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79 Cards in this Set

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Gross Anatomy Of Long Bone


Periosteum

Outer fibrous layer

Outside

Gross Anatomy of Long Bone


Diaphysis

Shaft

Gross Anatomy of Long Bone


Epiphysis

Expanded ends of bone


Spongy bone interior


Epiphyseal line (remnant of growth plate)


Articular (hyaline) cartilage on joint surfaces

Microscopic Anatomy


Compact Bone

Osteon (Haversian System)- structural unit


-Lamellae: weight bearing, column like matrix cubes


-Central (Haversian) Canal: contains blood vessels and nerves


-Perforating (Volksmann's) Canals: at right angles to the central canal. Connects blood vessels and nerves of periosteum and central canal


-Lacunae- small cavities that contain osteocytes


-Canaliculi- hairlike canals that connect lacunae to each other and the central canal.

Microscopic Anatomy


Spongy Bone

-Trabeculae- aline along lines of stress. No osteons, contain irregularly lamellae, osteocytes, and canaliculi.


*capillaries in endosteum supply nutrients

Homeostatic Imbalances


Osteoporosis

-Loss of bone mass: bone resorption outpaces deposit


*spongy bone of spine and neck of femur become most susceptible to fracture.

Integumentary Functions


Excretion

Salt and Nitrogenous wastes in sweat.

Integumentary Functions


Blood Reservoir

Up to 5% of body's blood volume.

Region


Dermis

Middle region

Integumentary Functions


Cutaneous Sensations

-Pain


-Pressure


-Temperature

Burns


(Causes, results, threats)

-Causes- heat, electricity, radiation, certain chemicals


-Results- Tissue damage, denatured protein, cell death


-Threat- dehydration and electrolyte imbalance, leading to renal shutdown and circulatory shock.

Fibrous Joints


Gomphosis

-"Peg in socket" fibrous joint


- Periodontal ligament holds tooth in socket


-Immovable

Fonatelles

-"Soft spots" of infants skill (fibrous membranes between cranial bones)


-"Molding" allows easier passage through birth canal


-Closed by the end of 2nd year

Factors Influencing Bone


Growth


Physical stress

Stimulates bone growth

Factors Influencing Bone


Growth


Bone Deposit

Requires vitamin A, C, D, and several minerals

Factors Influencing Bone Growth


Sex Hormones

A. Promote bone formation


B. Stimulate ossification of epiphyseal plates

Factors Influencing Bone Growth


Deficiency of Thyroid Hormone

Delays growth

Factors Influencing Bone Growth


Low HGH & High HGH

Low- dwarfism


High- gigantism

Factors Influencing Bone Growth


Growth Hormone

Stimulates epiphyseal plate activity

Cells Of Bones


Osteoclasts

Cells that break down (resorb) bone matrix

Cells Of Bone


Osteocytes

Mature bone cells

Cells Of Bones


Osteoblasts

Bone forming cells

Cells Of Bones


Osteogenic (osteoprogenitor) cells

Stem cells in periosteum and endosteum that rise to osteoblasts

Region


Epidermis

Superficial region

Region


Hypodermis

Deepest region

Integumentary Functions


Metabolic Functions

Synthesis of vitamin D

Burns


Third Degree

-Entire thickness of skin damaged


-Gray-white, cherry red, or black


-No swelling or pain


-Skin grafting usually necessary

Burns


Second Degree

-Epidermal and upper dermal damage


-Blisters appear

Burns


First Degree

-Epidermal damage only


-Localized redness, edema, and pain

Skin Color


Carotene

Yellow to orange, most obvious in the palms and soles

Skin Color


Melanin

-Yellow to reddish-brown to black, responsible for dark skin colors

Skin Cancer


Basal Cell Carcinoma

-Least malignant, most common


-Stratum basale cells proliferate and slowly invade dermis and hypodermis


-Cured by surgical excision in 99% of cases

Skin Cancer


Melanoma

-Most dangerous


-Characteristics (ABCDE rule)


A. Asymmetry


B. Border


C. Color


D. Diameter


E. Evolving


-Involves melanocytes


-Highly metastatic and resistant to chemotherapy


-Treated by wide surgical excision accompanied by immunotherapy

Skin Cancer


Squamous Cell Carcinoma

- second most common


- involves keratinocytes of stratum spinosum


-most common on scalp, ears, lower lip, and hands


- good prognosis if treated by radiation

Integumentary Functions


Protection

- Chemical Barriers: skin secretions fight bacteria. Melanin protects against uv rays


- Physical/Mechanical Barriers: keratin and glycolipids block most water/water soluble substances


- Limited penetration of skin by lipid-soluble substances


- Biological Barriers: dendritic cells and macrophages

Integumentary Functions


Body Temperature Regulation

Sweat for evaporative cooling



Constriction of dermal capillaries to prevent heat loss

Synovial Joint Movement


Angular Movements


(Frontal Plane)

- movements that occur along the frontal plane


1. Abduction- movement away from midline


2. Adduction- movement toward the midline


3. Circumduction- felxion + abduction + extension + adduction of a limb

Fibrous Joint


Syndesmosis

- joint held together by a ligament


- vary in length; longer than sutures


- on end of tibia


-immovable

Fibrous Joint


Syndesmosis

- joint held together by a ligament


- vary in length; longer than sutures


- on end of tibia


-immovable

Fibrous Joints


Suture

- Joint held together with very short, interconnecting fibers, and bone edges interlock


* Found only in skull


- Immovable

Cartilaginous Joints


Synchrondroses

- bones united by hyaline cartilage


*epiphyseal plate


*sternum


*joint between first rib and sternum


*immovable

Cartilaginous Joints


Symphyses

- bones united by fibrocartilage


*spine disc


*pubic symphysic


*moveable

Synovial Joint Movements


Angular movements (Sagittal plane)

- movements that occur along the sagittal plane


1. Flexion- decreases angle of joint


2. Extension- increases angle of joint


3. Hyperextension- excessive extension beyond normal range of motion

Synovial Joint Movement


Gliding

One bone surface glides or slips over another similar surface.

Synovial Joint Movements


Rotation

- the turning of a bone around its own long axis


- between c1 and c2 vertebrae


- rotation of humerus and femur


-rotation of the head, neck, and lower limb

Synovial Joint Movements


Special Movements (radius around ulna)

- movements of radius around ulna


- radius and ulna are parallel


•Supination: turning hand backward


•Pronation: turning hand forward (radius rotates over ulna)

Synovial Joint Movements


Special Movements (movement of the foot)

• dorisflexion: upward movement


• plantar flexion: downward movement


• inversion: turn sole medially


• eversion: turn sole laterally

Synovial Joint Movements


Special Movements (transverse plane)

• protraction: anterior movement


• retraction: posterior movement



• elevation: lifting a body part superiorly


• depression: moving a body part inferiorly

Classification Of Synovial Joints


Pivot joints

- rounded end of one bone conforms to a "sleeve" or ring of another bone


- uniaxial movement only


-(proximal radioulnar joint)

Classification Of Synovial Joints


Condyloid (ellipsoidal) Joints

- biaxial joints


- both articular surfaces are oval


- permit all angular movements


-metacarpophalangal joint

Joints


- Articulation


- Functions

- Articulation: site where two bones meet


- Functions: give skeleton mobility and holds skeleton together

Skin Color


Hemoglobin

Responsible for the pinkish hue of skin

Synovial Joints (distinguishing features)


6. Rich nerve and blood vessel supply

- nerve fibers detect pain, monitor joint position and stretch


- capillary beds produce filtrate for synovial fluid

Synovial Joints (distinguishing features)


5. Three possible types of reinforcing ligaments

- Capsular (intrinsic): part of the fibrous capsule


- Extracspsular: outside the capsule


- Intracapsular: deep to capsule; covered by synovial membrane

Synovial Joints (distinguishing features)


4. Synovial Fluid

- viscous slippery filtrate of plasma + hyaluronic acid


- lubricates and nourishes articular cartilage

Synovial Joints (distinguishing features)


3. Articular (joint) Capsule

- outer fibrous capsule


-inner synovial membrane

Synovial Joints (friction-reducing structures)


Bursae

Flattened, fibrous sacs lined with synovial membranes

Synovial Joints (friction-reducing structures)


Tendon sheath

Elongated bursa that wraps completely around a tendon

Synovial Joints (distinguishing features)


2. Joint (synovial) Cavity

Small potential space

Synovial Joints (distinguishing features)


1. Articular Cartilage

Hyaline cartilage

Synovial Joints

All are diarthrotic (freely moveable)



Include all limb joints; most joints of the body

Major Synovial Joints


Shoulder

1. Ball-and-socket: head of humerus, glenoid cavity of scapula


2. Loose cavity, reinforced by surrounding muscles and tendons (rotator cuff)


3. Several bursae


4. Variety of movements, but easily dislocated

Major Synovial Joints


Elbow

1. 2 types of joints


A. Hinge Joint: trochlea of humerus and trochlear notch of ulna


B. Plane Joint: captiulum of humerus and head of radius (rotation of radius wishing annular ligament


2. Joint capsule is reinforced by collateral ligaments

Major Synovial Joints


Hip

1. Ball-and-socket: head of femur and acetabulum of coxal bone


2. Fibrocartilage ring deepens acetabulum cavity


3. Heavy joint capsule reinforced by ligaments


4. Variety of movements

Major Synovial Joints


Knee

1. 2 condyloid joints: between femur and tibia


-Flexion and Extension


- Some rotation of lower leg when knee is flexed


2. Plane joint: between femur and patella


3. Several ligaments bind articular surfaces


4. Femur and tibia separated by 2 menisci


5. Several bursae

Classification of synovial joints


Ball and socket joints

-multiaxial joints


-most freely moving synovial joints


*shoulder joints

Classification of synovial joints


Saddle joints

- biaxial


- allow greater freedom of movement than condyloid joints


- each articular surface has both concave and convex areas


- (carpometacarpal joint of thumb)

Classification of synovial joints


Hinge joints

- uniaxial joints


- motion along a single plane


- flexion and extension only


- (elbow joint)

Synovial joint moments


Special movements


(Opposition of the thumb)

Movement in the saddle joint so that the thumb touches the tips of the other fingers

Classification of synovial joints


Plane joints

- nonaxial joints


- flat articular surfaces


- short gliding movement


- (intercarpal joint)

Cells of epidermis


Dendritic cells

- star shaped dendrite cells arise from bone marrow and migrate to the epidermis


- "langerhans" cells

Cells of epidermis


Melanocytes

- spider shaped epithelial cells that synthesize the pigment melanin are found in the deepest layer of the epidermis

Cells of epidermis


Keratinocytes

- produce keratin, the fibrous protein that helps give the epidermis its protective properties


- arise from deepest part of the epidermis from cell layer called stratum basale


- tightly connected by desmosomes

Cells of epidermis


Tactile cells

- present at the epidermal- dermal junction


- shaped like a spiky hemisphere, each tactile cell is intimately associated with a disc like sensory nerve ending

Layers of epidermis


Stratum basale (basal layer)

- deepest epidermal layer, is attached to the underlying dermis along a wavy borderline that reminds one of corrugated cardboard

Layers of epidermis


Stratum granulosum (granular later)

- consists of 4 to 6 cell layers in which keratinocyte appearance changes drastically and the process of keratinization begins

Layers of epidermis


Stratum spinosum


( prickly layer)

- several cell layers thick


- these cells contain a weblike system of intermediate filaments, mainly tension-resisting bundles of pre-keratin filaments, which span their cytosol to attach to desmosomes.

Layer of epidermis


Stratum cucidum


(Clear layer)

- through the light microscope, is visible only in thick skin, is a thin translucent band just above the stratum granulosum


- consists of 2 or 3 rows of clear, flat, dead keratinocytes within distinct boundaries

Layers of epidermis


Stratum corneum


(Horny layer)

- an abrupt transition occurs between the nucleated cells of the stratum granulosum and the flattened anucleate cells of the stratum corneum


- outermost epidermal layer is a broad zone to 20 to 30 cell layers thick that accounts for up to three-quarters of the epidermal thickness