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75 Cards in this Set

  • Front
  • Back
Organs of digestion
  1. mouth
  2. pharynx (throat)
  3. esophagus
  4. stomach
  5. small intestine
  6. large intestine
Accessory organs of digestion
  1. teeth
  2. tongue
  3. salivary glands
  4. liver
  5. gallbladder
  6. pancreas
Digestion definition
process of breaking down food by mechanical and chemical action to be used by the body
Review eating process
  • chewing
  • enzymes & HCL stim
  • pharynx
  • lower esophageal sphincter
  • Pepsin digest protein
  • pyloric sphincter
  • SmI - bicarbonate, bile, amylase, protease, lipase
  • absorption
  • colon
  • absoprtion
  • elimination
Sign & Sympton of low HCL
can't build muscle
What nutrients NOT absorbed in duedenum
  • fat soluble vitamins
  • chloride
  • simple sugars
  • fatty acids
  • amino acids
  • cholesterol
  • Vit K
  • B12
  • electrolytes
  • bile salts
HOw long for baby gut to close
6 months - 2 years
Low HCL affects
  • Pepsin not released = poor protein digest
    = poor absorption
    = high allergy and immune responce
  • Poor peristalsis = poor elim, retox
  • Poor mucus = ulcer
  • poor intrinsic factor = poor B 12
  • poor bicarbonate response = too acid
Bile functions
  • helps alkaline chime
  • decrease fat surface tension
  • facilitates emulsifaction and absorption of fats
  • lubricate intestine
  • helps elimination
  • binds toxins
key liver functions
  • clean blood from digestion before heart (vena Cava)
  • neutralize toxins
  • nutrients metabolized to active form
  • traffic - what goes where
  • bile produced from cholesterol
  • amino acids build proteins
  • glycogen produced, stored, released
  • regulates blood levels - hormones, sugars, proteins, fats
  • metabolism of macronutrients
problem with not eliminating regularly
  • ground for bacteria
  • flora imbalance
  • recirculate toxins
  • estrogen dominance
  • headaches
  • fatigue
  • breast & colon cancer
  • haemorrhoids
Action Potential

AT Rest


  • more potassium (K)inside cell, more sodium (Na) outside cell
  • not allowed to move freely
  • maintains a negative charge

Stimulus


  • a neuron or sense opens the gate at one end of neuron
  • Na starts entering cell
  • cell starts having a positive charge
  • domino affect along cell
  • depolarization of cell membrane
  • THE positive charge is the message

ACTION potential arrives


  • vesicle travels to cell membrane and releases neurotransmitter
  • in the synapse attaches to a receptor

Key Neurotransmitters & function


  1. Epinephrine - stress responce
  2. norepinephrine -less intense
  3. acetylcholine - motor & memory
  4. dopamine - attention, concentration, control movement
  5. serotonin - satisfaction
Negative feedback loop
  • sense perception
  • afferent
  • interneuron
  • efferent
  • efferent organ
    (somatic or autonomic)

What is supposed to be readily permeable to blood-brain barrier

  • water
  • glucose
  • some amino acids (make neurotrans)
Neural/nervous nutrients
  • amino acids & EFA = brain building blocks
  • sodium = usually enough unless dehydrated
  • calcium & magnessium = conductivity
  • B Vitamins = myelin sheath, conductivity
Endocrine functions
  • co-ordinate and direct the body's cells
  • long-term process (vs instant of CNS)
  • growth and development
  • metabolism
  • reproduction
  • body defences
  • homeostasis
endocrine vs exocrine

end = in to the blood


exo = in to the body cavity

main steroid hormones / attach

  • cholesterol
  • sex hormone
  • adrenal hormones
  • binds to cells DNA

Main non-steroidal hormones /attach

  • amino acids
  • insulin
  • parathyroid
  • bind to receptors on membrane
Lipid metabolism
  • bile = emulsify
  • lipase = breakdown to monoglycerides, glycerol, fatty acids
  • Lymphatic lacteels absorb monoG and FA
  • blood absorbs glyverol, short-chain FA
liver decides to do 3 things with nutrients
  1. Use for self
  2. Store
  3. release to body

specific vs non-specific immunity

non = from birth, mother


specific = acquired, memory

3 levels of immune defence
  1. physical barrier
  2. destructive cells
  3. Immune system
physical barrier defence
  • anything that traps
  • mucus memberanes
  • skin
  • tears
  • earwax
  • HCl
  • sweat
  • saliva
2nd - detructive cell barrier
  • phagocytic macrophages
  • antimicrobrial
  • inflammatory cascas
  • natural killer cells
  • fever
3rd - immune
  • antigen specific
  • memory - later targeted response by lymphocytes (B and T cells) and nacrophages
lymphatic system
  • drains extra fluid
  • returns leaked plasma & proteins to blood
  • removes bacteria, wastes, toxins
  • defends and cleanses
  • sites of surveillance for immune system
  • defends & cleanses
cell theory

what happens at a cellular level correlates to what happens on macro level


cells need nutrients, oxygen, to eat and excrete

cell functions
  1. growth
  2. make proteins
  3. protection
  4. nutrient storage
  5. division
  6. create energy
  7. movement
  8. control/info gathering
  9. connect - structure, connective, bones
3 types of energy production
  1. Aerobic (1:32)
  2. Anaerobic (1:2)
  3. ADP Phosphorylation (1:1) / creatine
Muscle contraction
  • acetylcholine - chemical message from nerves
  • stimulus = action potential
  • calcium release is caused
  • contraction begins
  • sarcomere filaments walk towards each other
  • calcium recaptured = reduced
  • muscle/sarcomere release


i.e. rigamorteous - no ATP to recapture calcium so muscles do not release until calcium disapates

body tissue definition
cells that perform the same function
3 types of junctions
  1. adhesive = strong but fluid (protein connect)
  2. tight junction = barrier (selective permeable)
  3. gap junction = communication
    (heart, smooth muscles, nervous)
Tissue Repair
  1. Regeneration - replaced damage cells
  2. Fibrosis - dense connective tissue, scar

  • capillaries become perm
    - flush area with nutrients and oxygen
  • arterials constrict
    - stop blood loss
  • granulated tissue forms
    - cell layer repair under injury
  • surface epithelium regenerates
  • Fibrosis
    - fibrin, collagen, connective tissue give structure; less flexible and organized = scar
2 stages of protein synthesis

1. Transcription


2. Translation

Transcription basic steps
  • takes place inside nucleus
  • a section of DNA unwinds and unzips
    (packing for vacation vs. all your clothes)
  • mRNA reads one side of unzipped DNA
  • pairs match up (A+U / G+C)
  • DNA rezips
  • mRNA exits nucleis
Translation basic steps
  • mRNA goes to ribosomes
  • ribosomes read code
  • ribosomes bring tRNA with anti-codon
  • matches amino acid
Damages DNA
  • free radicals
  • pollution
  • heavy metals
  • radiation
Replication & Tumous
  • DNA prone to errors due to sheer volume
  • enzymes to catch and remove errors
  • exposure to damaging factors build up over time
  • nutrition - missing enzymes and cofactors
  • Tumours = no housekeeping, errors not being removed therefore duplicate and proliferate
DNA nitrogen bases + RNA variant

Purine


Adenine


Guanine


Pyrimidine


Cytosine


THymine


RNA


Uracil

Skin NUtrients
  • antioxidants A, C,E, Selenium, Zinc
  • B Vitamins
  • EFA
nail signs
  • white spots = copper or zinc deficit
  • vertical ridges = low HCL
  • horiz ridges = heavy metal
  • furrow = trauma during growth
Tissue ability to regenerate

Depends on type of tissue, severity, resources


  1. epithelial - easily if well nourished
  2. connective - if adequate blood supply or scar
  3. muscle - poor, cardiac mostly scar
  4. nerves - poor to none
Hormone production stimulated 3 ways
  1. hormonal - pituitary release TSH
  2. Humoral - fluids in body carry monitors
  3. Neurol - Sympathetic nervous stimulates adrenals
nutritional triad
  1. eat - building blocks
  2. digest - need to breakdown
  3. absorb - not absorb= not benefit
signs how well absorbing nutrients

good choices in journal but:


  • energy level
  • physical appearance "shiny coat"
  • inflammation
  • gas, bloating, gerd
  • allergies

why minerals like calcium & iron hard to absorb


why HCL helps

  • calcium/iron have positive charges
  • so does intestinal lining
  • like repel likes
  • stomach producing enough acid = minerals pick up extra positive charge
  • can then bind with protein
  • easily absorbed
unfolding protein
  1. food enters stomach
  2. raises HCL
  3. HCL unfolds protein
  4. activates pepsinogen to pepsin
  5. triggers more pepsinogen to be released
  6. food level reduces
  7. HCl and pepsinogen decrease
sign bad protein digest
  • smelly poop and gas
hard tummy?
  • stomach still reacting to irritation
  • we stop hearing feedback - "shock"
  • reaction stops but the irritation
  • lack of reaction but can be seen in allergies, acne, arthritis
HCL supplement or not

Will it stimulate or replace stomach function?
Will pepsinogen, mucus, intrinsic factor respond?


  • HCL supplements to get them kick started
  • transition to food stimulations
  • bitters, apple cider vinegar, fermented foods
  • even coffee - but not if gerd
how can pancreas become fatigued and depleted
  • poor food choices require extra work
  • lack of dietary food enzymes
  • poor digestion in mouth & stomach requires extra work by pancreas to pick up the slack

problem relying on pancreas
  • alkaline process versus acidic
  • slow - food slow leaving stomach
  • completion - less complete - malabsorption and immune responce
  • constipation - mouth/stomach/HCL stimulate peristalsis and elimination functions
too much fat interferes with
  • liver
  • red blood cell function
intestinal flora benefits
  • make b vitamins
  • make vitamin k
  • make lactic acid - digest, absorb, peristalsis
  • heal large intestine
  • hinder 'bad' bacteria
  • die-off bulks up stool
  • supports immune system
chronic inflammation cycle
  • irritant
  • inflammation
  • more blood to area
  • try to flush away irritant (WBC, nutrients)
  • if irritant produced faster than flushing
  • chronic inflammation
  • disease state - "it is" (eg colitis)
  • pores of intestine enarge
  • incomplete food passes through
  • triggers allergies
  • immune response




problem with just using anti-inflammatory drugs
  • inflammation part of immune responce
  • chronic = chronic irritant
  • drugs treat inflammation - not cause
  • so protective quality reduced, irritant persists = increased damage, illness
toxic gallbladder sign
  • overworked liver leaks toxins in to gallbladder and duedenomun
  • feel worse after eating
  • "hot spot" like ulcer but lower
  • migraines
  • chronic neck problems
  • knee problems
  • skin problems
cortisol and inflammation cycle
  • for chronic stress and inflammation
  • at first weight loss, then resource storage
  • reduces inflammation (not irritant)
  • needs stronger and stronger over time
  • suppresses immune responce
  • ultimately inflammation rises in order to be heard
blood stream and mucus
  • toxins in blood stream
  • membranes secrete mucus
  • if not drained quickly, congestion
  • reduces circulation
  • reduces nutrient delivery
  • prone to problems
  • expecially if waste removal slowed
lymph overload & T-Cells
  • loose control over T-Cell
  • Underactive = yeast, worms, fungus
  • Overactive = attack body itself - AI
    RA = WBC attack joints
  • dramatic reverses when lymphatic function regained
WBC nutrients
  • Vit A, C, zinc
  • Sugar paralyzes
disacharides
  • sucrose (glucose+fructose)
  • lactose (glucose+galactose)
  • maltose (glucose+glucose
  • need enzymes to break down for absorption

monosacharides
  • glucose
  • fructose
  • galactose
  • glucose absorbed immediately
  • fructose & galactose can be absorbed immediately or stored as glycogen
polysacharide
  • starch
  • complex carbohydrates
  • need enzymes = glucose

3 or more signs of metabolic syndrome

  1. High fasting blood glucose (+5.6)
  2. High blood pressure (130/85)
  3. High triglycerides (+1.7)
  4. Low HCL (-1.0)
  5. Abdominal obesity (102cm/135)

Insulin resistance affects

  • weight gain (insulin builds fat for glucose)
  • higher blood pressure
  • cardio vascular disease
  • higher cholesterol & triglycerides
  • = more rrsistance

Reactive hypoglycemia

  • hangry
  • over react to big carb challenge
  • big carb load = big insulin response
  • too fast drop in blood glucose level
  • liver/adrenal compensation

Metabolic syndrome recs

  • 30 min exercise
  • diet - GI index counts, less simple sugars
  • chromium - enhances insulin binding
  • enough fibr
  • magnesium + correct deficiency improves glucose tolerance
  • b vitamins
  • green tea

Enzyme needed for omega 6 or 3 conversion

Delta-6-desaturase (D6D)

D6D co-factors

Magnessium and zinc

Kidney functions

  • heart beat
  • blood pressure
  • fluid balance
  • Better to raise potassium than reduce sodium

Term for red blood cell formation

Hematopoiesis

Where RBC formation take place

  • red marrow
  • flat bones
  • skull, pelvis, ribs, sternum,
  • proximal epiphanies humerus, femur