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9 Cards in this Set

  • Front
  • Back
Viruses in the Picornaviridae family
1. poliovirus
2. Coxsackie virus
3. Echovirus
4. Enteroviruses
Char. of picornaviradae
1. ss +RNA
2. Enveloped.
3. primary replicatory site = alimentary tract.
4. Icosahedral
5. Make polyproteins
6. Use Ig class receptors.
7. Acid stable, sensitive to formaldehyde, bleach, >50C and ionic detergents.
Route of transmission of picornaviradae viruses.
Entry via aerosol, touch, fecal ingestion...Replication in oro-pharynx & tonsil....Replication in Peyer's patches (1 viremia)...Excreted in feces or goes to 2 viremia in tissues
Seasonal peak of enteric viruses.
in NE in late winter/early spring.
Primary difference b/w CoxA and CoxB manifestations.
Cox A= meningitis, herpangina, HF& disease, respiratory illness.
Cox B= cardiac./
What is CAR?
a receptor shared by Cox B and adenovirus.
Caused by echovirus
Caused by enteroviruses
Enterovirus conjunctivitis
Respiratory illness
Char of norwalk virus.
vomiting and naseua, 2 day onset with 24 hours of severe vomiting. Primarily in older children & adults. Causes 90% of food-related gastroenteritis.