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8 Cards in this Set
- Front
- Back
- 3rd side (hint)
The chronic inflammatory process is marked by presence of what type of cells?
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Mononuclear cells (particularly macrophages)
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NOT PMN
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If the connective tissue scaffolding is partly or totally destroyed, then tissue repair will ultimately result in _____________?
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Scarring
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The 2 mechanisms for wound healing and repair are _______________
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1. Regeneration of parenchymal cells. 2. replacement by connective tissue.
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cells that can regenerate vs not
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In wound healing, replacement by connective tissue is characterized by what 3 things?
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sequential development of granulation tissue, fibrosis, and eventually fibrous scar formation
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What are labile cells?
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Cell that proliferate normally (ex: bone marrow, epithelia, lymphocytes...)
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What are stable cells?
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Cells that do not proliferate normally but can if injured. (ex: fibroblasts, osteoblasts, smooth musc, hepatocytes...)
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What are permanent cells?
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No longer replic b/c highly specialized and differentiated (neurons, cardiac muscle, etc)
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What is EGF? Where does it bind? [Tissue Repair Mediators]
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Epidermal growth factor, mitogenic to epithelial cells, fibroblasts, hepatocytes. Binds c-erb1
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