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79 Cards in this Set

  • Front
  • Back

T/F


Transduction is the conversion of energy into electrical impulses in specialized nerveendings in response to pain that exceeds the nociceptor’s threshold.

True

One common physiologic response to pain is

an increased heart rate and blood pressure level

The analgesic effect of opioids is due to their:

interaction with specific opioid receptors in the brain and spinal cord.

The analgesic effect of NSAIDs is due to:

modification of the inflammatory response

The term antipyretic is used to describe a drug that relieves:

Fever

_______ refers to an increased response to a stimulus that is normally painful so that less andless stimulation is required to produce pain, whereas _______ refers to the production of painin response to a stimulus that does not normally provoke pain.

Hyperalgesia; allodynia

Pain is considered to play such an important role in overall health and well-being that it isnow considered a fifth:

Vital Sign

Kappa and Mu are

types of opioid receptors in the central nervous system

Multimodal analgesia takes advantage of the _________ obtained by combining two or moreclasses of analgesic drugs to alter more than one phase.

synergistic effects“doubled”

The presence of both hyperalgesia and allodynia collectively is called:

the wind-up phenomenon

Elective soft tissue procedures for dogs, such as spaying or castration, usually require howmany days of postoperative treatment with NSAIDs?

3 - 4 days

Which of the following is a normal finding when using a 2 -agonists?

Bradycardia

Which is the correct order of the phases of nociception?

Transduction, transmission, modulation

Lidocaine and bupivacaine are examples of which drug class?

Local anesthetics

Describes the transduction phase of nociception

The conversion of energy into an electrical impulse

Aversive sensory and emotional experience that elicits protective motor actions, results inlearned avoidance, and may modify species-specific behavior traits, including socialbehavior, is best known as:

Pain

Known as “ouch” pain, which of the following protective sensations of pain occurs when thereis a possibility of or actual tissue injury?

Physiologic

Chemical mediators, such as prostaglandin and histamine, are responsible for:

Inflammatory pain

Pain originating from the musculoskeletal system is best described as:

Somatic pain

A common class of drugs utilized to treat and target specific receptors in the pain pathwayincludes:

NSAIDs



what is not typically associated with neuroendocrine changes that occur inresponse to pain?

Increased insulin release

The use of preemptive analgesia is likely to:

Prevent "wind up"

Patients that are suffering from pain are likely to experience noticeable alterations in their:

facial expressions, appearance, and attitude

Perioperative analgesia is the concurrent use of:

preemptive analgesia and multimodal therapy

Opioid agonist drugs act in which of the following ways?

Centrally: to inhibit perception in the brain and sensitization in the spinal cord

Caution should be taken with rapid intravenous injection of morphine in canine patients dueto the potential for:

histamine release

This paradoxical response in canine patients after the administration of oxymorphone canmake which of the following procedures difficult?

Thoracic radiographs

Of the synthetic opioids, which is known to also act as an antagonist at the NMDA receptor?

Methadone

In contrast to other pure opioid agonists, the duration of action achieved with intravenousfentanyl administration is:

20 - 30 mins

Due to the pH of the feline mucosa, which injectable narcotic can be administered orally foranalgesia?

Buprenorphine

General duration of action for buprenorphine following intramuscular injection is thought tobe:

6 - 12 hours

Butorphanol can be used as an antagonist to partially reverse respiratorydepression/sedation secondary to the use of:

Mu agonist opioids

The use of morphine administered through an epidural route is most likely to illicit whichadverse effect?

Urine retention

Which opioid should not be administered concurrently with the use of transdermal fentanyldue to risk of partial blockage of opioid receptors and reduced analgesic effect?

Buprenorphine

The NSAID that acts as a potent analgesic for both somatic and visceral pain is:

Carprofen

Clinical effects of NSAIDs are due to their inhibition of what chemical synthesis within thebody?

Prostaglandin

COX-2 isoenzyme is

Inducible


Found in the CNS, kidneys, and eyes


Linked to analgesic effects




In is NOT present in most tissues

The use of NSAIDs that results in renal toxicity is most likely due to the blockage of

PGE 2

Opioids are effective in the nociceptive pathway in all areas except:

Transmission

Local anesthetics are effective in the nociceptive pathway in all areas except:

Perception

Absence of pain sensation is best known as:

Analgesia

The concurrent use of NSAIDs and corticosteroids is contradicted due to which adverse sideeffect?

Gastric ulceration

Perception of pain takes place in the:

Cerebral cortex

Transmission of pain takes place in the

Sensory Nerves

Modulation of pain takes place in the

Spinal cord

What is involved in spaying a dog

Removal of: ovaries, uterine body, uterine horns

T/F


It is possible that animal pain is experienced as worse than human pain in the samesituation.

T



NIOSH

National Institute for Occupational Safety and Health

RELs

Recommended Exposure Limits

OSHA

Occupational Safety and Health Administration

Short term effects of breathing in WAG

fatigue, headache, drowsiness, nausea, depression

Long term effects of breathing WAG

Reproductive disorders, liver and kidney damage, bone marrow abnormalities, chronic nervous system dysfunction



Components of Scavenging System

Waste gas port


Transfer tubing


Interface


Gas evacuation system

Alternative scavenging system

activated charcoal canister

T/F


WAGs are a potential hazard to personal, but problems that arise are only of long term nature

FALSE

T/F


Long term toxicity of inhalation anesthetics is thought to be caused by the release of toxic metabolites during the breakdown of these drugs within the body

TRUE



The volatile inhalant general anesthetic thought to be least toxic, because very little is retained and metabolized, is:

ISOFLURANE

WAG for iso and sevo should not exceed:

2

How often should a test for low pressure leaks be conducted?

Each day the machine is used

The safest way to transport large compressed gas cylinders is:

using a hand cart



The minimum # of air changes per hour that should be available in a room in which WAG is present

15



A technician may reduce the amount of waste gases by:

Using cuffed edotracheal tube




Ensuring that anesthetic machine has been tested for leaks




Using an injectable agent rather than mask chamber

To conduct a low pressure test on an anesthetic machine (with a rebreathing circuit) you must

Close the pop off valve and occlude the patient end of the breathing circuit




Compress the reservoir bag




Pressurize the circuit with a volume of gas

Pathologic pain

Prolonged and exaggerated

Visceral Pain

Originates from organs

Allodynia

Phenomenon in which an area close to the site of tissue injury is painful if stimulated with a normally non-noxious stimulus

Simple descriptive scale

allows assessor to rate degree of pain

Visual analogue

scale consists of a "ruler"


left line no pain


right line worst pain

Numeric rating scale

pain assigned to one of several levels



Categorical numeric rating scale

series of numeric rating scales with descriptions

Opioids provide analgesia by:

action on opioid receptors in both the spinal cord and brain as well as some peripheral tissues

The process by which thermal, mechanical, or chemical noxious stimuli are converted into electrical signals called action potentials is

Transduction

In the spinal cord, pain impulses can be altered by neurons that either suppress or amplify nerve impulses. This is known as

Modulation

Where in the pain pathway does secondary sensitization or wind up occur?

Spinal cord



T/F


The dose of each drug is decreased when several drugs are used

True

What is NOT a potential side effect of opioid administration?

Renal failure

What is the Mechanism of Action of NSAIDs

Inhibit prostaglandin synthesis

T/F


Treating pain does NOT improve wound healing

FALSE

Drug groups that are most often given CRI

Local anesthetics,


Opioids


NMDA