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67 Cards in this Set

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Cell
Basic building block for the human body.
How many types of cells in the human body?
200
Squamos cell
Thin, flat and cover surfaces (like skin) or line the esophagus or other tubes.
Cuboidal
Square. Ex. Liver cells
Spheroid
Egg cells (ova) and fat cells are round or oval.
Columnar
Taller than they are wide. They line the intestines. Have an increased surface area.
Fusiform
Cells that are thick in the middle and tapered toward the ends. Smooth muscle cells are fusiform.
Stellate cells
"star shaped" cells
Ex. nerve cells
Modern cell theory was based on the work of these men.
Robert Hook
Theodore Schwann
Louis Pasteur
Modern cell theory
-all organisms are composed of cells and cell products.
-cell is the simplest structural and functional unit of life.
-all functions and structures are ultimately due to the activitites of cells
-cells come only from pre-existing cells
-cells of all species have many fundamental similarities
Surrounded by a plasma membrane, made up of proteins and lipids
Cells
Cell membrane
-bilayer of lipids with diverse protein embedded in it.
98% if membrane molecules are lipids.
-75% of those lipids are phospholipids
-hydrophilic heads facing the water on each side of the cell membrane.
-membrane is dynamic and "fluid"
Make up about 50% of cell membrane weight.
Proteins
Target site for many pharmaceutical agents.
Cell membrane
Channel proteins
molecules have "pores" adn allow passage of water and other solutes through the membrane.
Carriers
"pumps" - actively transport molecules into the cell utilizing ATP in the process
Glycocalyx
"fuzzy" coat external to the plasma. It acts like an identification tag that enables the body to distinguish healthy cells from transplanted tissues, invading organisms,and diseased cells.
MCH1-major histocompatibility complex
Microvilli
extensions fo the plasm membrane that serve primarily to increase the cell's surface area.
Cilia
hair-like processes that project from the surface of the cell.
Motile cilia
In respiratory tract and fallopian tubes. They "wave" and help move materials through the tubes.
Flagella
single whip-like structure much larger than cilia. Only functional flagella is the tail of the sperm cell.
Cytoplasm
fluid that is contained inside the plasma membrane. Has a supportive framework called cytoskeleton.
Intracellular fluid (ICP)
Clear gel in the cytoplasm
Nucleus
Structure at the center of the cell. Contains all genetic information. These codes are in the form of nucleic acids.
Plasma membrane
Barrier and gateway between the cytoplasm and the extracellular fluid.
Passive transport
-does NOT use energy
-will occur on its own
-filtration, diffusion, osmosis
Active transport
-require ATP
-active transport and vesicular transport.
Filtration
process by which particles are driven through a filter, or a selectively permeable membrane by hydrostatic pressure.
Hydrostatic pressure
Pressure exerted on a membrane by water.
(stacks water on a molecule and the weight forces it through the cell membrane)
Simple diffusion
Net movement of particles from an area of higher concentration to an area of lower concentration.
Occurs in air or water and does not include a plasma membrane.(semi permeable)
Concentration gradient
Concentration of a substance differs from one point to another.
Semi permeable (selectively permeable) membrane
Molecules will diffuse through it if the membrane is permeable to that substance.
Diffusion rates
- Higher temp = faster diffusion
- Heavy molecules = slower
- Higher concentration difference = faster
- More surface area = faster
Facilitated diffusion
A solute binds to a transporter on one side of membrane, and then releases on other side of membrane.
Osmosis
Diffusion of water through a selectively permeable membrance, from area of higher water concentration to lower.
Tonicity
Ability of a solution to affect the fluid volume and pressure in a cell.
Hypotonic solution
Lower concentration of nonpermeating solutes than in the ICF. Cells will absorb water, swell, and burst.
Ex. Distilled water
Hypertonic solution
Higher concentration of nonpermeating solutes than the ICF. Cells will lose water and shrivel.
Isotonic solution
Concentration of solutes is Equal to ICF.
Active transport
Carrier-mediated transport of a solute through a plasma membrane, but AGAINST a concentration gradient.
Uses ATP and energy.
-from an area of low conentration to high (opposite to diffusion)
Sodium-potassium pump
Keeps K+ concentration higher and Na+ lower in the cell.
Ex of active transport
Exchanges 3 Na+ atoms for 2 K+ atoms.
Consumption of 1 ATP molecule.
Important part of the nerve impulses and cardiac function.
Sodium-potassium pump
Vesicular transport
Moves large particles and droplets of fluid, or numerous molecules through the plasma membrane all at once.
Endocytosis
Vesicular transport processes that bring matter INTO the cell.
Excocytosis
Vesicular transport processes that RELEASE matter from the cell.
Phagocytosis
"Cell eating" -process of engulfing particles such as bacteria, dust, cell debris.
-Common to "defense" cells like monocytes in the IMMUNE SYSTEM.
Pinocytosis
"Cell drinking" - taking in droplets of ECF, which contain molecules that are used by cells.
Membranous organelles
Nucleus, mitochondria, lysosomes, endoplasmic reticulum, golfo complex
Non-membranous organelles
Ribosomes
Nucleus
Largest organelle
Spheroid in shape
Nucleoplasm
Material inside nucleus.
-chromatin (DNA and protein)
-nucleoli (produce ribosomes)
Endoplasmic reticulum
"little network within the cytoplasm"
Endoplasmic reticulum
System of interconnected channels that extend through cytoplasm and reach the nuclear membrane.
Rough Endoplasmic reticulum
The channels are covered with Ribosome, which synthesize proteins.
-Most abundant in cells that produce large amts of protein, such as digestive glands.
Smooth Endoplasmic reticulum
Synthesizes steroids and lipids.
-responsible for detoxifying alchohol (ETOH) and other drugs.
Smooth Endoplasmic reticulum
Found in skeletal and cardiac muscle, that store calcium adn release it to trigger muscle contraction.
Ribosomes
Small granules of protein and RNA found in cytoplasm.
-Function: Protein synthesis
-Assemble amino acids specified by messenger RNA codes.
Golgi complex
Synthesize carbohydrates and put finishing touches on protein and glycoprotein synthesis.
-Function - packages proteins into membrane-bound Golgi Vesicles.
Lysosomes
-Produced by Gogli complex
-hydrolyze or digest proteins, nucleic acids, complex carbs, phospholipids.
-involve Autophagy
Autophagy
Digestion of surplus cells by their own lysosomal enzymes. (the cell consumes itself)
-Ex. As in contents of liver
Peroxisomes
-Not produced by Golgi complex
-Neutralize free radicals
-Produce hydrogen peroxide as a byproduct of metabolism.
Mitochondria
"power-house" of cells
-bean-shaped
-in cardiac and skeletal muscle
-generates most the the cell's ATP
Centrioles
Play a role in cell division (mitosis)
Cytoskeleton
Collection of protein filiaments and cylinders that determine the SHAPE of the cell. Main function is support.
Inclusions
Stored cellular products (glycogen or fat deposits) OR foreign bodies (dust).
-NO unit membrane
-NOT essential to cell survival.
Mitosis
Process by which cells divide to grow or to repair damage.
4 phases of mitosis
-Prophase: Condensing of chromatin fibers into chromatid pairs
-Metaphase: Pairs line up along metaphase plate.
-Anaphase: Centromeres split, identical sets move to opposite sides of cell.
-Telophase: Nucleoli reappear around 2 new sets of chromosomes and cell begins to split for cytokinesis.