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115 Cards in this Set

  • Front
  • Back
Abdominal pain, ascites, hepatomegaly
Budd-Chiari syndrome (posthepatic venous thrombosis)
Achilles tendon xanthoma
Familial hypercholesterolemia
Adrenal hemorrhage, hypotension, DIC
Waterhouse-Friderichsen syndrome (meningococcemia)
Arachnodactyly, lens dislocation, aortic dissection, hyperflexible joints
Marfan’s syndrome (fibrillin defect)
Back pain, fever, night sweats, weight loss
Pott’s disease (vertebral tuberculosis)
Big toe extension/fanning upon plantar scrape
Babinski’s sign (UMN lesion)
Bilateral hilar adenopathy, uveitis
Sarcoidosis (noncaseating granulomas)
Blue sclera
Osteogenesis imperfecta (collagen defect)
Bluish line on gingiva
Burton’s line (lead poisoning)
Bone pain, bone enlargement, arthritis
Paget’s disease of bone ( increased osteoblastic and osteoclastic activity)
Café-au-lait spots, Lisch nodules (iris hamartomas)
Neurofibromatosis type I (bilateral acoustic neuromas = type II)
Calf pseudohypertrophy
Muscular dystrophy (most commonly Duchenne’s)
“Cherry-red spot” on macula
Tay-Sachs (ganglioside accumulation) or Niemann-Pick (lysosomal storage disease)
Chest pain, pericardial effusion/friction rub, persistent fever following MI
Dressler’s syndrome (autoimmune-mediated post-MI fibrinous pericarditis)
Child uses arms to stand up from squat
Gowers’ sign (Duchenne muscular dystrophy: X-linked recessive deleted dystrophin gene)
Child with fever develops red rash on face that spreads to the body
“Slapped cheeks” (erythema infectiosum/fifth disease: parvovirus B19)
Chorea, dementia, caudate degeneration
Huntington’s disease (autosomal-dominant CAG repeat expansion)
Chronic exercise intolerance with myalgia, fatigue, painful cramps
McArdle’s disease (muscle phosphorylase deficiency)
Cold intolerance
Hypothyroidism
Conjugate lateral gaze palsy, horizontal diplopia
Internuclear ophthalmoplegia (damage to MLF; bilateral [multiple sclerosis], unilateral [stroke])
Continuous “machinery” heart murmur
PDA (close with indomethacin; open with misoprostol)
Cutaneous/dermal edema due to connective tissue deposition
Myxedema (hypothyroidism, Graves’ disease)
Dark purple skin/mouth nodules
Kaposi’s sarcoma (usually AIDS patients [gay men]: associated with HHV-8)
Deep, labored breathing/hyperventilation
Kussmaul breathing (diabetic ketoacidosis)
Dermatitis, dementia, diarrhea
Pellagra (niacin [vitamin B3] deficiency)
Dilated cardiomyopathy, edema, polyneuropathy
Wet beriberi (thiamine [vitamin B1] deficiency)
Dog or cat bite resulting in infection
Pasteurella multocida
Dry eyes, dry mouth, arthritis
Sjögren’s syndrome (autoimmune destruction of exocrine glands)
Dysphagia (esophageal webs), glossitis, iron deficiency anemia
Plummer-Vinson syndrome (may progress to esophageal squamous cell carcinoma)
Elastic skin, hypermobility of joints
Ehlers-Danlos syndrome (collagen defect)
Enlarged, hard left supraclavicular node
Virchow’s node (abdominal metastasis)
Erythroderma, lymphadenopathy, hepatosplenomegaly, atypical T cells
Sézary syndrome (cutaneous T-cell lymphoma) or mycosis fungoides
Facial muscle spasm upon tapping
Chvostek’s sign (hypocalcemia)
Fat, female, forty, and fertile
Acute cholecystitis (bile duct blockage)
Fever, chills, headache, myalgia following antibiotic treatment for syphilis
Jarisch-Herxheimer reaction (rapid lysis of spirochetes results in toxin release)
Fever, cough, conjunctivitis, coryza, diffuse rash
Measles (Morbillivirus)
Fever, night sweats, weight loss
B symptoms (lymphoma)
Fibrous plaques in soft tissue of penis
Peyronie’s disease (connective tissue disorder)
Gout, mental retardation, self-mutilating behavior in a boy
Lesch-Nyhan syndrome (HGPRT deficiency)
Green-yellow rings around peripheral cornea
Kayser-Fleischer rings (copper accumulation from Wilson’s disease)
Hamartomatous GI polyps, hyperpigmentation of mouth/feet/hands
Peutz-Jeghers syndrome (genetic benign polyposis can cause bowel obstruction; increased cancer risk)
Hepatosplenomegaly, osteoporosis, neurologic symptoms
Gaucher’s disease (glucocerebrosidase deficiency)
Hereditary nephritis, sensorineural hearing loss, cataracts
Alport’s syndrome (collagen mutation)
Hypercoagulability (leading to migrating DVTs and vasculitis)
Trousseau’s sign (adenocarcinoma of pancreas or lung)
Hyperphagia, hypersexuality, hyperorality, hyperdocility
Klüver-Bucy syndrome (bilateral amygdala lesion)
Hypertension, hypokalemia, metabolic acidosis
Conn’s syndrome (Primaryhyperaldosteronism)
acidosis
Hypoxemia, polycythemia, hypercapnia
“Blue bloater” (chronic bronchitis: hyperplasia of mucous cells)
Indurated, ulcerated genital lesion (nonpainful)
Chancre (Primarysyphilis: Treponema pallidum)
Infant with failure to thrive, hepatosplenomegaly, neurodegeneration
Niemann-Pick disease (genetic sphingomyelinase deficiency)
Infant with hypoglycemia, failure to thrive, and hepatomegaly
Cori’s disease (debranching enzyme deficiency)
Infant with microcephaly, rocker-bottom feet, and structural heart defect
Edwards’ syndrome (trisomy 18)
Jaundice, RUQ pain, fever
Charcot’s triad 2 (ascending cholangitis)
Keratin pearls on a skin lesion
Squamous cell carcinoma
Large rash with bull’s-eye appearance
Erythema chronicum migrans from tick bite (Lyme disease: Borrelia)
Lucid interval after traumatic brain injury
Epidural hematoma
Male child, recurrent infections, no mature B cells
Bruton’s disease (X-linked agammaglobulinemia)
Mucosal bleeding and prolonged bleeding time
Glanzmann’s thrombasthenia (defect in platelet aggregation due to lack of GpIIb/IIIa)
Multiple colon polyps, osteomas/soft tissue tumors, impacted/supernumerary teeth
Gardner’s syndrome (genetic disorder, predisposes to colon cancer)
Necrotizing vasculitis (lungs) and necrotizing glomerulonephritis
Wegener’s and Goodpasture’s syndromes (hemoptysis and glomerular disease)
Neonate with arm paralysis following difficult birth
Erb-Duchenne palsy (superior trunk [C5–C6] brachial plexus injury: “waiter’s tip”)
No lactation postpartum, absent menstruation, cold intolerance
Sheehan’s syndrome (pituitary infarction)
Nystagmus, intention tremor, scanning speech
Charcot’s triad 1 (multiple sclerosis)
Oscillating slow/fast breathing
Cheyne-Stokes respirations (central apnea in CHF or increased intracranial pressure)
Painful blue fingers/toes, hemolytic anemia
Cold agglutinin disease (autoimmune hemolytic anemia caused by Mycoplasma pneumonia, infectious mononucleosis)
Painful, pale, cold fingers/toes
Raynaud’s syndrome (vasospasm in extremities)
Painful, raised red lesions on palms and soles
Osler’s node (infective endocarditis)
Painless jaundice
Cancer of the pancreatic head obstructing bile duct
Palpable purpura, joint pain, abdominal pain (child)
Henoch-Schönlein purpura (IgA vasculitis affecting skin and kidneys)
Pancreatic, pituitary, parathyroid tumors
Wermer’s syndrome (MEN 1)
Pink complexion, dyspnea, hyperventillation
“Pink puffer” (emphysema: centroacinar [smoking], panacinar [1-antitrypsin deficiency])
Polyostotic fibrous dysplasia, precocious puberty, café-au-lait spots, short stature in a young girl
McCune-Albright syndrome (mosaic G-protein signaling mutation)
Polyuria, acidosis, growth failure, electrolyte imbalances
Fanconi’s syndrome (proximal tubular reabsorption defect)
Positive anterior “drawer sign”
Anterior cruciate ligament (ACL) injury
Ptosis, miosis, anhidrosis
Horner’s syndrome (sympathetic chain lesion)
Pupil accommodates but doesn’t react
Argyll Robertson pupil (neurosyphilis)
Rapidly progressive leg weakness that ascends (following GI/upper respiratory infection
Guillain-Barré syndrome (autoimmune acute inflammatory demyelinating polyneuropathy)
Rash on palms and soles
Secondarysyphilis, Rocky Mountain spotted fever
Recurrent colds, unusual eczema, high serum IgE
Job’s syndrome (hyper-IgE syndrome: neutrophil chemotaxis abnormality)
Red “currant jelly” sputum
Klebsiella pneumoniae
Red, itchy, swollen rash of nipple/areola
Paget’s disease of the breast (represents underlying neoplasm)
Red urine in the morning
Paroxysmal nocturnal hemoglobinuria
Renal cell carcinoma, hemangioblastomas, angiomatosis, pheochromocytoma
von Hippel–Lindau disease (dominant tumor suppressor gene mutation)
Resting tremor, rigidity, akinesia, postural instability
Parkinson’s disease (nigrostriatal dopamine depletion)
Restrictive cardiomyopathy (juvenile form: cardiomegaly), exercise intolerance
Pompe’s disease (lysosomal glucosidase deficiency)
Retinal hemorrhages with pale centers
Roth’s spots (bacterial endocarditis)
Severe jaundice in neonate
Crigler-Najjar syndrome (congenital unconjugated hyperbilirubinemia)
Severe RLQ pain with rebound tenderness
McBurney’s sign (appendicitis)
Short stature, increased incidence of tumors/ leukemia, aplastic anemia
Fanconi’s anemia (genetically inherited; often progresses to AML)
Single palm crease
Simian crease (Down syndrome)
Situs inversus, chronic sinusitis, bronchiectasis
Kartagener’s syndrome (dynein defect affecting cilia)
Skin hyperpigmentation
Addison’s disease (Primary adrenocortical insufficiency of autoimmune or infectious etiology)
Slow, progressive muscle weakness in boys
Becker’s muscular dystrophy (X-linked, defective dystrophin; less severe than Duchenne’s)
Small, irregular red spots on buccal/lingual mucosa with blue-white centers
Koplik spots (measles)
Small, nontender, erythematous lesions on palms/soels
Janeway lesions (infective endocarditis)
on palms/soles
Smooth, flat, moist white lesions on genitals
Condylomata lata (Secondary syphilis)
Splinter hemorrhages in fingernails
Bacterial endocarditis
“Strawberry tongue”
Scarlet fever, Kawasaki disease, toxic shock syndrome
Streak ovaries, congenital heart disease, horseshoe kidney
Turner’s syndrome (XO, short stature, webbed neck, lymphedema)
Sudden swollen/painful big toe joint, tophi
Gout/podagra (hyperuricemia)
Swollen gums, mucous bleeding, poor wound healing, spots on skin
Scurvy (vitamin C deficiency: can’t hydroxylate proline/lysine for collagen synthesis)
Swollen, hard, painful finger joints
Osteoarthritis (osteophytes on PIP [Bouchard’s nodes], DIP [Heberden’s nodes])
Systolic ejection murmur (crescendo-decrescendo)
Aortic valve stenosis
Thyroid, parathyroid, adrenal tumors
Sipple’s syndrome (MEN 2A)
Ulcerated genital lesion with exudate (painful)
Chancroid (Haemophilus ducreyi )
Unilateral facial drooping
Bell’s palsy (LMN CN VII palsy)
Urethritis, conjunctivitis, arthritis in a male
Reiter’s syndrome (reactive arthritis associated with HLA-B27)
Vascular birthmark (port-wine stain)
Hemangioma (benign, but associated with Sturge-Weber syndrome)
Vasculitis from exposure to endotoxin causing glomerular thrombosis
Shwartzman reaction (following second exposure to endotoxin)
Vomiting blood following esophagogastric lacerations
Mallory-Weiss syndrome (alcoholics and eating disorders)
“Waxy” casts with very low urine flow
Chronic end-stage renal disease
WBC casts in urine
Acute pyelonephritis or cystitis
Weight loss, diarrhea, arthritis, fever, adenopathy
Whipple’s disease (Tropheryma whippelii )
“Worst headache of my life”
Berry aneurysm (associated with adult polycystic kidney disease)