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39 Cards in this Set

  • Front
  • Back

Disease Management and control

Hygeine


prevention


vaccination


veterinary surveillance


knowledge of endemic disease

Notifiable disease (equine)


- Exotic

EXOTIC:


- Equine infectious anaemia


- Rabies


- West Nile Virus


- African horse sickness


Notifiable disease (equine)


Endemic

ENDEMIC


- Contagious equine metritis


- Strep Equi Equi


- Equine viral arteritis

New disease, carried in fruit bats in Aus. Fatal to humans if in contact with urine or placental fluids. Many horse deaths. Neuro disease

Hendra Virus

Role of vets in Control of infectious disease outbreaks

1. Vacc protocol


2. animals not exposed to pathogen, PPE


3. certify health status accuratley


4. up to date with vet surveillance


Biosecurity risk of equine infectious Gastro-intestinal disease

- Leahurst do not accept suspect cases unless isolation stable free


- V detrimental to horses


- GI upset serious


- V contagious


- Hard to keep isolated with simple barrier nursing

Infectious colitis has many potential infectious causes

Salmonella enterica


Rotavirus


C. perfringens


C. difficile

Salmonella enterica causes what type of colitis

Acute fibrinonecrotic colitis

Salmonella - characteristics

Host suffers when stressed and antibiotic txGram neg


facultative anaerobe


2000 serovars


flagella and pili


adhesion


invasion genes - interiorized


3 x exo toxins effect cAMP


endotoxaemia

C. perfringens and C. difficile

Gram +


Anaeorobes, haemolytic


spore forming & hardy


ELISA/PCR to tell diff toxins


C. perf = non-motile, toxin A


C. Diff = motile, toxin b-2 (horses) and toxin A (toxic to mphage)

Rotavirus

foals, under 2mo


stres induced and stressed adults may shed


virkon will kill


VP4 coating


infect apices of villi


Bacterial causes of dermatological disease in horses

Strep. equi equi


Strep zooepidemicus


Staph A


Staph intermedius


MRSA


Dermatophilosis

Fungal causes of derm disease

Dermatophysosis - ringworm


Viral causes of derm disease

Viral papilloma - grass warts


Pinnal acanthosis


Coital exenthema - EHV-3


Horse Pox


Papular dermatosis

Sarcoids have 6 presentations

1. Occult


2. Verrucose


3. Nodular


4. Fibroblastic


5. Mixed


6. Malignant

Strep Equi zooepidemicus


Stre equi equi

opp path


obl path, strangles


- gram +, fac anaerobe, M-protein = anti pcytic

Staph A


Staph I

painful, abscesses focal and diffuse


exudative


pyoderma and pastern folliculitis (mud fever)


RESISTANT to penicillin, duh


Dermatophilosis

common, contagious, rain scald.


Get dry, and clean, peel off scabs and wash - chlorhexadine

Dermatophysosis

ringworm


contagious and common, self limiting 5-10wks


2wk incubation


topical shampoos if want


Grass wart

self limiting


viral papilloma


Aural plaques

pinnal acanthosis


blackfly vector


never rid of


no need to tx, will make worse


Coital exanthema

EHV-3


solid immunity after infection


venereal


may ulcerate so antimicrobial wash


stop breeding until healed 3wks


incubation 1 wk

Sarcoids

spread by flies


f-blast mutation


get rid asap


avoid homeo tx


radiation best


biopsy can aggravate

Neurological disease - viruses

Rabies - uncommon in horses. 3 forms


West nile virus (arbo) - terminal host = horses/man. can cause multifocal encephalomyeiltis.


Seizures in horses are fine mouth movements. Effects pyramidal tract in motor cortex = v small in horses, as control fine movements.


EHV-1 - myeloencehalopathy, rare. Ataxia, cauda equina --> flaccid tail, bladder atony. Xanthochromia of CSF.

Neuro diseases - bacteria

strangles --> abscess in brain


Bacterial meningitis


Clostridial toxins = neuro. Botulism and tetanus - VACCINATE

Neuro diseases - protozoa and parasitic

Protozoa:


- Equine protozoal myeloencephalitis (EPM)


Parasite:


- Strongylus vulgaris


- Trypanosoma

Strangles is

contagious equine rhinopharynitis

Strep equi equi host-path interaction

fomite spread


direct (sneezing)


recovered animals shed (3-6wks)


Clinical signs of strangles

incubation = 3-14d


pyrexia


mucopurulent discharge


SM and RP LN abscesses (d7)


dyspnoea


--> bastard strangles


--> purpura haemorrhagica (t3 hypersens)

Tx for strangles

PCR nasal-pharyngeal swap and culture


- 3 x ", for 3 wks = 85% free


barrier nurse/isolation


disinfect, high temp wash


dont use inf field for 2m


water (4wks), wood (8wks)


carry - 40mths


Rhodococcus equi

- foals


- supperative bronchopneumonia


- chronic and acute


- gram + cocci


- soil/commensal GIT bact - coprophagy, poor - - -- grass cover


- multiplies in alv mhages, destroys alveoli and then peyers patches as spreads.

What is hyper-immune plasma

Ab for selected Ag and virulence factors from another horse, injected into foal


short term immunity


before exposure


500ml, pregnant mare, birth and 21do


Viral respiratory diseases

Eq viral arteritis


African horse sickness


Equine Rhinovirus


EHV 1


EHV 2


Adenovirus


Influenza

Eq viral arteritis

ss, RNA


venereal and inhaled


notifiable


stallions only - Needs testost


oedema, oral papules, vascular inflam


incubation 3-14d


np swap, buffy coat analysis, serology titres



African horse sickness

oedema


proteinaceous fluid in ISF


seasonal


arbovirus


endothelial damage


3 forms: pulmonary, cardiac and mixed

INfluenza

H ag helps stick to mucosal surface


N helps cell lysis to become intracellular


N stops mucociliary esc


orthomyxovirus


incubation - 24hrs


pyrexia, nasal discharge, tachpnoea, coughing


1 week off/day ill


quarantine - 2wks


R0 =?

= number of cases that passes the disease on.


>1 = epidemic; <1 = will stop

Flu vaccines = ProteqFlu and Prequenza

ProteqFlu has 2 x recent strains + 1 x adj


Prequenza = old strains and lots of adj



3x vacc req. For dressage, last booster must have been 7d-6mth prev.

EHV-1 and EHV-4 are resp diseases

Trigeminal ganglia


Shed 2-3wks


Neonate - die; adults - latent


EHV-1 stronger and some neuro signs


INcubation - 2-10d


Oedema, nasal discharge, pyrexia


ISolate virus


Vacc at 5, 7 and 9mths old