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13 Cards in this Set
- Front
- Back
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Origin or replication
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Site where replication begins
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DNA Helicase
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Unwinds DNA into replication fork
Includes DNAa and DNAb proteins |
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Topisomerases
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Prevent recoiling of DNA helix
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DNA Topisomerase I
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Creates nick, breaks backbone providing free roation
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DNA topoisomerase II
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Covalent linkage between DNA strands controlled by the enzyme
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Primase
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Adds primers to the single nucleotide strand
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SSBP's
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Stabilize replication fork
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DNA polymerase III
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extends DNA strand
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DNA polymerase I
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Removes primer on okazaki fragment and fills vacant region with DNA
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DNA polymerase alpha
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extends DNA strand by adding free nucleotides to the free 3' end (5'-3' direction)
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DNA polymerase delta
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Aids DNA polymerase alpha
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DNA ligase
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joins DNA strands and newly synthesized DNA on lagging strand by phosphodiester bonds
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Sliding clamp
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Ensures DNA polymerase is fixed to the replication fork firmly
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