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90 Cards in this Set

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acromegaly

rare hormonal disorder in adulthood, usually caused by a GH-secreting pituitary tumor (adenoma) that promotes the soft tissue and bones of the face, hands, and feet to grow larger than normal.


Treatment: surgery involves partial resection of the pituitary gland

diuresis

increased formation and secretion of urine

glycosuria

abnormal amount of glucose in the urine

Graves disease

multisystem autoimmune disorder characterized by pronounced hyperthyroidism usually associated with enlarged thyroid gland (goiter) and exophthalmos (abnormal protusion of the eyeball)

hirsutism

excessive distribution of body hair, especially women


*in women usually caused by abnormalities of androgen production or metabolism

hypercalcemia

condition in which the calcium level in the blood is higher than normal


*overactivity in one or more parathyroid glands

hyperkalemia

condition in which the potassium level in the blood is higher than normal

hypervolemia

abnormal increase in the volume of blood plasma (liquid part of the blood and lymphatic fluid) in the body


*results from retention of large amounts of sodium and water by the kidneys

hyponatremia

lower than normal level of sodium in the blood

insulinoma

tumor of the islets of Langerhans of the pancreas

obesity

excessive accumulation of fat that exceeds the body's skeletal and physical standards, usually an increase of 20 percent or more above ideal body weight

morbid obesity

BMI of 40 or greater, which is generally 100 or more pounds over ideal body weight

panhypopituitarism

total pituitary impairment that brings about a progressive and general loss of hormone activity

pheochromocytoma

small chromaffin cell tumor, usually located in the adrenal medulla, causing elevated heart rate and blood


*may be life threatening

thyroid storm

crisis of uncontrolled hyperthyroidism caused by the release into the bloodstream of an increased amount of thyroid hormone; also called thyroid crisis or thyrotoxic crisis

virilism

masculinization or development of male secondary sex characteristics in a woman

exophthalmometry

measures the degree of forward displacement of the eyeball as seen in Graves disease

parathyroidectomy

excision of one or more of the parathyroid glands, usually to control hyperparathyroidism

transsphenoidal hypophysectomy

endoscopic procedure to surgically remove a pituitary tumor through an incision in the sphenoid sinus (trannsphenoidal) without disturbing brain tissue

thymectomy

excision of the thymus gland

thyroidectomy

excision of the entire thyroid gland, a part of it, (subtotal) or a single lobe (thyroid lobectomy)

fasting blood sugar

test that measures glucose levels in a blood sample following a fast of at least 8 hrs


*helps diagnose diabetes and monitor glucose levels

glucose tolerance test (GTT)

screening test in which a dose of glucose is administered and blood samples are taken afterward at regular intervals to determine how quickly glucose is cleared from the blood


*diagnose pre-diabetes and gestational diabetes

insulin tolerance test (ITT)

diagnostic test in which insulin is injected into the vein to assess pituitary function, adrenal function, and to determine insulin sensitivity

thyroid function test (TFT)

test that detects an increase or decrease in thyroid function

total calcium test

test that measures calcium to detect bone and parathyroid disorders.

CT-computed tomography

imaging technique that rotates an xray emitter around the area to be scanned and measures the intensity of transmitted rays from different angles

MRI-magnetic resonance imaging

noninvasive imaging technique that uses radio waves and a strong magnetic field, rather than an xray beam, to produce multiplanar cross-sectional images

radioactive iodine uptake (RAIU)

administration of a radioactive iodine (RAI) in pill or liquid form is used as a tracer to test how quickly the thyroid gland takes up (uptake) iodine from the blood

thyroid scan

images of the thyroid gland are obtained after oral or intravenous administration of a small dose or radioactive iodine

antidiuretics

reduce or control excretion of urine

antithyroids

treat hyperthyroidism by impeding the formation of T3 and T4 hormones


*administered in thyroidectomy and in thyrotoxic crisis

corticosteroids

replace hormones lost in adrenal insufficiency (Adddison disease)


*used to suppress inflammation, control allergic reactions, reduce rejection in transplantation, and treat some cancers

growth hormone replacements

increase skeletal growth in children and growth hormone deficiencies in adults


*increase spinal bone density and help manage growth failure in children

insulins

lower blood glucose levels by promoting its entrance into body cells and converting glucose to glycogen (a starch form of glucose)

oral antidiabetics

treat type 2 diabetes mellitus by stimulating the pancreas to produce more insulin and decrease peripheral resistance to insulin


*not insulin and are not used in treating type 1 diabetes

thyroid supplements

replace or supplement thyroid hormones


*contains T3, T4, or a combination of both. Used to treat some types of thyroid cancer

ACTH

adrenocorticotropic stimulating hormone

ADH

antidiurectic hormone

DI

diabetes insipidus; diagnostic imaging

DKA

diabetic ketoacidosis

DM

diabetes mellitus

FBS

fasting blood sugar

FSH

follicle stimulating hormone

GH

growth hormone

GTT

glucose tolerance test

HRT

hormone replacement therapy

K

potassium

LH

luteinizing hormone

PRL

prolactin

PGH

pituitary growth hormone

PTH

parathyroid hormone

RAI

radioactive iodine

RAIU

radioactive iodine uptake

T3

triiodothyronine

T4

thyroxine

TFT

thryroid function test

TSH

thyroid stimulating hormone

hyposecretion

underproduction (treated by drug therapy)

hypersecretion

overproduction (treated by surgery)

pituitary disorders

related to hypo/hypersecretion of GH which leads to body size abnormalities


*abnormal ADH difficult for body to remove water

hyponatremia

low blood sodium levels



ADH test

used to diagnose diabetes insipidus or the syndrome of inappropriate antidiuretic hormone (SIADH)

thyroid disorders

common, can occur at any time in life


Cretinism


Graves disease


myxedema


exophthalmos

cretinism

hypothyroidism develops in children, can lead to mental retardation, impaired growth, low body temps, and abnormal bone formation

myxedema

hypothyroidism developed in adulthood


*edema, low blood levels of T3 and T4, weight gain, cold intolerance, fatigue, depression, muscle or joint pain and sluggishness

tetany

decreased calcium causes muscle twitches and spasms

osteitis fibrosa cystica

demineralization of bones due to the increase in pTH secretion

osteoporosis

porous bones highly susceptible to fracture and deformity

adenoma

benign glandular tumor of the parathyroid

von Recklinghausen disease

excess PTH causes calcium deposits in the kidneys, when this is generalized and all bones are affected

nephrolithiasis

renal symptoms and kidney stones

adrenal cortex

associated with Addison disease and Cushing syndrome

Addison disease

relatively uncommon chronic disorder caused by deficiency of cortical hormones. Results when adrenal cortex is damaged or atrophied


chronic dehydration, anorexia, muscle weakness, fatigue, gastrointestinal symptoms, hypotension

Cushing disease

cluster of symptoms produced by excessive amounts of cortisol, adrenocorticotropic hormone, or both circulating in the blood


*Steroid use


*adrenal tumor


*alters carbs and protein metabolism and electrolyte balance

adrenal medulla

no specific diseases can be traced directly to a deficiency of hormones.


medullary tumors can cause excess secretions


*most common disorder is neoplasm pheochromocytoma excessive amounts of epinephrine and norepinephrine

pancreatic disorders

diabetes is most common

diabetes

chronic metabolic disorder of impaired carbs, protein, and fat metabolism due to insufficient production of insulin or the body's inability to use insulin properly

ketosis

when fat metabolism produces ketones that enter the blood

glucosuria

when blood glucose levels elevate beyond a level tolerated by the kidneys, glucose spills into the urine and expelled from the body along with electrolytes

CAUTION (Type 1)

Constant urination


Abnormal thirst


Unusual hunger (polyphagia)


The rapid loss of weight


Irritability


Obvious weakness and fatigue


Nausea and vomiting

Diabetes (type 2)

Drowsiness


Itching


A family history of diabetes


Blurred vision


Excessive weight


Tingling, numbness, and pain in the extremities


Easily fatigued


Skin infections and slow healing of cuts and scratches, especially of the feet

polyphagia

hunger and increased appetite

Type 1 diabetes

usually kids and young adults


*body doesn't produce sufficient insulin


*balance diet, exercise, and insulin daily injections


*monitors blood glucose levels several times a day

Type 2 diabetes

*most common form


*Onset is typically later in life


*body is deficient in producing sufficient insulin or the body's cells are resistant to insulin action in target tissues


*hyperglycemia may result in damage of kidneys, eyes, nerves, or heart

complications type 1

report high rapidly developing symptoms


DKA-diabetic ketoacidosis over several days or weeks

complications type 2

symptoms are commonly vague, long standing, and develop gradually

gestational diabetes

may occur in women who are not diabetic, but develop diabetes during pregnancy

pancreatic cancer

most arise in epithelial tumors


presence known by obstruction and local invasion


*prognosis is poor with 2% survival rate in 5 years

thyroid carcinoma

cancer of the thyroid gland


*predisposing factors of radiation, prolonged TSH stimulation, familial disposition, and chronic goiter