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3 Cards in this Set

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  • Back
What are the three major cell types of the Islets of Langerhans, and what are their functions?
1. alpha (A) cells - 15-20% of islet cells - located peripherally in islet - secrete glucagon
2. beta (B) cells - 70% of islet cells - located centrally in islet - secrete insulin
3. delta (D) cells - 5-10% of islet cells - located peripherally in islet - secrete somatostatin
What are the minor cell types (~5%) of the Islets of Langerhans, and what are their functions?
PP cells (F cells) produce pancreatic polypeptide
D-1 cells produce vasoactive intestinal peptide
EC cells produce secretin, motilin and substance P
What hormones does the pancreas produce?
-Insulin
-Glucagon
-Somatostatin