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31 Cards in this Set

  • Front
  • Back

Neutrophil

Phagocytosis


Seen in infection and inflammation


Most abundant WBC in mammals

Heterophils

Similar to neutrophils but found in birds, reptiles, and some fish

Eosinophils

Capable of phagocytosis


Function is modulation of immune system


Seen in allergies and parasitic infections or infestations

Basophils

More numerous in horse and cattle


Function is mediation of immune system


Indicate inflammation or infectious conditions

Lymphocytes

Most abundant WBC in ruminants


Production of antibodies


Indicate viral infections

Monocytes

Phagocytosis


Indicate chronic infection

Pelger-Huet anomaly

Congenital defect


Have problems with bones and die young

Hypersegmentation

Can be due to aging either in vivo or in vitro


Prolonged storage


Patients on steroids

Dohle Bodies

Often seen with toxic granulation


Remnants of rough endoplasmic reticulum

Toxic granulation

Bacterial infection, inflammation, drug toxicity

Reactive Lymphocytes

Usually caused by antigenic stimulation

Smudge cells

AKA basket cells


caused by disease or error

Rouleaux

Stacking


Artifact of prolonged storage


Increased TS may be seen

Autoagglutination

Clumping


Occurs in immune mediated hemolytic anemia

Macrocytes

Problems with synthesis of blood cells


folic acid deficiency

Microcytes

Iron deficiency

Polychromasia

Young cells

Hypochromasia

Insufficient hemoglobin


Iron deficiency

Hyperchromasia

Greater than normal mean corpuscular hemoglobin concentration

Target cells

Iron deficiency anemia


Various forms of liver disease


Hypothyroidism


Blowing on wet smear

Ghost cells

Rupture of cell membrane - hemoglobin has leaked out


Immune mediated hemolytic anemia

Poikilocytes

Abnormally shaped RBC's

Schistocytes

RBC fragments


Trauma due to intravascular shearing

Acanthocytes

Hemangiosarcoma = dog


hepatic lipidosis = cat

Echinocytes

Artifact of slow drying


Renal failure, lymphosarcoma, snake bite

Keratocytes

Hemangiosarcoma, neoplasia, glomerulonephritis, hepatic disease

Spherocytes

Immune mediated hemolytic anemia


Following transfusions

Basophilic Stippling

Residual RNA


Lead poisoning

Howell-Jolly bodies

splenic disorders

Heinz bodies

denatured hemoglobin


Oxidant drugs and chemicals


Lymphosarcoma, hyperthyroidism, diabetes mellitus = cats


Garlic, onions, drugs, inherited disorders = dogs

Nucleated RBC's

Immature cells during anemia