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17 Cards in this Set

  • Front
  • Back
Hypertrophy:

Increase in cell ... resulting in an increase in organ size

DOES NOT imply an increase in the ... of cells

Can be physiologic or pathologic

Occurs in ... cells (e.g. cardiac myocytes)
-their only response to stress is to enlarge
-Often seen in patients with ...
size
number
nondividing
hypertension
look at slide 10 in lecture 15
ok
Hyperplasia:

Increase in the ... of cells in an organ or tissue typically resulting in an increased size of the organ or tissue

May occur together with hypertrophy

Can be physiologic or pathologic

Occurs in cellular populations which are capable of ...
number
mitosis
Left-sided heart failure:

... heart disease
Hypertension
... and ... valve disease
Myocardial disease
Ischemic
Aortic and mitral
Pure right sided heart failure most often occurs with chronic pulmonary hypertension and is called ...
-consequence of left-sided failure
cor pulmonale
What is the most common cause of myocarditis in the USA?
viruses
Myocarditis:

Infectious Etiologic Agents
-Viruses (most common cause in USA)
*... A & B and other enteroviruses (most common agents)
*Cytomegalovirus
*HIV
*Other
Coxsackieviruses
Myocarditis:
Infectious Etiologic Agents

Parasites
-... disease (Trypanosoma cruzi)
*Endemic in Central and South America
*Vector – Reduviid bug
-...
*Immunosuppressed
*HIV patients
-...
*Consumption of raw or undercooked meat (pork)
Chagas’
Toxoplasmosis
Trichinosis
look at slide 33 in lecture 15
ok
look at slide 42 in lecture 15
ok
Which primary cardiac tumor is most common in adults and in general?
myxoma
which primary cardiac tumor is most common in children and infants?
rhabdomyoma
What is the most common primary malignant cardiac tumor?
angiosarcoma
Cardiac Myxoma:

Benign neoplasm
Epidemiology
-Most common ... heart tumor in adults
-90% are in ...
-left:right ratio = 4:1
-... in atrial septum is favored site
-Sporadic and familial cases
*Majority are ...
primary
atria
fossa ovalis
sporadic
...:

Most common primary cardiac tumor in infants and children

May be sporadic or associated with ...

Some authors believe these are ... rather than neoplasms

Typically on right or left side of heart protruding into ... chamber

Associated with the potential for flow abnormalities if they grow to sufficient size to restrict the ventricular outflow tract

May result in heart ... and/or heart failure
Rhabdomyoma
tuberous sclerosis
hamartomas
ventricular
murmur
...:

Most common primary malignant tumor of the heart

Most frequent site is the ... but any chamber can be the site of origin

Plain radiography may show cardiac enlargement and/or abnormal cardiac contour

Echocardiography and CT may demonstrate mass

... best for demonstrating tumor extent
angiosarcoma
right atrium
MRI
Angiosarcoma:

Gross: bulky infiltrating mass with variable ...-... coloration and areas of ... and necrosis

Histology: usually poorly differentiated; anastomosing vascular channels forming ... sinusoids lined by atypical cells; patterns include spindle cell, angiomatous, undifferentiated/solid; prominent mitotic activity; hemorrhage and ... common
pink-red
hemorrhage
dilated
necrosis