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12 Cards in this Set
- Front
- Back
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Generally, Enteric Viruses Include |
Coxsackievirus Poliovirus Hepatitis A Virus Rhinoviruses Rotavirus |
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Properties of Picornaviruses genome |
Non enveloped + ssRNA linear |
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Coxsackieviruses cause |
Aseptic Meningitis Meningococcal Encephalitis & paralysis Respiratory & Febrile illness Hand-foot & mouth disease, acute hemorrhagic conjuctivitis - Cox A Myocarditis, Pericarditis, severe generalized edema in infants Cox B |
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Cox virus diagnosis |
Tissue culture Serology (antibody-immunoflorescence, antigen detection) Nucleic acid detection (RT-PCR) |
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Poliovirus has how many serotypes |
3 |
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Polio virus pathogenesis |
Fecal-oral route Through alimentary mucosa Tonsils and peyer's patches Blood stream Entry into CNS |
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Diagnosis of poliovirus |
Isolation from Stool or pharynx Oligonucleotide typing |
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HAV has how many serotypes |
1 |
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HAV transmission |
Close contact e.g. Sex Fecal-oral route Blood exposure rare |
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HAV Pathogenesis |
Ingestion Crosses intestines Blood Replication in hepatocytes & GI Epithelium Released by exocytosis into bile Stools |
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HAV clinical features |
Fever Fatigue Jaundice Dark urine Nausea and vomiting Abdominal pain |
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HAV Diagnoses |
IgM anti-HAV appear as early as two weeks n disappear 3-12 IgG anti-HAv appear 8-12 wks after inf. N remain in blood for life-long immunity |
