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18 Cards in this Set
- Front
- Back
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What is the difference between the organization of PNS vs CNS?
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CNS- brain and spinal cord
PNS- neurons intervates particular target tissues |
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What are the key words used to describe the Parasympathetic vs Sympathetic Nervous System?
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Sympathetic- fight or flight
Parasympathetic- digestion and vegetation |
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Draw and identity PNS neuroanatomy? (pre and post synaptic membranes/neurons/receptors)
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See notes
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Draw and identity SNS neuroanatomy (pre and post synaptic membranes/receptors/NT/neurons).
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See notes
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The therapeutic index for many medications will generally increase in elderly patients.
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strongly disagree because would tissue in elderly thus more sensitive to drugs and decreasing therapeutic index;
LD 50/ED 50 ratio of therapuetic index |
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What determines addiction behavior (drug dependence)?
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3 or more additive symptoms; e.g. tolerance, quitting/restarting, abandonment of life duties
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Describe difference between 3 drug-drug interactions.
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Synergistic-potentiating effects
Additive- when given together, they equal out effects Antag- block each other |
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Where are adrenergic receptors on target tissues for the SNS are located on the:
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post synaptic membrane of post synaptic neuron
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What drugs are safe during pregnancy?
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acetaminophen, penicillin, cephalosporins, erythromycin, nitrofurantoin, H2 blockers, antacids, heparin, hydralazine, methyldopa, labetolol, insulin, docusate, Metronidazole
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What breaksdown and metabolize catecholamines?
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MAO are keys to metabolism of catecholamines
COMT breakdown NE, dopamine and Epi |
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What is the difference between sec. vescile reuptake protein vs. axon terminal reuptake protein?
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axon terminal- controls removal of NE from synapse
sec. vesicle- controls removal of NE from cytoplasm |
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Cocaine, an axon-terminal reuptake protein inhibitor, could cause an exaggerated SNS state in person who injects this drug. Why?
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Fight or flight will increase and get into extremely agitated state if cocaine on board
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What will happen if hypertensive patient given alpha 2 adrenergic agonist?
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if given will inhibit release of NE and decrease blood pressure and stop fight/flight response.
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Relaxation of smooth muscle that lines GI tract is mediated by muscarinic cholinergic receptors during F/F situation?
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Strongly disagree, for multiple reasons but main is that muscarinic increases peristalsis in PNS response only. F/F is SNS response which does not include muscarinic receptors
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Relaxation of smooth muscle that lines GI tract is mediated by muscarinic cholinergic receptors during F/F situation?
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Strongly disagree, for multiple reasons but main is that muscarinic increases peristalsis in PNS response only. F/F is SNS response which does not include muscarinic receptors
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Since alpha 1 mediates active F/F responses, this is the sub-type of receptor that Ach binds to in order to stimulate peristalsis during digestion.
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Strongly disagree; muscarinic is not adrenergic receptor so focus on that. Only active and passive when discussing SNS
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What are building blocks of SNS?
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phenylalanine, tyrosine, dopa, dopamine, norepinephrine, epinephrine
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baclofen is an effective treatment of muscle paralysis caused by myesthenia gravis?
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Strongly disagree because used to stop spastic activity and destrony nicotinc receptor to prevent spasms
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