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13 Cards in this Set

  • Front
  • Back
2 reasons why sodium movement predominates potassium.
1. Sodium channels open faster.
2. Higher Na+ driving force.`
5 components of sodium channel voltage gates.
1. Activation gate
2. Inactivation gate
3. Conductance pore
4. Selectivity filter
5. Voltage sensor
Calcium's effect on voltage gated channels.
increases threshold and stabilizes membrane
Tetradotoxin's effect on voltage gated channels.
blocks sodium channels on extracellular side
Local anesthesia's effect on voltage gated channels.
insert in conductance pore and block sodium perm. increase
Batrachtotoxin's effect on voltage gated channels.
irreversibly opens sodium channels
Scorpion Toxin's effect on voltage gated channels.
blocks opening of Potassium channels
TEA's effect on voltage gated channels.
blocks voltage gated K+ channels from intracellular side
What direction is antidromic?
Orthodromic?
Antidromic= toward cell body
Orthodromic= toward axon terminal
2 ways to increase conduction velocity along axon.
1. Increase diameter of axon
2. Reduce short-circuiting across membrane (myelination)
Name for myelination in PNS and CNS.
PNS- schwann cells
CNS- oligodendrocytes
Name for break between glial cells (myelination)
Nodes of Ranvier
What type of conduction is involved in myelinated cells?
Saltatory conduction