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26 Cards in this Set

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Question
Answer
What is Type I Familial Dyslipidemia?
hyperchylomicronemia
What is Type IIa Familial Dyslipidemia?
hypercholesterolemia
What is Type IIb Familial Dyslipidemia?
combined hyperlipidemia
What is Type III Familial Dyslipidemia?
dysbetalipoproteinemia
What is Type IV Familial Dyslipidemia?
hypertriglyceridemia
What is Type V Familial Dyslipidemia?
mixed hypertriglyceridemia
What is the INHERITANCE of Type IIa Familial dyslipidemia? (hypercholesterolemia)
autosomal dominant
What is INCREASED in Type I Familial Dyslipidemia?
chylomicrons
What is INCREASED in Type IIa Familial Dyslipidemia (hypercholesterolemia)?
LDL
What is INCREASED in Type Iib Familial Dyslipidemia (combined hyperlipidemia)?
LDL, VDL
What is INCREASED in Type III Familial Dyslipidemia (dysbetalipoproteinemia)?
IDL, VLDL
What is INCREASED in Type IV Familial Dyslipidemia (hypertriglyceridemia)?
VLDL
What is INCREASED in Type V Familial Dyslipidemia (mixed hypertriglyceridemia)?
VLDL, chylomicrons
Type I hyperchylomicronemia ELEVATED BLOOD LEVELS?
TG, cholesterol
Type IIa hypercholesterolemia ELEVATED BLOOD LEVELS?
cholesterol
Type IIb combined hyperlipidemia ELEVATED BLOOD LEVELS?
TG, cholesterol
Type III dysbetalipoproteinemia ELEVATED BLOOD LEVELS?
TG, cholesterol
Type IV hypertriglyceridemia ELEVATED BLOOD LEVELS?
TG
Type V mixed hypertriglyceridemia ELEVATED BLOOD LEVELS?
TG, cholesterol
Type I hyperchylomicronemia PATHOPHYSIOLOGY?
Lipoprotein lipase deficiency, or altered apolipoprotein C-II (co-factor for lipoprotein lipase)
Type IIa hypercholesterolemia PATHOPHYSIOLOGY?
DECREASE LDL receptors
Type IIb combined hyperlipidemia PATHOPHYSIOLOGY?
hepatic OVERPRODUCTION of VLDL
Type III dysbetalipoproteinemia PATHOPHYSIOLOGY?
ALTERED apolipoprotein E
Type IV hypertriglyceridemia PATHOPHYSIOLOGY?
hepatic OVERPRODUCTION of VLDL
Type V mixed hypertriglyceridemia PATHOPHYSIOLOGY?
INCREASE production/DECREASE clearance of VLDL and chylomicrons