Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
67 Cards in this Set
- Front
- Back
|
who are the classic victims for EGUS
|
racehorses
show horses STALLED horses |
|
|
EGUS CS adults
|
mild intermittent colic cincides with meals
decreased appetite faiure to finsh grain loss of body conditino poor hair coat alterations in attitude |
|
|
which feed will a EGUS horse walk away from first hay or grain
|
grain, increases too much acid
|
|
|
will you see changes in your blood work with EGUS
|
no, you might see anemia and hypoproteinemia in SMALL animals not horses
|
|
|
EGUS CS foals
|
gastric/duodenal ulcr dz
neonates weanling 1' risk facts hypoxemia- most common. low O2 at birth NSAIDs hospitalization stress |
|
|
what can be stressful to a foal
|
weaning!!
|
|
|
EGUS foals CS
|
mild to severe pain
bruxism/ptylalism- adult horses don't grind their teeth |
|
|
treatment of EGUS for adults
|
dec. concentrate inc roughage
H2 receptor antagonists (cimitide/ranitidine) H+ pump inhibitors (omeprazole) sulcrafate |
|
|
do horses have both lesions in the glandular and mucosal stomach?
|
can have both or one without the other
|
|
|
what is supposed to live in the equine stomach?
|
the feed bolus
|
|
|
what can be stressful to a foal
|
weaning!!
|
|
|
EGUS foals CS
|
mild to severe pain
bruxism/ptylalism- adult horses don't grind their teeth |
|
|
treatment of EGUS for adults
|
dec. concentrate inc roughage
H2 receptor antagonists (cimitide/ranitidine) H+ pump inhibitors (omeprazole) sulcrafate |
|
|
do horses have both lesions in the glandular and mucosal stomach?
|
can have both or one without the other
|
|
|
what is supposed to live in the equine stomach?
|
the feed bolus
|
|
|
EGUS d/dx
|
gastric impactation
gastric neoplasia (SCC) signalment!! young horses in competition |
|
|
EGUS d/dx
|
gastric impactation
gastric neoplasia (SCC) signalment!! young horses in competition |
|
|
what if endoscopy is not available for EGUS during treatment
|
reponse to therapy may be considered diagnostic
improvement in attitude weight gain resolution of colic improved coat condition |
|
|
what if endoscopy is not available for EGUS during treatment
|
reponse to therapy may be considered diagnostic
improvement in attitude weight gain resolution of colic improved coat condition |
|
|
what is a test you can do on the feces to see if you have eradicated the ulcers
|
occult : Abs against hemoglobin and albumin
|
|
|
what is a test you can do on the feces to see if you have eradicated the ulcers
|
occult : Abs against hemoglobin and albumin
|
|
|
what are you going to treat colic pain with
|
ban amine don't use this in EGUS patients
|
|
|
what are you going to treat colic pain with
|
ban amine don't use this in EGUS patients
|
|
|
what is xylazine going to do if you accidentally inject yourself
|
its gonna kill you dial 911 youre going to unconscious very soon
|
|
|
what is xylazine going to do if you accidentally inject yourself
|
its gonna kill you dial 911 youre going to unconscious very soon
|
|
|
how effective are antacids in horsses
|
they aren't you need sooo much and its not worth it
|
|
|
where do H2 receptor antagonists work
|
at parietal cells at the histamine receptor
|
|
|
what is ranitidine how often is it given PO
|
its an H2 receptor antagonist given every 8 hours can take up to 4-6 weeks for resolution
|
|
|
what is the new treatment of choice for EGUS
|
omeprazole once a day in a paste form
expensive its the only approved/ licensed TX to treat and PREVENT EGUS |
|
|
what kind of drug is omeprazole
|
H+ pump inhibitor works at H/K atpase pump
|
|
|
what do you use carafate for
|
band aid for ulcer
stimulates PG activity can interfere with other drugs |
|
|
will you use carafate as your primary treatment for EGUS
|
hell no its not that good
|
|
|
what is in the lower half of the stomach that protects squamous epithelium from exposure to HCl and bile acid
|
forage ball
|
|
|
which part of the stomach has limited defenses against gastric acid
|
squamous mucosa
|
|
|
when do squamous lesions occur
|
with decreased feed intake or limited forage
|
|
|
which part of equine stomach has defenses again gastric acid?
|
glandular mucosa has many defenses against gastric acid
|
|
|
what does the glandular mucosa have that protects it from gastric acid
|
mucus barrier and HCO3- secretion
rapid regeneration and repair reflux from the duodenal secretions neutralizes HCl |
|
|
how does diet effect gastric secretion
|
inc. time between meals inc. acid
grain feeding inc. acid-> dec. saliva -> dec. feed ball -> inc. VFA's in gastric fluid-> inc HCl damage to squamous mucosa |
|
|
what benefits do legumes have for gastric protectants
|
have greater buffering effect and protects squamous epithelium from exposure to HCl
|
|
|
what effect does exercise have on the stomach
|
dec. pH in the upper portoin of the stomach. sloshing effect of HCl up into squamous mucosa
|
|
|
what is EGUS
|
term for clinical finding of ulcers in the equine stomach
erosions/ulcers of squamous epithelium along margo plicatus lesionsi in glandular mucosa and pylorus |
|
|
what happens to the stomach with NSAID toxicity?
|
PG's important for mucosal blood flow and cytoprotective barrier are impaired
|
|
|
is there any correlation between the presence of squamous and glandular lesions?
|
no
|
|
|
what is the treatment of pyloric dz
|
more difficult than squamous ulcer dz
may require prolonged therapy dietary modifications prophlactic anti-ulcer therapy may be beneficial gastro guard (omeprazole) |
|
|
which part of the stomach has limited defenses against gastric acid
|
squamous mucosa
|
|
|
what is located in the lower part of the stomach that protects the squamous epithelium from HCl and bile acids
|
forage ball
|
|
|
when are squamous lesions common ?
|
when you stop feeding horses, their forage ball goes away
|
|
|
which part of the stomach has defenses against gastric acid?
|
glandular mucosa
|
|
|
what does the glandular stomach have that protects it from HCl and bile acids?
|
mucus barrier and HCO3- secretion
|
|
|
reflux of what into the stomach will neutralize HCl
|
duodenal secretions from pancreas and liver
|
|
|
what will decrease saliva production ?
|
increasing time between meals
grain feeding |
|
|
what will increase pH
|
legumes
|
|
|
what decreases pH
|
grain
strenuous exercise |
|
|
what is EGUS
|
term for finding ulcers in the equine stomach
|
|
|
where are erosions and lesions in the equine stomach when there are ulcers ?
|
erosions/ulcers in the squamous epithleium along margo plicatus
lesions in glandular mucosa and pyllorus +/- duodenitis |
|
|
what produces HCl
|
parietal cells
|
|
|
what 3 things do you need to bind to receptors for HCl to be produced
|
gastrin, acetylcholine and histamine
|
|
|
what secretes HCO3-
|
goblet cells in the glandular mucosa
|
|
|
what does PGE2 encourage?
|
mucus secretion
|
|
|
what does PGI2 encourage?
|
local vascoconstriction
|
|
|
where do foals get lesions for EGUS
|
in the glandular/ pyloric region
|
|
|
where do adult horses get lesions for EGUS?
|
squamous mucosa (non-glandular) along cardiac sphincter and margo plicatus
|
|
|
does EGUS result in anemia or hypoproteinemia?
|
no
|
|
|
who would a fecal occult blood test be useful in, why?
|
foals, adults have bacteria that will eat the blood
|
|
|
what do NSAIDs inhibit
|
PGE2 and PGI2
|
|
|
what do H2 blockers inhibit?
|
histamine, it can't bind so no HCl produced
|
|
|
how do proton pump inhibitors work
|
they block the sodium potassium pump that allows parietal cells to release HCl
|
