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EXAM 3 ANATOMY LECTURE 33: ENDOCRINE
EXAM 3 ANATOMY LECTURE 33: ENDOCRINE
Char of endocrine glands
1. encapsulated in CT
2. secretory cells
3. richly vascularized
4. secrete into extracellular space
Pituitary gland (hypophysis)
Infundibulum stalk hangs from hypothalamus.

Between the optic chiasm and mammillary bodies.

Sits in sella turcica

Surrounded by Circle of Willis and cavernous sinus.
How is the pituitary gland held in place?
By the diaphragma sellae
What are the parts of the adenohypophysis (ant. pituitary)?
1. pars tuberalis
2. pars intermedia
3. pars distalis (anterior lobe)
Parts of neurophypophysis?
1. median eminence
2. infundibular stalk
3. pars nervosa (posterior lobe)
ADH
1. milk EJECTION
2. uterine contraction
Thyroid gland
LARGEST pure endocrine gland.

Two hormones:
1. thyroid hormone
2. calcitonin
What are the two types of cells of thyroid gland?
1. follicular cells
2. parafollicular cells
Follicular cells
1. cuboidal to low columnar
2. make thyroglobulin
3. thyroglobulin is converted to thyroid hormone via TSH stimulation.
Parafollicular cells
1. C (clear) cells
2. produce calcitonin: regulates Ca blood level by reducing it.
Parathyroid hormone
1. Raises Ca blood level
2. increases activity of osteoCLAST (resorption of Ca from bone).
3. increases Ca reabsorption in kidneys
4. promotes production of Vit D
What are the two cell types of parathyroid hormone?
1. Principle chief cells (produce PTH)

2. Oxyphil cells (unknown function).
Adrenal cortex
1. zona glomerulosa (aldosterone production)
2. zona fasiculata (cortiso production)
What are the distinctive features of steroid secreting cells?
1. abundant sER
2. no secretory granules
3. mito have unusual cristae
4. lipids abudant in cytoplasm
Cells (hormones) produced by pancreatic islets?
1. alpha (glucagon)
2. beta (insulin)