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31 Cards in this Set
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- Back
Neutrophil |
Phagocytosis Seen in infection and inflammation Most abundant WBC in mammals |
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Heterophils |
Similar to neutrophils but found in birds, reptiles, and some fish |
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Eosinophils |
Capable of phagocytosis Function is modulation of immune system Seen in allergies and parasitic infections or infestations |
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Basophils |
More numerous in horse and cattle Function is mediation of immune system Indicate inflammation or infectious conditions |
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Lymphocytes |
Most abundant WBC in ruminants Production of antibodies Indicate viral infections |
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Monocytes |
Phagocytosis Indicate chronic infection |
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Pelger-Huet anomaly |
Congenital defect Have problems with bones and die young |
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Hypersegmentation |
Can be due to aging either in vivo or in vitro Prolonged storage Patients on steroids |
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Dohle Bodies |
Often seen with toxic granulation Remnants of rough endoplasmic reticulum |
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Toxic granulation |
Bacterial infection, inflammation, drug toxicity |
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Reactive Lymphocytes |
Usually caused by antigenic stimulation |
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Smudge cells |
AKA basket cells caused by disease or error |
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Rouleaux |
Stacking Artifact of prolonged storage Increased TS may be seen |
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Autoagglutination |
Clumping Occurs in immune mediated hemolytic anemia |
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Macrocytes |
Problems with synthesis of blood cells folic acid deficiency |
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Microcytes |
Iron deficiency |
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Polychromasia |
Young cells |
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Hypochromasia |
Insufficient hemoglobin Iron deficiency |
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Hyperchromasia |
Greater than normal mean corpuscular hemoglobin concentration |
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Target cells |
Iron deficiency anemia Various forms of liver disease Hypothyroidism Blowing on wet smear |
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Ghost cells |
Rupture of cell membrane - hemoglobin has leaked out Immune mediated hemolytic anemia |
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Poikilocytes |
Abnormally shaped RBC's |
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Schistocytes |
RBC fragments Trauma due to intravascular shearing |
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Acanthocytes |
Hemangiosarcoma = dog hepatic lipidosis = cat |
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Echinocytes |
Artifact of slow drying Renal failure, lymphosarcoma, snake bite |
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Keratocytes |
Hemangiosarcoma, neoplasia, glomerulonephritis, hepatic disease |
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Spherocytes |
Immune mediated hemolytic anemia Following transfusions |
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Basophilic Stippling |
Residual RNA Lead poisoning |
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Howell-Jolly bodies |
splenic disorders |
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Heinz bodies |
denatured hemoglobin Oxidant drugs and chemicals Lymphosarcoma, hyperthyroidism, diabetes mellitus = cats Garlic, onions, drugs, inherited disorders = dogs |
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Nucleated RBC's |
Immature cells during anemia |