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22 Cards in this Set

  • Front
  • Back
What is root of word
Epi
demos
from Greek, prevalence of an epidemic disease.
epi - among, upon
logy - science, theory, study
Epidemiology definition
Study of the distribution and determinants of disease or other health outcomes in populations
what are objectives of epidemiology?
Identify disease etiology
Describe patterns of disease occurrence(how common andhow important)
Study natural history of disease(duration, prognosis, severity?)
Epidemiological approach to disease causation includes what:
1. association btw some 'exposure' amd disease?
2. is assn valid?
3. is there evidence of causality?
4. causality cannot be proven with epidemiological methods
What are three levels of Prevention in Epidemiology
1. Primary prevention -
Immunization, health education
2. secondary prevention
Screening
3. Tertiary prevention
Treatment and rehabilitation
What are branches of Epidemiology?
1. Causation - inf ds vs non-inf ds
2. Disease - Cancer, Chronic ds, Cardiovascular
3. Exposure - Genetic, Nutritional
4. Approach - Molecular, Mathematical, Clinical
Give brief ID history
1 10 biblical plagues
Plague of Athens
Antonine Plague
Black Death 1347-1350
Great Plague 1665-66
Malaria and colonies
Smallpox and defeat of indig in AMericas
yellow fever at easter ports
Spanish flu (influenza)1918
Who was the first to record "bills of mortality" - death
John Graunt during the great plague 1665.
What was significant about keeping track of the "observations" in 1662 in regard to mortality
Needed overall mortality numbers to keep track of 'plague' mortality. important chronicle. 40% of all deaths attributable to the plague
What was Graunt's contribution to Epidemiology
1st to systematically analyze the bills of mortality
Published the 'natural and political observations' on the bills of mortality
Regarded as founder of demography and modern epi
What did Dr Snow do to contribute to Epidemiology?
Used Quantitative arguments to show Cholera risk assd with contaminated water.
Showed Cholera was water-borne
He did not know the causative agent
What is the broad street story
Snow knew that nearly all deaths of Cholera were attributable to the Broad STreet Pump. He got the handle removed from the pump and stopped the epidemic
What are stages of non-clinical diseases?
Latent
Preclinical
Subclinical
Name some Chronic Carrier Status
Hep B virus (rare)
Hep C virus(carrier stat common)
Salmonella typhi (typhoid mary)
What is difference between Latent period and Incubation period
Latent is from exposure to start of infectiousness, while Incubation is from exposure to appearance of symptoms.
What are three classes of Infectious disease patterns?
Class A - Inapparent Infection Freq - tubercle bacillus
Class B - Clinical disease freq, few deaths - measles virus
Class C - Infections usually fatal - Rabies virus
What is difference between quarantine and isolation? What measures are taken in each?
Quarantine concerns clinically normal people who might have been exposed to infectious agent. Isolation concerns clinically ill(thus likely infectious) individuals. Quarantine reduces contact with healthy population. Isolation uses barrier measure to reduce contact.
What are disease outbreaks?
an epidemic with a very circumscribed scope, associated with a common vehicle or either a point source or continuous nature.
What is involved in an outbreak investigation?
Sudden unusual clusters of cases of a certain syndrome. Often associated with food.
What is case definition?
Proper case def is essential for successful outbreak investigation.
"stool culture on or after 2/1/09 yielded Salmonella....
What is usual shape of epidemic curve?
Bell shaped
l'honneur
honor