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26 Cards in this Set

  • Front
  • Back

thyroid gland

Largest major endocrine gland that exclusively produces hormones




Only endocrine gland that stores its hormones (thyroid hormone); 2-3 month's worth raw, unfinished supply




2 kinds of cells


1. follicular cells- produce thyroid hormone (TH); Thyroglobulin


2. Parafollicular cells- produce calcitonin

Structure of thyroid hormones

2 tyrosine bound together


T4 has 4 iodines; T3 has 3 (ONLY structural difference btwn them)

Calcium regulation

1. Calcitonin- responds to too much calcium in blood; stimulates calcium salt deposit in bone. Released by parafollicular cells of thyroid gland




2. Parathyroid hormone (PTH)- released by parathyroid glands. Responds to humoral stimulus (low blood [Ca]). Releases HCl and osteoclasts to degrade bone matrix and release Ca into the blood

Adrenal cortex

Produces steroids- use direct gene activation


3 layers


1. zona glomerulosa- outermost layer. Produces mineralocorticoids- regulate mineral balance. Mainly aldosterone- Na regulation; indirectly affects water regulation, raises BP by stimulating Na reabsorption


2. Zona fasciculata- produces glucocorticoids. Regulate blood sugar. Mainly cortisol


3. Zona reticularis- produces weak androgens

Result of long-term stress

Excess aldosterone --> increased BP


Excess cortisol --> weakened immune system

adrenal medulla

Produces amines- epinephrine and norepinephrine.




Short-term response to stress

Pancreas

99% of cells are part of GI system; secrete digestive enzymes. Acing cells and exocrine gland (ducts)


1% of cells have endocrine function: Islets of Langerhans, aka pancreatic islets. 2 kinds of cells


1. alpha cells- produce glucagon; raises BG


2. beta cells- produce insulin- lowers BG

BG regulation

If BG rises (humoral stimulus), beta cells produce insulin. Stimulates body tissues to take glucose in from blood, lowers BG. Liver takes up glucose from blood and stores it as glycogen.




If BG low, alpha cells produce glucagon. Stimulates glycogen breakdown (glycogenolysis), increases BG.

Pineal gland

Located in brain




Releases melatonin- sleep regulation. Melatonin cycle allows for periods of rest and activity. Levels are high at night and low during the day.

Thymus

Hormones do not circulate




Thymic hormones affect thymus and T cells

Functions of reproductive system

Latest maturing system




1. production of gametes (eggs, sperm)


2. secretion of sex hormones


3. production of offspring


4. nurturing of offspring (female- mammary glands)

Primary sex organs

Gonads


Testes in males


Ovaries in females


Produce gametes and sex hormones

Accessory reproductive organs

Ducts


Glands


Supportive Structures

Testes

Primary sex organ of male reproductive system


Produce sperm and male sex hormone (testosterone)


Seminiferous tubules=where sperm is formed. 2 kinds of cells:


1. spermatogenic cells- cells that will develop into sperm


2. Sertoli cells- nourish the spermatogenic cells (provide appropriate nutrients and environment)




3rd type of cell in testes=Leydig cells. Produce testosterone.

Male accessory reproductive organs

1. ducts- transport, storage, maturation of sperm


a. epididymus (swimming lessons)


b. vas deferens


c. ejaculatory duct


d. urethra




2. glands- secrete seminal fluid


a. seminal vessicles- add fluids and nutrients


b. prostate gland- adds different fluid to sperm


c. bulbourethral gland- adds last component of


seminal fluid




3. supporting structures


a. scrotum- sac which holds testes and


epididymis outside of body; aids in testes


temperature regulation


b. penis


semen

sperm+seminal fluid

diploid (2n)



chromosome number in most body cells (46 in humans)

haploid (n)

chromosome number in gametes (23 in humans)

karyotype

ordered display of all the chromosomes in the body cells

meiosis

cell division that produces gametes


occurs in the gonads


results in 4 different haploid gametes

Spermatogenesis

Process that produces sperm in testes.


Takes 3 months (beginning to end)


1. meiosis --> haploid cells


2. spermiogenesis (haploid cells -->sperm)


a. 2n stem cell=spermatogonium


b. mitosis --> 2 diploid cells (primary spermatocytes)


c. meiosis I --> 2 haploid cells (secondary spermatocytes)


d. meiosis II --> 4 haploid cells (spermatids)

Sperm

1. Head- acrosome (has digestive enzymes); nucleus (haploid # chromosomes)


2. Middle piece/neck- mitochondria (provides energy to swim)


3. Tail- flagella (organelle which allows sperm to swim)

Hypothalamus (in regards to male reproduction)

Makes GnRH- stimulates AP to release LH and FSH


LH stimulates Leydig cells to produce testosterone


FSH targets Sertoli cells to secrete androgen-binding protein (ABP)

effects of testosterone

1. growth of repro organs


2. male secondary sex characteristics


3. stimulates spermatogenesis


4. growth spurt


5. sex drive

Female reproductive system

1. female gonads=ovaries. Produce eggs and sex hormones.


2. accessory repro organs


a. ducts- fallopian tubes, uterus, vagina


b. mammary glands

Layers of the uterine wal

1. Perimetrium- visceral peritoneum


2. Myometrium- smooth muscle layer


3. Endometrium- mucous memrans


a. stratum basalis- permanent layer


b. stratum functionalis- changes in response to


sex hormones