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26 Cards in this Set
- Front
- Back
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Volume of Distribution (Vd) |
Vd = (Rx given by IV) / [Rx in Plasma] |
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Clearance (CL) |
CL = (0.7 x Vd) / t1/2 |
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Loading Dose (LD) |
LD = Css x Vd |
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Maintenance Dose (MD) |
MD = Css x CL |
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Cardiac Output (2 different equations) |
CO = SV x HR CO = (Rate of O2 consumption) / (Arterial O2 content - Venous O2 content) |
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Stroke Volume |
SV = EDV - ESV |
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Mean Arterial Pressure (MAP) -- 2 equations |
MAP = CO x TPR MAP = 2/3 Diastolic pressure + 1/3 systolic (*at resting HR only) |
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Ejection fraction |
EF = SV / EDV = (EDV - ESV) / EDV *normal > 55% |
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Physiologic Dead Space |
Vd = Vt x (PaCO2 - PeCO2 / PaCO2) |
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Pulmonary Vascular resistance |
PVR = ΔP / CO
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Pulmonary or Capillary Resistance |
R = 8nl / π r^4 where n = viscosity l = length of vessel r = radius |
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Alveolar Gas Equation |
PAO2 = 150 - (PaCO2 / 0.8) |
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What is a normal A-a gradient? |
10-15 |
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Renal Clearance |
CL = UV / P Where UV = Excretion rate |
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Filtration Fraction |
FF = GFR / RPF |
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Renal Blood Flow (RBF) |
RBF = RPF / (1 - Hct) |
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Filtered Load |
FL = GFR x [Plasma] |
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Specificity |
(**True Negative Rate**) D / D + B ... or 1 - FP |
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Sensitivity |
(**True Positive Rate**) A / A + C .... or 1 - FN |
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Positive Predictive Value (PPV) |
PPV = A / A + B |
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Negative Predictive Value (NPV) |
NPV = D / D + C |
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Odds Ratio (OD) |
(**For Case-Control Studies**) OD = AD / BC |
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Relative Risk (RR) |
(**For Cohort Studies**) RR = (A/A+B) / (C/C+D) |
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Attributable Risk (AR) |
AR = (A/A+B) - (C/C+D) *NNH = 1/AR |
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Absolute Risk Reduction (ARR) |
ARR = (C/C+D) - (A/A+B) *NNT = 1/ARR |
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Confidence Intervals |
CI = μ ± Z(SEM) *Where SEM = σ/√n *Z = 2 for 95% interval *Z = 2.5 for 99% interval |
