleen derived?
dorsal mesentery
What hormone stimulates gonadal differentiation to the testes?
TDF
What hormone causes regression of the paramesonephric ducts in males?
mullerian inhibiting factor
what hormone stimulates the growth of the mesonephric ducts in males?
testsosterone
what hormone stimulates regression of mesonephric ducts in females?
lack of testosterone
the mesonephric ducts form what structures in the normal male?
ductus deferens, epididymis, efferent ductules
what hormone stimulates growth of the paramesonephric ducts in females?
lack of MIF
paramesonephric ducts form what structures in the normal female?
fallopian tube, uterus, upper 1/3 of vagina
what embryologic structures form the scrotum and labia majora?
genital swellings
what embryologic structures form the labia minora?
urethral folds
what hormone causes secondary sexual maturation in males?
Dihydrotestosterone (DHT)
what embryologic structure forms the clitoris in females?
genital tubercle
deficiency in 5-alpha-reductase causes what?
lack of DHT in males, so there is no secondary sexual differentiation. Testes and internal genitalia are established, but external genitalia are ambiguous
metanephric duct develops into what structures?
ureter, renal pelvic and collecting system
urogenital sinus develops into what structures?
bladder; prostate and bulbourethral glands in males; lower 2/3 of vagina and hymen in females
initially what are the layers of the chorionic villi?
syncitium, cytotrophoblast, connective tissue, endothelium
what are the layers of the mature chorionic villi?
syncytium, endothelium