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67 Cards in this Set
- Front
- Back
Cell
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Basic building block for the human body.
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How many types of cells in the human body?
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200
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Squamos cell
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Thin, flat and cover surfaces (like skin) or line the esophagus or other tubes.
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Cuboidal
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Square. Ex. Liver cells
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Spheroid
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Egg cells (ova) and fat cells are round or oval.
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Columnar
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Taller than they are wide. They line the intestines. Have an increased surface area.
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Fusiform
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Cells that are thick in the middle and tapered toward the ends. Smooth muscle cells are fusiform.
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Stellate cells
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"star shaped" cells
Ex. nerve cells |
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Modern cell theory was based on the work of these men.
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Robert Hook
Theodore Schwann Louis Pasteur |
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Modern cell theory
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-all organisms are composed of cells and cell products.
-cell is the simplest structural and functional unit of life. -all functions and structures are ultimately due to the activitites of cells -cells come only from pre-existing cells -cells of all species have many fundamental similarities |
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Surrounded by a plasma membrane, made up of proteins and lipids
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Cells
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Cell membrane
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-bilayer of lipids with diverse protein embedded in it.
98% if membrane molecules are lipids. -75% of those lipids are phospholipids -hydrophilic heads facing the water on each side of the cell membrane. -membrane is dynamic and "fluid" |
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Make up about 50% of cell membrane weight.
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Proteins
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Target site for many pharmaceutical agents.
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Cell membrane
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Channel proteins
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molecules have "pores" adn allow passage of water and other solutes through the membrane.
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Carriers
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"pumps" - actively transport molecules into the cell utilizing ATP in the process
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Glycocalyx
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"fuzzy" coat external to the plasma. It acts like an identification tag that enables the body to distinguish healthy cells from transplanted tissues, invading organisms,and diseased cells.
MCH1-major histocompatibility complex |
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Microvilli
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extensions fo the plasm membrane that serve primarily to increase the cell's surface area.
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Cilia
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hair-like processes that project from the surface of the cell.
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Motile cilia
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In respiratory tract and fallopian tubes. They "wave" and help move materials through the tubes.
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Flagella
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single whip-like structure much larger than cilia. Only functional flagella is the tail of the sperm cell.
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Cytoplasm
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fluid that is contained inside the plasma membrane. Has a supportive framework called cytoskeleton.
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Intracellular fluid (ICP)
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Clear gel in the cytoplasm
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Nucleus
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Structure at the center of the cell. Contains all genetic information. These codes are in the form of nucleic acids.
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Plasma membrane
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Barrier and gateway between the cytoplasm and the extracellular fluid.
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Passive transport
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-does NOT use energy
-will occur on its own -filtration, diffusion, osmosis |
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Active transport
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-require ATP
-active transport and vesicular transport. |
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Filtration
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process by which particles are driven through a filter, or a selectively permeable membrane by hydrostatic pressure.
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Hydrostatic pressure
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Pressure exerted on a membrane by water.
(stacks water on a molecule and the weight forces it through the cell membrane) |
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Simple diffusion
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Net movement of particles from an area of higher concentration to an area of lower concentration.
Occurs in air or water and does not include a plasma membrane.(semi permeable) |
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Concentration gradient
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Concentration of a substance differs from one point to another.
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Semi permeable (selectively permeable) membrane
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Molecules will diffuse through it if the membrane is permeable to that substance.
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Diffusion rates
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- Higher temp = faster diffusion
- Heavy molecules = slower - Higher concentration difference = faster - More surface area = faster |
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Facilitated diffusion
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A solute binds to a transporter on one side of membrane, and then releases on other side of membrane.
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Osmosis
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Diffusion of water through a selectively permeable membrance, from area of higher water concentration to lower.
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Tonicity
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Ability of a solution to affect the fluid volume and pressure in a cell.
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Hypotonic solution
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Lower concentration of nonpermeating solutes than in the ICF. Cells will absorb water, swell, and burst.
Ex. Distilled water |
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Hypertonic solution
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Higher concentration of nonpermeating solutes than the ICF. Cells will lose water and shrivel.
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Isotonic solution
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Concentration of solutes is Equal to ICF.
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Active transport
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Carrier-mediated transport of a solute through a plasma membrane, but AGAINST a concentration gradient.
Uses ATP and energy. -from an area of low conentration to high (opposite to diffusion) |
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Sodium-potassium pump
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Keeps K+ concentration higher and Na+ lower in the cell.
Ex of active transport Exchanges 3 Na+ atoms for 2 K+ atoms. Consumption of 1 ATP molecule. |
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Important part of the nerve impulses and cardiac function.
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Sodium-potassium pump
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Vesicular transport
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Moves large particles and droplets of fluid, or numerous molecules through the plasma membrane all at once.
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Endocytosis
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Vesicular transport processes that bring matter INTO the cell.
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Excocytosis
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Vesicular transport processes that RELEASE matter from the cell.
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Phagocytosis
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"Cell eating" -process of engulfing particles such as bacteria, dust, cell debris.
-Common to "defense" cells like monocytes in the IMMUNE SYSTEM. |
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Pinocytosis
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"Cell drinking" - taking in droplets of ECF, which contain molecules that are used by cells.
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Membranous organelles
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Nucleus, mitochondria, lysosomes, endoplasmic reticulum, golfo complex
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Non-membranous organelles
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Ribosomes
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Nucleus
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Largest organelle
Spheroid in shape |
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Nucleoplasm
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Material inside nucleus.
-chromatin (DNA and protein) -nucleoli (produce ribosomes) |
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Endoplasmic reticulum
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"little network within the cytoplasm"
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Endoplasmic reticulum
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System of interconnected channels that extend through cytoplasm and reach the nuclear membrane.
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Rough Endoplasmic reticulum
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The channels are covered with Ribosome, which synthesize proteins.
-Most abundant in cells that produce large amts of protein, such as digestive glands. |
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Smooth Endoplasmic reticulum
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Synthesizes steroids and lipids.
-responsible for detoxifying alchohol (ETOH) and other drugs. |
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Smooth Endoplasmic reticulum
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Found in skeletal and cardiac muscle, that store calcium adn release it to trigger muscle contraction.
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Ribosomes
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Small granules of protein and RNA found in cytoplasm.
-Function: Protein synthesis -Assemble amino acids specified by messenger RNA codes. |
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Golgi complex
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Synthesize carbohydrates and put finishing touches on protein and glycoprotein synthesis.
-Function - packages proteins into membrane-bound Golgi Vesicles. |
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Lysosomes
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-Produced by Gogli complex
-hydrolyze or digest proteins, nucleic acids, complex carbs, phospholipids. -involve Autophagy |
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Autophagy
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Digestion of surplus cells by their own lysosomal enzymes. (the cell consumes itself)
-Ex. As in contents of liver |
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Peroxisomes
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-Not produced by Golgi complex
-Neutralize free radicals -Produce hydrogen peroxide as a byproduct of metabolism. |
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Mitochondria
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"power-house" of cells
-bean-shaped -in cardiac and skeletal muscle -generates most the the cell's ATP |
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Centrioles
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Play a role in cell division (mitosis)
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Cytoskeleton
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Collection of protein filiaments and cylinders that determine the SHAPE of the cell. Main function is support.
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Inclusions
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Stored cellular products (glycogen or fat deposits) OR foreign bodies (dust).
-NO unit membrane -NOT essential to cell survival. |
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Mitosis
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Process by which cells divide to grow or to repair damage.
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4 phases of mitosis
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-Prophase: Condensing of chromatin fibers into chromatid pairs
-Metaphase: Pairs line up along metaphase plate. -Anaphase: Centromeres split, identical sets move to opposite sides of cell. -Telophase: Nucleoli reappear around 2 new sets of chromosomes and cell begins to split for cytokinesis. |