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91 Cards in this Set
- Front
- Back
All helmiths are found in the SI, except this one which is found in the LI
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Trichuris
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How is T.canis transmitted from mom
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placenta
milk |
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How is T.cati transmitted from mom
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milk
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Where do T.canis and T.cati migrate in the 4-legged body
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hepatic
pulmonary +/- ocular |
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TX repeated for T.cati/T.canis
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Should be repeated in 2-3 weeks.
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How should pregnant ******* be TX for T. cati/T.canis?
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Fenbendazole daily from day 40 to 2 d post whelp
Two doses of moxidectin |
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How are hookworms acquired?
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prenatally
lactation through skin |
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This type of hookworm is MC in dogs and can cause blood loss and hemorrhagic enteritis
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Ancyclostoma canium
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This hookworm is most common in Southern USA
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Ancylostoma brazilense
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This hookworm is MC in cats but is still rare?
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Ancylostoma tubaeforme
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T. canis
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T. cati
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T. cati
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T. leonina
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toxocaris leonina
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This hookworm causes pedal puritis
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U. stenocephalia
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This type of tapeworm is MC
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Dipylidium canium
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What is the intermediate host of Dipylidium canium?
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fleas
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TX for tapeworms?
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Adequate flea control
Praziquantel |
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This parasite rarely causes C/S but can with concurrent infections.
They are also self limiting infections. |
Isospora
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TX for Isospora
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Sulfadimethoxime or TMS
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isospora canis
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Cryptosporidium
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This organism is an obligate intracellular self limiting diarrhea in dogs/cats
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Cryptosporidium
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How is Cryptosporidium diagnosed?
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very very small
fecal float with oil immersion modified acid fast stain |
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How is Cryptosporidium treated?
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No RX are consistently efficacious
Disease is self limiting |
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Where in the GI tract dose giardia live?
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SI
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How is giardia infection transmitted?
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fecal-oral
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These genotypes of Giardia infect dogs and cats and this humans
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Dogs C &D
Cats F Humans A&B |
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How long after infection are oocysts passed?
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1-2 weeks
intermittently |
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Elisa for giardia has this sensitivity and specificity
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SN 90%
SP 99% |
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Combining 3 fecals gives a 95% sensitivity for this cause of diarrhea
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SN
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TX for Giardia
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Metronidazole x5 days
with Fenbendazole x3-5d |
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What is the generic game plan for chronic ideopathic enteropathies
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antiparasites
dietary management antibiotics immunosuppression |
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What antiparasitics is used for chronic ideopathic enteropathies?
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fenbendazole
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What dietary management is used for chronic ideopathic enteropathies?
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antigen limited
inclusion of psyilium or ispaghula promotes colonic health |
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What antibitocs whould be used for chronic ideopathic enteropathies?
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tylosin
metronidazole or oxytetracycline |
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When is it appropriate for immunosuppression TX with chronic ideopathic enteropathies?
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when no underlying cause is found
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What type of hypersensitivities are food allergies (3)
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Type I - IgE
Type II -immune complexes Type IV - delayed hypersensitivty |
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What is the proposed hypothesis for food allergy/hypersensitivity?
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Breakdown of the mucoasal barrier or immune system dysregulation
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What clinical signs would one expect with food hypersensitivities?
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skin
GI issues |
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How is is food allergy diagnosed?
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dietary manipulation but dose not DDX food intollerance vs. food allergy
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What is food intollerance?
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food posioning or pharmacolgical intollerance
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What breed has documented Gluten Sensitivitie Enteropathy?
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Irish Setters - heritary
Not documented in cats |
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What occurs at the mucosa with gluten sensitivities?
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Directly toxic to the interstinal mucosa or induces an adverse immune reaction
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C/S of gluten sensitivity (in Irish Setters)
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poor weight gain
chronic intermittent diarrhea all after weaning |
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TX: for Gluten Sensitivity?
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resolution when fed a gluten free diet
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What occurs with SI bacterial overgrowth/AB resoponsive diarrhea?
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Overgrowth of bacteria occurs secondary to disorders that control bacteria #
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Dose bacterial overgrowth/AB responsive diarrhea occur in cats?
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No
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What is the hypothesis for why dogs get bacterial overgrowth/AB responsive diarrhea?
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defect in mucosal barrier
imporopre mucosal immune response change in bacteria Probably a combo of the above |
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What is the signalment for bacterial overgrowth?
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MC in young GSD
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Clinical signs for dogs with ideopathic bacterial overgrowth/AB responsive diarrhea?
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chronic intermittent diarrhea
weight loss xs gas borborygmi |
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What other diseases should be R/O before TX for ideopathic bacterial overgrowth (3)
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systemic disease
EPI parasites |
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What used to be the gold standard for diagnosing AB responsive diarrhea?
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quantative aerobic/anerobic culture of duodenal juic, but cut off point is disputed
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In theory this disease would have ___ folate and __ cobalimin.
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increase folate
decreased cobalamin SIBO |
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Bacteria synthesize this ___ and bind ____
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folate
cobalamin |
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Best way to diagnose AB responsive diarrhea:
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+ clinical response to Ab
Relapse when AB are withdrawn Remission when re-introduction of Abs elimination of other causes |
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What AB & dietary TX should be used for acute responsive diarrhea
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oxytetracycline
metronidazole tylosin dietary manipulation - digestive low fat and supplement cobalamin |
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This is a disorder of the SI that has chronic GI signs and histological evidenc of intestinal inflammation
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inflammatory bowel disease
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Etiology of IBD
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unknown
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This is the most common IBD (cell type)
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lymphcytic-plasmacytic enteritits
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For IBD in cats, what is the MC clinical sign - V or D?
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vomiting
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C/S for IBD in dogs is:
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vomiting & diarrhea
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Signalment for IBD
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middle aged - generally
intermittent signs at an early age |
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This form of IBD generally has blood or more severe disease
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eosinophillic gastroenteritis
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Etiology of IBD?
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breakdown and intollerance to luminal antigens
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How is IBD diagnosed?
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biopsy
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Ideopathic IBD diagnosed?
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diagnosis of inflammation with out obvious underlying cause
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What things should be ruled out for diagnosis of IBD?
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infectious
diet responsive AB responsive |
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What diagnostics should be performed to R/O other causes or DDX to IBD
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bloodwork
fecal/giardia folate/cobalamin immaging - rads & U/S Biopsy - endoscopically or laparotomy |
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If there is a problem with the folate, then the problem is located...
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proximal SI
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What is the gold starndard diagnosis for IBD?
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histopathology
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TX of IBD?
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dietary modification
AB immunosuppression |
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For mild IBD, what TX is appropriate?
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dietary change
metrondizale |
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For cats wtih IBD, what TX works really well?
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dietary change and metronidazole
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What type of immunosuppression is appropriate for IBD?
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prednisone
budesonide azithroprine chlorambucil cyclosporin |
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How dose budesonide work?
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it is locally active steriod. 90% is removed during the first pass in the liver
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When TX IBD, if the C/S reoccur as the steriod dosage is reduced, what drug can be added on?
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K9: azithroprim
Fe: chlorambucil |
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What is the prognosis for K9 IBD with severe disease?
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poor
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What is the prognosis for feline IBD?
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remission can be prolonged
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What should be done if TX for IBD continues to fail?
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ensure not a change of chronic infection to LSA
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Besides, ideopathic, what are other causes of lymphocytic plasmacytic enteritis
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bacterial
toxoplasmosis |
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What breeds of dogs/cats are more prone for lymphocytic-plasmacytic enteritits?
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GSD
Shar-Peis pure bred cats |
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What age of animals tend to get lymphocytic plasmacytic enteritis
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tend to be older
> 2 years |
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WHat C/S are associated with lymphocytic plasmacytic enteritis? K9? Fe?
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chronic diarrhea
weight loss Vomiting - cats |
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What is Basenji Enteropathy?
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severe heridatary form of lymphoplasmacytic enteritis
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What are the clinical signs of Basenji Enteropathy?
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Diarrhea
emaciation +/- spontaneous perforation PLE w/ hypoalbumin |
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How is Basenji enteropathy diagnosed?
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biopsy
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TX for Basenji enteropathy?
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unsucssessful and die within months of diagnosis
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This syndrome is unique to Soft Coated Wheaten Terriers
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Familial PLE/PLN or both
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TX/prognosis for Familial for wheaten PLE/PLN
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TX same for IBD
but poorer prognosis |