Epinephrine

Front 1

Epinephrine

Trade Name?

Back 1

Adrenalin

Front 2

Epinephrine

Class?

Back 2

Sympathomimetic (Sympathetic Agonist)

Front 3

Epinephrine

MOA?

Back 3

•Direct alpha adrenergic receptor stimulation
o Increased systemic vascular resistance resulting in increased BP
•Direct beta adrenergic receptor stimulation
o Positive inotropic effects increasing cardiac contractile force
o Positive chronotropic effects increasing heart rate
o Positive dromotropic effects increasing automaticity (converting fine v-fib into course v-fib) and increasing myocardial electrical activity (possibly converting asystole rhythms)

Front 4

Epinephrine

Indications?

Back 4

• Epinephrine 1:1,000 (more alpha adrenergic stimulation)
o Allergic Reaction
o Respiratory Distress
o Pediatric Respiratory Distress
• Epinephrine 1:10,000 (both alpha and beta adrenergic stimulation)
o Cardiac Arrest
o Refractory Anaphylaxis (IV 1:10,000)
o Pediatric Bradycardia
o Pediatric Cardiac Arrest

Front 5

Epinephrine

Contraindications?

Back 5

•None in emergency setting
•Epi 1:1,000 IV

Front 6

Epinephrine

Side Effects?

Back 6

•Palpations
•Anxiety
•Tremors
•Headache
•Dizzy
•N/V
•Increased Myocardial Oxygen Demands

Front 7

Epinephrine

Adult Dose / Route?

Back 7

•Epinephrine 1:1,000
Adult
•IM: 0.3 mg (if age < 50 yrs)
•IM: 0.15 mg (if age > 50 yrs)

•Epinephrine 1:10,000
Adult
 IV: 1.0 mg repeated every 3-5 minutes
 ET: double the IV dose