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272 Cards in this Set

  • Front
  • Back
Respiratory rate by late adolescence:
12-18
A decrease in arterial oxygen concetrations stimujlate chemoreceptors. the chemoreceptors stimulate the respiratory dcenter to increase
ventilation.
Hydrogen, oxygen and carbon dioxide can trigger the
chemoreceptors.
Increase _____ concentration normally stimulates respiratoins most strongly.
CO2
A specimen from the oropharynx is used for a
throat culture
A blood volume expander which provides plasma protein:
albumin
Increased HR, RR and systolic BP
Early sign of hypoxia
Acid fast bacillus AFB serial collection 3 days identifying presence of
TB
Agents that decrease the intensity and frquency of coughing episodes:
Antitussives
Prolonged gasping inspiration followed by a very short usually inefficient expiration:
Apneustics
Done to evaluate acid base balance, oxygenation, measure pH, PAO2, HcO3, BE SAO2
arterial blood sample
Shallow breaths interrupted by apnea
Biot's
Included in this: hemoglobin, hemaocrit, erythrocytes count, leukocyte, and differential white cell count:
CBC
Check for return of the ________ when pt. is post bronchoscopy:
gag reflux
Very shallow breathing and temporary apnea. Common cause include: CHF, incrase intracranial pressure, or drug OD:
Cheyne stokes
Childhood resp
25 per minute
Chilling will cause ___ O2 demand
increased
S/S
Fatigue, lethargic, clubbed fingers and toes
chronic hypoxia
Used for pts with clotting factor deficiencies:
Clotting factors and cryoprecipitate
Coughing, sneezing and intrapleural pressure al laid in the patency of the
respiratory tract
A canopy placed over the frame of the bed that delivers oxygen with a cooling mechanism:
croup tent
Lab test to identify a specific organism and drug sensitivity
culture and sensitivity
Lab test to identify origin, structure, function, and pathology of cells; three early morning specimens identify cancer in lungs and specific cell types:
cytology
Decrease body temp decreases _________ rate.
respiratory
A diet deficient in iron or folic acid causes _______ and ______ that are not formed adequately.
hemoglobin and RBCs
Exchange of oxygen and CO2 in the alveoli:
Diffusion
Do not smoke when using
bronchodilators
Muscular skeletal changes in teh chest wall reduce the size in the chest which makes the elderly inhale smaller volumes of
air
This medication causes the heart to contract more forcefully, bronchioles dilate, increase in blood flow and O2 delivery to active muscles:
epinephrine
These increase in the blood when the hematrocrit increases:
erythrocytes (RBCs)
Factor that affects the rate of O2 transport from the lungs to the tissues:
exercise
This increases metabolism which increases rate and depth of respirations:
exercise
Delivers 40-60% O2 concetration at 5-8L/m
face mask
Delivers 30-50% O2 at 4-8L/m for those who poorly tolerate a mask:
face tent
Measure oxygen in the number of liter per minute:
flow meters
As fluid filled lungs drain, pco2 incresaes and neonates take
1st breath
% of blood that is erythrocytes
hematrocrit
Necessary for the transportation of O2 to the cells
hemoglobin
O2 carrying red pigment
hemoglobin
a. ___________ increase repiratory rate and depth.
b. ____ increases rate and depth of breating.
c. ______ reduces need for oxygen
a. high altitudes
b. heat
c. cold
CO2 accumulates in the blood as with hyperventilation
Hypercarbia
Can cause hypoxia:
hypoventilation
Inadequate alveolar ventilatoin CO2 retained in the blood stream, occurs as a result of collapse of the alveoli
hypoventilation
Reduced oxygen in the blood and is characterized by low partial pressure of oxygen in arterial blood or a llow hemoglobin saturation
hypoxemia
Improves pulmonary ventilation, loosens respiratory secretions, facilitates respiratory gaseous exchange, expands collapsed alveoli, measures flow of air inhaled through mouthpiece, offers an incentive to improve inhalation
incentive spirometer
Increased body temp ______ respiratory rate
increases
Increasing the intake of ____ and ___ will promote oxygen transport and absorption.
protein and iron
In infants, lungs gradually expand with each breath reaching full inflation by ___ weeks, respriatory rate hight __________ per minutes, rates greadually decrease with age.
2


40-80
Hyperventilation deep and rapid breathing:
Kussmaul's
Stridor, harsh high pitched sound (may be heart upon inspiration), restlessness, dyspnea, abnormal breath sounds:
lower airway
The expandability or stretchability of lung tissue, necessary for normal inspiration:
lung compliance
Continual tendency of the lungs to collapse
lung recoil
Records emissions from radio isotope albumin injected intravenously as it circulates through the lung:
lung scan
The control center for rate and depth of respirations:
MEDULLA
Type of acidosis that will cause Kussmaul's breathing:
Metabolic acidosis
Low concentration 24-45% 2-6L/m
NC
Chemical that increases the heart rate, BP, peripheral vascular resistance, increasing the hearts workload, causes vasoconstriction; where vessels already are narrowed by atherosclerosis, tissue oxygenation can be impaired:
nicotine
Delivers highest O2 concentration 95-100% 10-15L/m
NRB
Catecholamine that increases BP causing vasoconstriction:
norepinephrine
Normal hematocrit in

men:

women:
Men: 40-54

Women: 37-47
Oxygen saturation below _____ is life-threatening.
70%
Risk factor for impaired blood to the tissues and for impaired oxygenation:
obesity
In older adults, the chest wall becomes more ___ and less ______.
Rigid and elastic
Delivers 60-90% O2 at 6-10L/m reservoir bag attached allows client to rebreathe about first 3rd of exhaled air
partial rebreather mask
Clapping; forceful striking with cupped hands over lung bases. This can mechanically dislodge tenacious secretions;
percussion
Type of breathing that creates a resistance to the air flowing out of the lungs, prolonging exhalation and preventing airway collapse by maintaining positive airway pressure:
Pursed lip breathing
1 unit RBCs increases hematocrit by ____%
4
Surfactant is a
lipoprotein
Volume of air inspired and expired is
tidal volume
Low pitched snoring sound during inhalation is a sign of
uper airway obstruction
Delivers 24-40-50% O2 @ 4-10L/m
venturi mask
-relativel high pitched and loud
-equal and a length
-the neck over and the trachea
tracheal breath sound
-major normal breath sound
-heard over most of the lungs
-soft and low-pitched
-inspiratory longer than expiratory sounds
-may b eharsher and slightly longer if there is rapid deep ventilation (eg post-exercise) or in children who have thinner chest walls. As well, vesicular breath sounds may be softer if the patient is frail, elderly, obese, or very muscular
Vesicular Breath Sounds
-very loud, high-pitched and sound close to the stethoscope
-gap between the inspiratory and expiratory phases of repiration
-expiratory sounds arelonger than the inspiratory sounds. If these sounds are heard anywhere other htan over the manubrium, it is usually an indication that an area of consolidation exists (ie space that usually contains air now contains fluid or solid lung tissue).
Bronchial Breath Sound
-intermediate intensity and pitch
-equal in length
-best heard in teh 1st and 2nd ICS (anterior chdest) and between the scapulae (poster chest) - ie over the mainstem bronchi.
-As wieh bronchial sounds, when these are heard anywhere other than over the mainstem bronchi, they usually indicate an area of consolidation.
Bronovesicular Breath Sound
Normal value:
Sodium
1.35-1.45 mEq
Normal value:
potassium
3.5-5.0 mEq
Normal value:
calcium
4.5-5.5 mEq
Normal value:
magnesium
1.5-2.5 mEq
Normal value:
phosphate
1.8-2.6 mEq
Normal value:
serum osmolarity
280-300mosm/kgh2o
Normal value:
urine pH
4.6-8.0
Normal value:
urine specific gravity
1.005-1.030
Normal value:
pH
7.35-7.45
Normal value:
Sodium
1.35-1.45 mEq
Normal value:
potassium
3.5-5.0 mEq
Normal value:
calcium
4.5-5.5 mEq
Normal value:
magnesium
1.5-2.5 mEq
Normal value:
pao2
80-100mmhg
Normal value:
paco2
35-45mmhg
Normal value:
hco3
22-26meq/l
Normal value:
base excess
-2 to +2 mEq/l
Normal value:
O2 sat
95-98%
% of body weight = H2O

full term newborn
70-80%
% of body weight = H2O

1 year
52-60%
% of body weight = H20

puberty to 39
52-60%
% of body weight = H2O

40-60 years
47-55%
% of body weight = H2O

over 60
46-52%
Average Daily Fluid Requirements:

3 days 3.0kg
250-300 mL/24hr
Average Daily Fluid Requirements:

1 yr 9.5kg
1150-1300 mL/24hr
Average Daily Fluid Requirements:

2 yr 11.8kg
1800-2000 mL/24hr
Average Daily Fluid Requirements:

6 yr 20.0kg
1800-2000 mL/24hr
Average Daily Fluid Requirements:

10 yrs 28.7kg
2000-2500 mL/24hr
Average Daily Fluid Requirements:

14 yrs 45.0 kg
2200 - 2700 mL/24hr
Average Daily Fluid Requirements:

18 yrs 45.o kg
2200-2700 mL/24hr
Assess skin (color, temp, moisture, turgor, edema), mucous membranes (color, moisture), eyes (firmness)*ck[]=SIADH
SIADH
Dehydration in children:

Weight Loss:
Mild dehydration:
Moderate dehydration:
Severe dehydration:
fluid and electrolyte imbalance
Skin: grey, cold to touch, poor skin turgor
Mucous membranes: dry oral buccal mucosa, salivation absent
Eyes: sunken eyeballs, absence of tearing when crying
Anterior fontanel (infant): sunken
Shock: increase pulse, increase respirations, decrease BP
Urine: oliguria, increase specific gravity, ammonia odor
Alterations in consciousness:irritability, lethargy, stupor, coma poss., seizures, metabolic acidosis or alkalosis
Mild: 5%
Moderate; 5-9%
Severe: 10-15%
Extracellular most abundant cation; controls and regulates water balance:
S/S dehydration in children
Intracellular major cation in intracelluar fluids; vital electrolyte for skeletal, cardiac and smooth muscle activity, also acid base balance:
sodium Na+
Cation mostly found in skeletal system:
potassium K+
Cation found mostly in skeleton, intracellular fluid, neuromuscular, cardiac function:
Ca2+
calcium
Carried nutrients to and from the the cells; fluid found outside the cells accounts for 1/3 of total body fluid:
magnesium
Mg2+
Intravascular extracellular fluid
extracellular fluid
interstitial extracellular fluid
plasma
transcellular fluid
lymph
Average fluid output:
cerebrospinal, pleural peritoneal, synovial fluids
Average fluid output/hr
1400-1500ml
The movement of the bone away from the midline of the body:
30-50ml
Evaluates pts. acid-base balance and oxygenation; composed of pH, PaO2, PaCO2, OCO3, base excess, O2 sat:
abduction
Substances combine with a carrier on the outside surface of the cell membrane and they move to the inside surface of the cell membrane:
ABGs
The movement of a substance across a cell membrane against its concentration gradient (from low to high concentration). In all cells, this is usually concerned with accumulating high concentrations of molecules that the cell needs, such as ions, glucose and amino acids
active transport
Substance produced in the posterior pituitary gland and is a major controller of fluid balance:
ADH - Anti-diuretic hormone
System that promotes sodium and water retention in the distal nephron:
ADH
Edema that is generalized throughout the body as a result of over loading of vascular fluid compartment; a generalized edema throughout the body:
Aldosterone
Ion that carries a charge; chloride, HCO3 (bicarbonate), HPO4 (phosphate), SO4 (sulfate):
anasarca
These can cause metabolic alkalosis with N/V and convulsions:
anions
Regulates water excretion from the kidney, located in hypothalamus:
antacids
Accumulation of fluid in the abdominal cavity:
ascites
Released from cells in the atrium of the heart in response to excess blood volume and stretching of atrial walls; acts as a diuretic; inhibits thirst, reducing fluid intake:
ADH
anti-diuretic hormone
Forms bones bones and teeth, transmitting nerve impulses, regulating muscle contractions, maintaining cardiac pacemaker, blood clotting activating enzymes:
Atrial natriuretic factor (ANF)
-hypoparathyoidism
-acute pancreatitis
-hyperphosphatemia
-thyroid carcinoma
-inadequate Vit D intake
-malabsorption
-alkalosis
-sepsis
-alcohol abuse
calcium
-Paget's disease
-malignancy of bone
S/S hypocalcemia
Ions that carry equal charges; NA+, K+, Ca2+, Mg2+
S/S hypercalcemia
Inserted for long term IV therapy, parenteral nutrition, for chemical damaging to the veins; assess for SOB, CP, cough, hypotension, tachycardia and anxiety:
cations
Daily weights provide adequate assessment of
central lines
-hyperosmolar imbalance
-water lost from body without significant loss of electrolytes occurs in older patients because of decreased thirst sensation
-prolonged fever
-diabetic ketoacidosis
-those receiving enteral feedings with insufficient water
fluid status
Continual intermingling of molecules in liquids, gases or solids brought about by the random movement of molecules; movement of particles from an area of greater concentration to an area of lower concentration
S/S dehydration
Do not administer hypotonic fluids to pts with _____________ or ____________disease and watch for hypovolemia.
diffusion
Fluid volume excess intravascular and interstitial spaces have an increased water and sodium content; when the body starts to utilize the stored protein due to poor nutritional intake:
kidney
heart disease
Have an altered thirst response which can alter the fluid and electrolyte balance
edema
Contain various amounts of cations and anions:
Elderly
Charged particles capable of conducting electricity:
electrolyte solutions
Depends on the informational input from the labyrinth (inner ear), vision and from stretch receptors of muscles and tendons:
electrolytes
Fluid in the interstitial space; accounts for 1/3 total body fluid:
equilibrium
Process whereby fluid and solutes move together across a membrane from one compartment to another, moves from high pressure to low pressure:
ECF
Body retains both water and sodium (hypovolemia) caused by excessive sodium chloride intake, administering infusions too fast, disease process that alters the regulatory mechanisms (eg: CHF, renal failure, cirrhosis of liver, Cushing's syndrome):
filtration
1. body alignment (posture)
2. joint mobility
3. balance (stability)
4. coordinated movement
fluid volume excess
Body loses both water and electrolytes from the ECF
four basic elements of normal body movement
Produced by the body in response to a specific antigen called an antibody:
Fluid Volume Deficit (FVD)
Measures % of whole blood composed of RBCs; increase with severe dehydration; decrease with severe over hydration; norm in males 40-50% and females 37-47%:
globulin
Major component of EBCs; increases with dehydration:
hematocrit
Homeostatic mechanisms that regulate the body fluids:

1.
2.
3.
4.
5.
6.
hemoglobin
Body's measurement of acidity and alkalinity:
1. kidneys
2. endocrine system
3. cardiovascular system
4. lungs,
5. GI
6. hormone
The pressure exerted by fluid within a closed system of the walls of a container in which it is contained:
hydrogen ion concentration
S/S include:
acidosis
weakness and lethagry
risk for dysrhythmias
coma
hydrostatic pressure
S/S include:
lethargy
weakness
anorexia
N/V
constipation
polyuria
dysrhythmias
hypercholoremia
S/S include:
GI hyperactivity
diarrhea
irritability
apathy
confusion
muscle weakness
hypercalcemia
S/S include:
N/V
muscle weakness
paralysis
decrease BP
bradycardia
hyperkalemia
S/S include:
thirst
tongue red, dry, swollen
weakness
fatigue
decrease in LOC
disorientation
convulsions
hypermagnesium
S/S include:
tingling around the mouth, fingertips
muscle spasms
tetany
hypernatremia
D5NS
D51/2NS
D5LR
hyperphosphatemia
Higher osmolarity than bodyfluids eg: 3% sodium chloride
hypertonic solutions
TPN is what type of solution?
Hypertonic solutions
Body retains both water and sodium:
Hypertonic
S/S include:
numbness and tingling in extremities
cramps
hypervolemia
S/S include:
Excess loss of Ca2+ through the GI tract, kidneys or sweating
hypocalcemia
S/S include:
muscle weakness
leg cramps
fatigue
lethargy
anorexia
N/V
decreased bowel sounds
cardiac dysrhythmia
ABs may show alkalosis
hypochloremia
S/S includes:
chronic alcoholism
renal failure
adrenal insufficiency
neuromuscular irritability
positive Chvostek and Trousseau's sign
hypokalemia
S/S include:
lethargy
confusion
apprehension
muscle twitching
abdominal cramps
anorexia
vomiting
nausea
HA
hypomagnesium
S/S include:
muscles weakness
pain
mental changes
possible seizures
hyponatremia
What type of solutions are
1/2NS
1/3NS
Hypophosphatemia
Lower osmolarity than body fluids eg: 0.45% sodium chloride
hypotonic
Fluid lost from the intravascular compartment:
hypotonic
Hypovolemia patients should be on what type of diet:
hypovolemia
Infants and growing children have a greater fluid turnover due to increase __________ rate which can affect fluid and electrolyte balance.
low sodium
_____________ is swelling, coolness, pallor and discomfort at the site.
metabolic
Perspiration looses 300-400 ml per day
Exhaled air looses 300-400 ml/day
Feces looses 100 ml
infiltration
Fluid that surrounds cells and includes lymph:
insensible losses
Fluid within all of body; 2/3 of total body fluid; contains O2, dissolved nutrients, excretory products of metabolism (such as carbon dioxide and charged particles called ions):
interstitial
Contains solutes, O2, electrolytes and glucose; provides medium which metabolic process of cells takes place:
intracellular fluid
Largest fluid compartment in an adult:
intracellular fluid
Found within vascular system; plasma
Intracellular
Involves muscle contraction or tension against resistance:
intravascular
Static or setting; there is a change in muscle tension but no change in muscle length and no muscle or joint movement (cast, traction):
isokinetic
Dynamic - muscle shortens to produce muscle contraction and active movement
isometric
Same osmolarity as body fluids eg: NS
isotonic
Includes:
NS
LR (treats metabolic acidosis)
5% dextrose in water
D5W
isotonic
Excessive loss from GI tract; can be caused from long term diuretic use, chronic alcohol abuse, pancreatitis, burns:
isotonic solutions
Can be caused from abnormal retention of, renal failure, adrenal insufficient
hypomagnesium
Regulates cardiac functions, transmits nerve impulses, relaxes muscle contractions, intracellular metabolism:
hypermagnesium
This acidosis can be caused by severe diarrhea:
magnesium
pH less than 7.35, PaCO2 less than 38, Kussmaul's respirations, lethargic, confusion, HA, weakness, N/V, monitor ABGs, I/O, LOC, administer IV sodium bicarb carefully, treat underlying problem:
metabolic
pH greater than 7.45, PACO2 greater than 45mmhg, decreased rate and depth, dizziness, hypertonic muscles, monitor I/O, LOC, V/S, IV fluids:
metabolic acidosis
Water lost through respirations, skin and feces; approximately 1300ml
metabolic alkalosis
Pulling force exerted by colloids:
obligatory losses
Loss or gain of water only; osmolarlity of serum is altered:
oncotic pressure
Movement of H2O across cell membranes from less concentrated solution to the more concentrated solution; important to maintain homeostasis:
osmolar
The power of a solution to draw water across a semi-permeable membrane
osmolarity
Hyposmolar imbalance of water intoxication is gained in excess of electrolytes resulting in low serum osmolarity and low serum sodium levels;water drawn in cells makes them swell:
osmotic pressure
Warmth or redness over the vein; inflammation of the vein:
over-hydration
Major anion of intracellular fluids, absorbed from intestines; involved in metabolism of fats, proteins, carbs:
phlebitis
Causes:
- TPN can cause it to shift into the cells from ECF compartment
- ETOH withdrawl
- acid/base imbalance
phosphate
Shifts out of cells
Ex:
- tissue trauma
- chemo
- renal failure
- infants fed cow milk
hypophosphatemia
Major cation in the intracellular fluid
hyperphosphatemia
-Maintains ICF osmolarity
-Transmits nerve and other electrical impulses
-Regulates cardiac impulses and muscle contraction
-Regulates acid base balance
potassium
Causes include:
- Vomiting
- Diarrhea
- Gastric suctioning
-Diarrhea
- Heavy perspiration
- Diuretics
- Hyperaldosteronism
- Hyper-renal failure
- Hypoaldosterone
- Excess or rapid infusions of K+
Potassium
This may occur in pts who are newly diagnosed with diabetes or in the individual who either did not administer enough insulin or the body requirements exceeded the supply available:
Hypokalemia
The body will demand more insulin whenever faced with increased physical activity or serious illness. The excessive glucose and ketones within the blood cause the serum osmolarity to rise. Water will begin to exit the cells to dilute the blood and make it less hypertonic. The cells become dehydrated and the patient will develop neurological changes. Glucose and ketones will spill over into the urine causing an osmotic diuresis to occur within the kidneys. This compounds the original problem as now the cells must release more of their water and potassium, phosphate and magnesium. Acidosis promotes potassium moving out of cells to buffer the pH change (hydrogen moves into the cells, potassium moves out).
Diabetic ketoacidosis (DKA)
S/S include:
-polyuria
-hypotension
-weight loss
-tachycardia
-fatigue
-irritability, lethargy, coma
-N/V
-initially signs of hyperkalemia
-dry, flushed skin
- dry mucus membranes
- hypokalemia p insulin administration
Diabetic Ketoacidosis
Treatment:
- Rehydration usually with NS then D5W
- Rapid-acting insulin
- Restoration of electrolyte balance (Na with NS; K+ levels can shift from hyper to hypo p admin of insulin (causes K+ to shift back into the cells)
- IV bicarbonate: given if pH <7.1. It's use is controversial as insulin therapy will correct the low bicarbonate levels
- Treat Underlying cause: e.g. infection
diabetic ketoacidosis
Caused by most often by too little ADH produced by the pituitary gland or occasionally by the inability of the kidneys to respond to ADH. Patients will excrete large amounts (5 to 40 liters per day) of extremely dilute urine. They are at risk of serious complications as vascular volume quickly falls, serum osmolarity rises and hyponatremia results. Also as serum osmolarity rises, patients become prone to thromboemboli.

Most often caused by tumors or injury of the pituitary gland or cerebral death:
Diabetic ketoacidosis
S/S include:
- polyuria
- signs of dehydration such as dry mucous membranes, poor skin turgor, hypotension, tachycardia
- urine osmolarity decreased < 200
- urine specific gravity > 300
- serum sodium > 147 mEq/L

Risk Factors:
- head injury
- pituitary tumors
- brain death
- increased ICP
Diabetes Insipidus
Treatment:
- Rapid rehydration with hypotonic saline to correct fluid losses then replacement is tailored to urinary losses
- Exogenous vasopressin (DDAVP)
- Chlorpropamid (stimulates ADH release)
Diabetes Insipidus
Stimulated by:
- Increased plasma volume as sensed by stretch recptors located in the left atrium & pulmonary vasculature & decreased BP as sensed by pressure receptors located in the carotid arteries
- During these times increased ADH release occurs which causes the kidneys to conserve water. This extra water expands in the serum & decreased serum osmolarity & sodium levels. Decrased serum osmolarity causes water to move into first the extracellular space then the intracellular spaces, causing the brain to swell - causing increased ICP.
- The increase in ECF causes an increase in aldosterone secretion which further reduces serum Na levels. Without prompt treatment the pt. will experience increased ICP due to cerebral edema & severe hyponatremia which may be fatal.
- common in ICU settings
Diabetes Insipidus
Risk Factors:

- Oat cell carcinoma of the lung; carcinoma of the pancreas, duodenum, prostate, or thymus, and some forms of leukemia
- fear, pain or stress
- head trauma, brain tumors, intercranial hemorrhage, meningitis
- positive pressure ventilation (stimulates pressure receptors in the carotid sinus & aortic arch)
- medications such as chlorpropramide, acetaminophen, morphine, amitriptyline, thiazide diuretics, CA, chemotherapy drugs
SIADH

Syndrome of Inappropriate Secretion of Anti Diuretic Hormone
Low level indicates depressed immune system:
lymphoyte
Causes serum and cellular fluid overload but not interstitial overload. This can be seen by fingerprint edema (when a finger is pressed over the sternum a fingerprint will be left).
Pts at risk for electrolyte imbalances
- COPD
- CHF
- kidney disease
- CA
- ileostomy
- elderly
- young
- fever
- surgery
- homeless
________ and _______________
Rate of bone loss is slowed with regular exercise in __________ and _________.
Renin-angiotensin
Receptors in juxtaglomerular cells in kidneys causing sodium and water retention:
Respiratory alkalosis
-pH > 7.45
-PACO2 < 35mmhg
-C/O
- SOB
- CP
- chest tightness
- difficulty concentrating
- blurred vision

- Monitor
- V/S
- ABGs

- Assist client to
- Breath more slowly
- Breath in paper bag
- Apply NRB
Respiratory acidosis
- pH < 7.35
- PaCO2 > 45mmhg
- S/S
- increase HR
- increase RR
- dizziness
- confusion
- decrease LOC
- convulsions
- warm flushed skin

- Assess
- Respiratory status
- lung sounds

- Monitor
- Airway
- I/O
- V/S
- ABGs
- Narc antagonists

- Maintain
- Adequate hydration
Sodium
Major cation in the ECF:
sodium
- Renal absorption or excretion
- aldosterone increase it
- re-absorbed in collecting ducts of nephrons
- Regulates ECF volume and distribution
- Maintains blood volume
- Transmits nerve impulses and contracts muscles
Hyponatremia
Causes:
- GI fluid loss
- sweating
- diuretics
- hypotonic tube foods
- drinking water
- excess IV D5W
- head injury
- AIDS
- Malignant tumors
hypernatremia
Causes
- Loss of fluids
- hyperventilation
- diarrhea
- water deprivation
- excess salt intake
- heat stroke
Stress
________ increases cellular metabolism blood glucose concentration, catecholaminelevels.
Stress
_______ can increase ADH and decrease urine output.
water excess
Sudden weight gain, blurred vision, H/A, and decreased fluid output compared to intake is an early sign of
Surgery
______________ can affect the body's ability to maintain fluid.
gauge
The diameter of the lumen is the _______ of the needle.
kidneys
The ___________ are the primary regulator of body fluids and electrolytes.
potassium
The ____________ is the organ that assumes the greatest responsibility for the __________________ balance.
1500 ml
2500 ml
1000 ml
The normal fluid intake is _____________ ml. We need _______________ ml. We get an extra _______ ml from the food taken in during metabolic process.
Third space syndrome
The fluid shifts from the vascular space into an area where it is not readily accessible as ECF.
Thirst mechanism
_______________ is the primary regulator of fluid.
Volume expanders
These are used to increase blood volume following severe loss of blood. Examples are Dextran, plasma and human serum albumin.
Anti-diuretic hormone
You are at risk for dehydration if you have a decrease in
Respiratory acidosis
Risk factors include:
-alveolar gas exchange impairment (pneumonia, acute pulmonary edema, aspiration, near-drowning)
-chronic lung disease (asthma, CF, emphysema
-OD narcotics/sedatives that depress respiration
-brain injury

Manifested by:
-PaCO2 above 45 mmHg
-pH < 7.35
Respiratory alkalosis
Risk Factors:
-Hyperventilation (anxiety, increased body temp, overventilation via mechanical vent, hypoxia, salicylate OD)

Manifested by:
-light-headedness
-pH >7.45
-PaCO2 35 mmHg
Metabolic acidosis
Risk Factors include:
-Increased nonvolatile acids in the blood (renal impairment, diabetes mellitus, starvation)
-Decreased bicarbonate (prolonged diarrhea)
-Excess IV of NaCl

Manifested by:
-Kussmaul's respirations
-pH <7.35
-serum bicarbonate<22 mEq/L
Metabolic alkalosis
Risk Factors include:
-Excess acid loss (vomiting, GI sx)
-Excess use of potassium-losing diuretic
-Excess adrenal corticoid hormones (Cushing's syndrome, hyperaldosteronism)
-Excess bicarbonate intake (antacids, parenteral NaHCO3)

Manifested by:

-tetany
-dizziness
-dizziness
-decreased RR and depth
-pH > 7.45
-serum bicarbonate > 26 mEq/L
Acid base balance
-Relationship is critical for homeostasis
-Significant variations from normal pH ranges are notwell tolerated and may be life threatening
-Balance is achieved by Respiratory and Renal systems
H2CO3 Carbonic acid

NaHCO3 Base bicarbonate
There are two buffers and they work in pairs:

Associated with the respiratory and renal compensatory system
CO2
Approximately 98% normal metabolites are in the form of
kidneys
Metabolic element of the acid base balance is a function of the
H+
Na+
anhydrase
Process of kidneys excreting ____ into the urine and reabsorbing ____ into the blood from the renal tubules
1) active exchange ______ for H+ between the tubular cells and glomerular filtrate
2) carbonic _________ is an enzyme that accelerates hydration/dehydration CO2 in renal epithelial cells
H2CO3
Acid Base Relationship

H20+CO2 = ______ = HCO3 + H+
pH: 7.35-7.45
PCO2: 35-45 mmHg
PO2: 80-100 mmHg
HCO3: 22-26 mmol/L
BE:-2 - +2
SaO2:>95%
Normal ABGs:

pH:
PCO2:
PO2:
HCO3:
BE:
SaO2:
pH: <7.35
PCO2: >45
HCO3:<22
Acidosis:

pH:
PCO2:
HCO3:
pH: > 7.45
PCO2: < 35
HCO3:> 26
Alkalosis:

pH:
PCO2:
HCO3:
causes of Respiratory acidosis
- emphysema
- drug OD
- narcosis
- respiratory arrest
- airway obstruction
Respiratory acidosis
- think of CO2as an acid
- failure of the lungs to exhale adequate CO2
- pH <7.35
-PCO2 > 45
- CO2 + H2CO3 - decreased pH
Metabolic Acidosis
-Failure of kidney function
-Decreased blood HCO3 which results in decreased availability of renal tubular HCO3 for H+ excretion
-pH < 7.35
-HCO3 <22
Causes of Metabolic Acidosis
-renal failure
-diabetic ketoacidosis
-lactic acidosis
-excessive diarrhea
-cardiac arrest
Respiratory Alkalosis
-too much CO2 exhaled (hyperventilation)
-decreased PCO2, H2CO3 insufficiency = increased pH
-pH > 7.45
- PCO2 < 35
Causes of Respiratory Alkalosis
-hyperventilation
-panic d/o
-pain
-pregnancy
-acute anemia
-salicylate OD
Metabolic Alkalosis
-Increased plasma bicarbonate
-pH > 7.45
- HCO3> 35
Causes of Metabolic Alkalosis
-increased loss acid from stomach or kidney
-hypokalemia
-excessive alkali intake
PO2 NL = 80-100 mmHg

pH NL = 7.34-7.45
acidotic <7.35
alkalotic>7.45

PCO2 NL = 35-45 mmHg

HCO3 NL = 22-26 mmol/L
acidotic <22
alkalotic >26
Analyzing an ABG:

1. PO2: NL = ______
2. pH NL = ________
3. PCO2 NL = _________
4. HCO3 NL = ________
step 1: 80
step 3: abnormal & NL
abnormal & NL

step 4: pH
HCO3
Analyzing an ABG:

Step 1:

1. Determine PaO2 & SaO2
2. Determine oxygen status
3. Low PaO2 (< ____mmHg) means hypoxia
4. NL/elevated oxygen means adequateoxygenation

Step 2:
pH acidosis < 7.35
alkalosis >7.45

Step 3:
Study PaCO2 & CHO3
Respiratory irregularity if PaCO2 _______ & HCO3 _____
Metaboic irregularity if HCO3 ______ & PaCO2 ____

Step 4:
Determine if there is a compensatory mechanism working to try to correct the _____. (ie: If have primary respiratory acidosis will have increased PaCO2 and decreased pH. Compensation occurs when the kidneys retain _______.
Respiratory Acidosis:

pH = 7.30
PaCO2= 60
HCO3= 26
Respiratory Acidosis:

pH =
PaCO2=
HCO3=
Respiratory Alkalosis:

pH = 7.50
PaCO2= 30
HCO3= 22
Respiratory Alkalosis:

pH =
PaCO2=
HCO3=
Metabolic Acidosis:

pH = 7.30
PaCO2= 40
HCO3= 15
Metabolic Acidosis:

pH =
PaCO2=
HCO3=
Metabolic Alkalosis:

pH = 7.5
PaCO2= 40
HCO3= 30
Metabolic Alkalosis:

pH =
PaCO2=
HCO3=
alkalosis
Compensations:

Respiratory acidosis and metabolic _______________
acidosis
Compensations:

Respiratory alkalosis and metabolic _______________
kidneys
In respiratory conditions, the _______ will attempt to compensate and visa versa.
kidneys
HCO3
In chronic respiratory acidosis (COPD), the __________ increase the elimination of H+ and absorb more ________. The ABG will show NL pH, increase CO2 and increase HCO3.
minutes
24 hours
5 days
Buffers kick in within________. Respiratory compensation is rapid and starts within minutes and complete within _____ hours. Kidney compensation takes hours and up to ______ days.
physiologic condition
Valuable information can be gained froman ABG as to the patients
protein, calories, fiber