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7 Cards in this Set
- Front
- Back
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Hyperfunctioning thyroid nodules often have what "stuck" in the on position?
Commonest thyroid cancer, multifocal: What triples your risk of differentiated thyroid cancer? Most often mutated gene: |
TSH receptor
papillary carcinoma Hashimoto's serine-threonine kinase BRAF |
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Name for nuclei with heterochromatin pushed to edges, central area clear:
Explain "Orphan Annie's tumor": How does papillary carcinoma usually kill people? |
"Orphan Annie" nuclei
papillary - younger women stays around for years well-behaved, seldom kills "Orphan Annie's eye" psammoma bodies ("Sandy") asphyxiation |
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Cribiform-morulant variant of papillary carcinoma usually means what?
More aggressive tumor, characterized by vascular invasion and spread: Differences in appearance between papillary and follicular: |
pt likely has familial polyposis coli
follicular carcinoma follicular has no Orphan Annie eye bodies, psammoma bodies, papillae takes up radioactive iodine |
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follicular carcinoma usually mets where?
C-cell cancer, usually with MEN II, produces calcitonin: What is the MEN II gene? Uncommon B-cell neoplasm arising usually in Hashimoto's: |
lungs, bone
medullary carcinoma RET primary thyroid lymphoma |
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Why is the thymus a good location for an ectopic parathyroid gland?
What is in myoid cells of the thymus? Common in folks with autoimmune diseases, early HIV: What occurs in about 50% of thymoma patients? |
arises from 3rd/4th pharyngeal pouches
actin, myosin, myoglobin thymic follicular hyperplasia myasthenia gravis |
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Hypogammaglobulinemia with thymoma:
5 T's of anterior mediastinal masses: |
Good's syndrome
Thymoma Teratoma Testicular-type T-cell or Hodgkin's Thyroid enlargement |
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What happens in kids with pineal tumors?
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seuxal precocity
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