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22 Cards in this Set
- Front
- Back
- 3rd side (hint)
Nernst eq
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G= -nFdeltaE
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ETC
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Complex I III IV II and coQ and cytochromeC
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Complex I
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FMN oxidizer
electrons to iron sulfer to coQ with proton shuttle |
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coQ
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to complex iii with more protons out
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Complex III
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cytochrome C
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Cytochrome C to
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complex IV or cytochrome oxidase
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complex IV
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oxygen to water
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complex Ii
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protons not translocated
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P:O ratios
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NADH 2.5
malate-aspartate 2.5 succinate 1.5 glycerophosphate 1.5 |
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electron transport inhibitors
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rotenone
antimycin A cyanide Malonate (Succinate DH inhibitor) |
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uncoupling agents
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2,4 dinintrophenol
carbonyl (FCCP) |
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FF-ATPase inhibitors
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oligomycin
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rotenone
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insectide complex I inhibitor
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antimycin and myxothiazole
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complex II
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cyanide azide
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complex IV
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malonate
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complex II succinate DH competitive
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uncouplers
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rate cannot be maintained by gradient
proton ionophore |
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oligomycin
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blocks proton channel
indirectly stops electron transportby stopping atp syntehtase. uncoupler can relieve it. |
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salicylate
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uncouples at high concentrations
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riboflavin def
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FMN
FAD |
megamitochondria
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ROS
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when e transfer is blocked in complex I and III superoxides are formed
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apoptosis from
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cytochrome C
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