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114 Cards in this Set

  • Front
  • Back
Abdominal pain, ascites, hepatomegaly
Budd-Chiari Syndrome (posthepatic venous thrombosis)
Achilles tendon xanthoma
Familial hypercholesterolemia
Adrenal hemorrhage, hypotension, DIC
Waterhouse-Friderichsen syndrome (meningococcemia)
Arachnodactyly, lens dislocation, aortic dissection, hyperflexible joints
Marfan's syndrome (fibrillin defect)
Athlete with polycythemia
Erythropoietin injection
Back pain, fever, night sweats, weight loss
Pott's disease (vertebral tuberculosis)
Bilateral hilar adenopathy, uveitis

hilum - wnęka,
uveitis - zapalenie błony naczyniowej oka;
Sarcoidosis (noncaseating granulomas)
Blue sclera

sclera - twardówka
Osteogenisis imperfecta (collagen defect)
Bluish line on gingiva
Burton's line (lead poisoning)
Bone pain, bone enlargement, arthritis
Paget's disease of bone (Increased osteoblastic and osteoclastic activity)
Bounding pulses, diastolic heart murmur, head bobbing
Aortic regurgitation
Café-au-lait spots, Lisch nodules (iris hamartoma)
Neurofibromatosis type I
(+ pheochromocytoma, optic gliomas)

Neurofibromatosis type II
(+ bilateral acoustic neuromas)
Café-au-lait spots, polyostotic fibrous dysplasia, precocious puberty
McCune-Albright syndrome (mosaic G-protein signaling mutation)
Calf pseudohypertrophy
Muscular dystrophy (most commonly Duchenne's)
"Cherry red spot" on macula
Tay-Sachs (ganglioside accumulation) or Niemann-Pick (sphingomyelin accumulation), central retinal artery occlusion
Chest pain, pericardial effusion/friction rub, persisten fever following MI
Dressler's syndrome (autoimmune-mediated post-MI fibrinous pericarditis, 1-12 weeks after acute episode)
Child uses arms to stand up from squat
Gowers' sign (Duchenne muscular dystrophy: X linked recessive deleted dystrophin gene)
Child with fever develops red rash on face that spreads to body
"Slapped cheeks" (erythema infectiosum/fifth disease: parvovirus B19)
Chorea, dementia, caudate degeneration
Huntington's disease (autosomal dominant CAG repeat expansion)
Chronic exercise intolerance with myalgia, fatigue, painful cramps
McArdle's disease (muscle phosphorylase deficiency)
Cold intolerance
Hypothyroidism
Conjugate lateral gaze palsy horizontal diplopia
Internuclear ophtalmoplegia (damage to MLF; bilateral [multiple sclerosis], unilateral [stroke])
Continuous "machinery" heart murmur
PDA (close with indomethacin; open with misoprostol)
Cutaneous/dermal edema due to connective tissue deposition
Myxedema (hypothyroidism, Graves' disease)
Dark purple skin/mouth nodules
Kaposi's sarcoma (usually AIDS patients [gay men]: associated with HHV-8)
Deep, labored breathing/hyperventilation
Kussmaul breathing (diabetic ketoacidosis)
Dermatitis, dementia, diarrhea
Pellagra (niacin [vitamin B3] deficiency)
Dilated cardiomyopathy, edema, polyneuropathy
Wet beriberi (thiamine [vitamin B1] deficiency)
Dog or cat bite resulting in infection
Pasteurella multocida (cellulitis at inoculation site)
Dry eyes, dry mouth, arthritis
Sjögren's syndrome (autoimmune destruction of exocrine glands)
Dysphagia (esophageal webs), glossitis, iron deficiency anemia
Plummer-Vinson syndrome (may progress to esophageal squamous cell carcinoma)
Elastic skin, hypermobility of joints
Ehlers-Danlos syndrome (collagen defect, usually type III)
Enlarged, hard left supraclavicular node
Virchow's node (abdominal metastasis)
Erythroderma, lymphadenopathy, hepatosplenomegaly, atypical T cells
Sézary syndrome (cutaneous T-cell lymphoma) or mycosis fungoides
Facial muscle spasm upon tapping
Chvostek's sign (hypocalcemia)
Fat, female, forty, and fertile
suggest acute cholelithiasis(bile duct blockage),
cholelithiasis - kamica żółciowa

NOT acute cholecystitis
cholecystitis - zapalenie pęcherzyka żółciowego
Fever, chills, headache, myalgia following antibiotic treatment for syphilis
Jarisch-Herxheimer reaction (rapid lysis of spirochetes results in toxin release)
Fever, cough, conjunctivitis, coryza, diffuse rash

coryza - ostry nieżyt nosa, katar
conjunctivitis - zapalenie spojówek
Measles (Morbillivirus)
Fever, night sweats, weight loss
B symptoms (lymphoma)
Fibrous plaques on soft tissue of penis
Peyronie's disease (connective tissue disorder)
Gout, mental retardation, self mutilating behavior in a boy
Lesch-Nyhan syndrome (HGPRT deficiency, X-linked recessive)
Green-yellow rings around peripheral cornea
Kayser-Fleischer rings (copper accumulation from Wilson's disease)
Hamartomatous GI polyps, hyperpigmentation of mouth/feet/hands
Peutz-Jeghers syndrome (genetic benign polyposis can cause bowel obstruction; Increased cancer risk)
Hepatosplenomealy, osteoporosis, neurological symptoms
Gaucher's disease (glucocerebrosidase deficiency)
Hereditary nephritis, sensorineural hearing loss, cataracts
Alport's syndrome (type IV collagen mutation)
Hypercoagulability (leading to migrating DVTs and vasculitis)
Trousseau's sign (adenocarcinoma of pancreas or lung)
Hyperphagia, hypersexuality, hyperorality, hyperdocility
Klüver-Bucy syndrome (bilateral amygdala lesion)
Hypertension, hypokalemia, metabolic alkalosis
Conn's syndrome
Hypoxemia, polycythemia, hypercapnia
"Blue bloater" (chronic bronchitis: hyperplasia of mucous cells)
Indurated, ulcerated genital lesion
Nonpainful: chancre (primary syphilis, Treponema pallidum)

Painful, with exudate: chancroid (Haemophilus ducreyi)
Infant with failure to thrive, hepatosplenomegaly, neurodegeneration
Niemann-Pick disease (genetic sphingomyelinase deficiency)
Infant with hypoglycemia, failure to thrive, and hepatomegaly
Cori's disease (debranching enzyme deficiency)
Infant with microcephaly, rocker-bottom feet, clenched hands, and structural heart defect
Edwards' syndrome (trisomy 18)
Jaundice, RUQ pain, fever
Charcot's triad 2 (ascending cholangitis)
Keratin pearls on a skin biopsy
Squamous cell carcinoma
Large rash with bull's-eye appearance
Erythema chronicum migrans from Ixodes tick bite (Lyme disease: Borrelia)
Lucid interval after traumatic brain injury
Epidural hematoma (middle meningeal artery rupture)
Male child, recurrent infections, no mature B cells
Bruton's disease (X-linked agammaglobulinemia)
Mucosal bleeding and prolonged bleeding time
Glanzmann's thrombasthenia (defect in platelet aggregation due to lack of Gpllb/llla)
Multiple colon polyps, osteomas/soft tissue tumors, impacted/supernumerary teeth
Gardner's syndrome (subtype of FAP)
Necrotizing vasculitis (lungs) and necrotizing glomerulonephritis
Wegener's (c-ANCA positive) and Goodpasture's syndromes (anti-basement membrane antibodies)
Neonate with arm paralysis following difficult birth
Erb-Duchenne palsy (superior trunk [C5-C6] brachial plexus injury: "waiter's tip")
No lactation postpartum, absent menstruation, cold intolerance
Sheehan's syndrome (pituitary infarction)
Charcot's triad 1 (Nystagmus, intention tremor, scanning speech), bilateral internuclear ophthalmoplegia
Multiple sclerosis
Oscillating slow/fast breathing
Cheyne-Stokes respirations (central apnea in CHF or increased intracranial pressure)
Painful blue fingers/toes, hemolytic anemia
Cold agglutinin disease (autoimmune hemolytic anemia caused by Mycoplasma pneumoniae, infectious mononucleosis)
Painful, pale, cold fingers/toes
Raynaud's syndrome (vasospasm in extremities)
Painful, raised red lesions on palms and soles
Osier's node (infective endocarditis)
Painless erythematous lesions on palms and soles
Janeway lesions (infective endocarditis)
Painless jaundice
Cancer of the pancreatic head obstructing bile duct
Palpable purpura, joint pain, abdominal pain (child)
Henoch-Schonlein purpura (IgA vasculitis affecting skin and kidneys)
Pancreatic, pituitary, parathyroid tumors
Wermer's syndrome (MEN 1)
Pink complexion, dyspnea, hyperventilation
"Pink puffer" (emphysema: centroacinar [smoking], panacinar [a1-antitrypsin deficiency])
Polyuria, acidosis, growth failure, electrolyte imbalances
Fanconi's syndrome (proximal tubular reabsorption defect)
Positive anterior "drawer sign"
Anterior cruciate ligament (ACL) injury
Ptosis, miosis, anhidrosis
Horner's syndrome (sympathetic chain lesion)
Pupil accommodates but doesn't react
Argyll Robertson pupil (neurosyphilis)
Rapidly progressive leg weakness that ascends (following Gl/upper respiratory infection)
Guillain-Barre syndrome (autoimmune acute inflammatory demyelinating polyneuropathy)
Rash on palms and soles
2° syphilis, Rocky Mountain spotted fever, Coxsackievirus A
Recurrent colds, unusual eczema, high serum IgE
Job's syndrome (hyper-lgE syndrome: neutrophil Chemotaxis abnormality)
Red "currant jelly" sputum in alcoholic or diabetic patients
Klebsiella pneumoniae
Red, itchy, swollen rash of nipple/areola
Paget's disease of the breast (represents underlying neoplasm)
Red urine in the morning, fragile RBCs
Paroxysmal nocturnal hemoglobinuria
Renal cell carcinoma, hemangioblastomas, angiomatosis, pheochromocytoma
von Hippel-Lindau disease (dominant tumor suppressor gene mutation)
Resting tremor, rigidity, akinesia, postural instability
Parkinson's disease (nigrostriatal dopamine depletion)
Restrictive cardiomyopathy (juvenile form:cardiomegaly), exercise intolerance
Pompe's disease (lysosomal glucosidase deficiency)
Retinal hemorrhages with pale centers
Roth's spots (bacterial endocarditis)
Severe jaundice in neonate
Crigler-Najjar syndrome (congenital unconjugated hyperbilirubinemia)
Severe RLQ pain with rebound tenderness
McBurney's sign (appendicitis)
Short stature, increased incidence of tumors/leukemia, aplastic anemia

stature - postura człowieka
Fanconi's anemia (genetically inherited; often progresses to AML)
Single palm crease
Simian crease (Down syndrome)
Situs inversus, chronic sinusitis, bronchiectasis
Kartageners syndrome (dynein defect affecting cilia)
Skin hyperpigmentation
Addison's disease (1 ° adrenocortical insufficiency of autoimmune or infectious etiology)
Slow, progressive muscle weakness in boys
Becker's muscular dystrophy (X-linked, defective dystrophin; less severe than Duchenne's)
Small, irregular red spots on buccal/lingual mucosa with blue-white centers
Koplik spots (measles)
Smooth, flat, moist white lesions on genitals
Condylomata lata (2° syphilis)
Splinter hemorrhages in fingernails
Bacterial endocarditis
"Strawberry tongue"
Scarlet fever, Kawasaki disease, toxic shock syndrome
Streak ovaries, congenital heart disease, horseshoe kidney
Turner syndrome (XO, short stature, webbed neck, lymphedema)
Sudden swollen/painful big toe joint, tophi
Gout/podagra (hyperuricemia)
Swollen gums, mucous bleeding, poor wound healing, spots on skin
Scurvy (vitamin C deficiency: can't hydroxylate proline/lysine for collagen synthesis)
Swollen, hard, painful finger joints
Osteoarthritis (osteophytes on PIP [Bouchard's nodes], DIP [Heberden's nodes])
Systolic ejection murmur
(crescendo-decrescendo)
Aortic valve stenosis
Thyroid and parathyroid tumors, pheochromocytoma
Sipple's syndrome (MEN 2A)
Toe extension/fanning upon plantar scrape
Babinski's sign (UMN lesion)
Unilateral facial drooping involving forehead
Bell's palsy (LMN CN VII palsy)
Urethritis, conjunctivitis, arthritis in a male
Reiter's syndrome (reactive arthritis associated with HLA-B27)
Vascular birthmark (port-wine stain)
Hemangioma (benign, but associated with Sturge-Weber syndrome)
Vasculitis from exposure to endotoxin causing glomerular thrombosis
Shwartzman reaction (following second exposure to endotoxin)
Vomiting blood following esophagogastric lacerations
Mallory-Weiss syndrome (alcoholic and bulimic patients)
"Waxy" casts with very low urine flow
Chronic end-stage renal disease
WBC casts in urine
Acute pyelonephritis
Weight loss, diarrhea, arthritis, fever, adenopathy
Whipple's disease (Tropheryma whippelii)
"Worst headache of my life"
Subarachnoid hemorrhage (the most common cause of spontaneous, nontraumatic SAH is a ruptured berry aneurysm)