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48 Cards in this Set

  • Front
  • Back

What are the 2 largest killers of children under the age of five?

Diarrhea and Pneumonia

Disease Example of sanitation/transportation

Yersinia Pestis (Bubonic Plague)

Deforestation causes Zoonosis - example

HIV

Natural disaster disease example

Cholera

Society and Behavior factors that lead to disease

- antibiotic resistance


- spread of STDs


- vaccination


- food production/distribution

Reservoir

- non-living or living source of pathogen

Virulence

the severity or harmfulness of a disease

Cell Theory

- Robert Hooke


- cell basic unit of life


- all organisms are composed of a fundamental unit - the cell


- all organisms are unicellular or multicellular


- all cells are fundamentally alike regarding their structure and metabolism


- life begets life

Who helped disprove spontaneous generation?

Louis Pasteur

3 Domains of Life

1 - Bacteria (Eubacteria)


2 - Archaea


3 - Eukaryotes (Eukarya)


All arised from single common ancestor 1st bacteria then archaea then eucarya

Phylogenetic Tree - what came first?

Prokaryotes 3.5 bya - stromatolites add oxygen to atmosphere 2.5 bya


- most


- eukaryotes and archaea most closely related

Prions

Ex: Mad cow, scrapie


- Acellular


- infectious protein particles


- no genome (no DNA or RNA)


- submicroscopic


- interact with a normal protein converting it to the infectious form

Viruses

Ex: HIV, measles, rabies


- Acellular


- Genome RNA or DNA inside protein capsid


- Obligate intracellular parasite (needs living cell to replicate)


- submicroscopic

Protozoans

Ex: malaria, leishmaniasis


- unicellular eukaryote


- DNA genome, asexual or sexual replication


- no cell wall


- some motile by flagella, cilia or pseudopods


- metabolism, heterotrophs


- important human pathogens, most are harmless

Algae

Ex: Dinoflagellates, diatoms, seaweeds


- unicellular or multicellular


- eukaryotic


- microscopic (unicellular) or macroscopic (multicellular)


- DNA genome


- cell wall usually cellulose


- metabolism - photoautotrophs


- not infectious - some dinoflagellates neurotoxin harmful to marine life or humans who eat toxin

Fungi

- unicellular (yeast); multicellular (molds, mushrooms)


- eukaryotic


- cell wall with chitin


- heterotrophs


- usually harmless or even beneficial - plant pathogens, few are pathogenic to humans

Prokaryotes

- bacteria and archaea


- 1-10 um


- DNA - rich region = Nucleoid


- no membrane bound nucleus

Eukaryotes

-10-100 um


- endosymbiosis


- protozoans, algae, fungi

5 ways to identify if alive

1 - made of prokaryote or eukaryote


2 - metabolism


3 - grow/develop


4 - reproduction - binary fission or sexual meiosis


5 - irritability - respond to stimuli

Smooth ER

- makes lipids

Golgi Apparatus

packaging and transport

Mitochondrion

cell respiration, ATP energy

Chloroplast

photosynthesis - makes carbs in plants

Lysosome

Digestion, recycle

Peroxisome

contains oxidative enzymes, detoxify

Central Vacuole

storage, water balance in plants

Cytoskeleton

maintain shape of cell


anchors organelles


made of microtubules and microfilaments

Fungi is a eukaryote with a

cell wall

Unique Archaea characteristics

- unicellular prokaryotes


- semi-rigid cell wall no peptidoglycan


- mono bilayer (biphytanyl) - Plasma membrane in some


- Methanogenesis


- no pathogens

Thermophiles

Withstand high heat using special enzymes and due to biphytanyl - least likely to be ripped apart

Methanogens

Use CO2 and H2 as a reducing agent to create methane(CH4) and H2O

Halophiles

- found in salt ponds and salt mines


- NaCl is harmful, pump themselves full of K+ ions to equalize ion balance


- hypertonic to isotonic environment

Endosymbiosis hypothesis explains...

why cetain cells have their own DNA, 70S ribosomes and divide by binary fission


- Mitochondria/Chloroplasts

Which domains reproduce Asexually?

Archaea and Bacteria

Algae cells are similar to _____ cells while protozoan cells are similar to _______ cells

Plant cells - Animal cells

Bacteria

Ex: E-coli


- Unicellular Prokaryotes


- DNA genome - replicate by binary fission


- cell wall (except mycoplasmas) made of peptidoglycan


- some motile by flagella


- metabolism:heterotrophs/autotrophs

Mesophiles

20-45 degrees C


- most pathogens

Psychrophiles

-5 to 15 degrees C

thermophiles

45-85 degrees C

Hyperthermophiles

85-200 degrees C

Obligate Aerobe

require oxygen

Facultative Anaerobe

prefer O2 but can survive without


(has both enzymes)

Obligate Anaerobe

lacks enzymes - makes O2 toxic

Neutrophiles

pH 5.5 to 8


- pathogens in humans mostly neutrophiles

Acidophile

pH 0 to 5


- helicobacter pylori - bacteria causes ulcers


- lactobacillus - in vaginal area - protect

Alkaliphiles

pH 8 to 12


- Vibrio cholera - lives in salt water

chemoautotrophs

- get energy from inorganic compounds (chemicals)

photoautotrophs

get energy from light


- cyanobacteria