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16 Cards in this Set

  • Front
  • Back
Define this type of hormonal communication:
Intracrine
Uptake of hormonal precursor and intracellular conversion to effective hormone and subsequent binding to intracellular receptor
Define this type of hormonal communication:
Intercrine
Direct transfer of messenger molecule into adjacent cells via gap junctions
Define this type of hormonal communication:
Autocrine
Hormone secreted and interacts with receptor on the same cell
Define this type of hormonal communication:
Paracrine
Hormone released from cell and interacts with receptor on nearby cells
Define this type of hormonal communication:
Juxtacrine
Messenger molecule remains associated with cell membrane of signaling cell and interacts with receptor on adjacent cell
Define this type of hormonal communication:
Solinocrine
Messenger molecule secreted into lumen of ductal system (GI, Respiratory, Urogenital)
Define this type of hormonal communication:
Neurocrine
Two types
Synaptic - Messneger molecule traverses synaptic space
Non-synaptic - Messenger molecule is carried to site of action by ECF or blood
Define this type of hormonal communication:
Hemocrine
Traditional view of hormonal signaling. Cell dumps product into blood to activate distant cells.
What is a permissive hormonal effect?
When an initial hormone must prime the target tissue prior to it being receptive to the activating hormone
What compound acts on the thyotroph cells in the pituitary?
Thyroid Regulating Hormone
What compound acts on the thyroid follicles?
Thyroid Stimulating Hormone
What inhibits thyroid hormone production?
Thyroid hormones
Somatostatin
Thyroid stimulating hormone
What are examples of peptide/polypeptide/protein hormones?
Insulin
Growth hormone
Calcitonin
What are examples of lipid derived hormones?
Steroids (aldosterone, estradiol, cortisol)
Eicosanoids (prostaglandins, thromboxanes)
What are some examples of amino acid derived hormones?
Epinephrine
Norepinephrine
Dopamine
T3
T4
How are ACTH and melanocyte stimulating hormone (MSH) linked?
Both are portions of POMC. POMC is cleaved into multiple segments including ACTH and MSH. This is why addison's disease is characterized by an abundance of ACTH and hyperpigmentation