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46 Cards in this Set

  • Front
  • Back
S/S of hypothyroidism
-thin brittle fingernails
-pale
-decreased ability to sweat
-retain water
-bradycardia
-dry puffy skin
-hoarseness
-constipation
-increased menstraul flow & more frequent menses
-problems w/ infertility & miscarriage
S/S of hyperthroidism
-heat intolerance
-tachycardia
-weight loss
-agitation
-nervousness
-lighter menses
-fine brittle hair
-shaky hands
-panic disorder
-insomnia
-thin skin
-sweat a lot
-very irritable
Myxedema
-hypothryoidism
Cretinism
-hypothyroidism
Grave's disease
-hyperthyroidism
Toxic nodular goiter
-hyperthyroidism
Levothroid, Levoxyl, Synthroid, & Unithroid
-treats hypothyroidism (Levothyroxine T4)
-not interchangeable bc of fillers
-cannot miss a dose
-lifetime drug
Cytomel & Triostat
-Liothyronine ((T3)
Methimazole (Tapazole)
-PTU (Propylthiouracil)
-treats hyperthyroidism
-blocks thyroid hormone synthesis by preventing the utilization of iodine
Ridioactive Iodine (131 I)
-treats hyperthyroidism
-destroys the thyroid gland
-low cost & permanent
-causes hypothyroidism which is easier to treat
Lugol's Solution
-treats hyperthyroidism
-Nonradioactive Iodine
-decreases thyroid production
-has K & iodine
Many antithyroid meds (PTU) are...
-contracindicated in pregnancy (can cross placenta & into breastmilk)
Somatropin (Humatrope)
-treats too little GH
-IM & SQ (SQ preferred)
Somatrem (Protropin)
-treats too little GH
-IM & SQ (SQ preferred)
Octreotide (Sandostatin)
-treats too much GH
-SQ w/ indefinite treatment
Pegvisomant (Somavert)
-treats too much GH
-SQ w/ indefinite treatment
Vasopressin (Pitressin)
-treats too little ADH (emergency situations)
-IM or SQ
-causes vasoconstriction & is more potent
Desmopressin (DDAVP)
-treats too little ADH (preferred)
-intranasal, IV, SQ, & PO
When taking meds to treat too little ADH pts must...
-decrease water intake (or water intoxication & brain swelling will occur)
Too little adrenocortical hormone will result in...
-addison's disease
-acute adrenal insufficiency
-congenital adrenal hyperplasia
Too little ADH will cause...
-diabetes insipidus
-polydipsia
-polyuria (high urine output but very diluted)
Too much GH in adults causes...
-acromegaly (bones in face & joint continue to grow)
Too much GH in children will cause...
-gigantism (usually turns to acromegaly as adults)
Too little GH in children will cause...
-short stature (stop treatment when they are done growing <growth plate closure>)
Too little GH in adults will cause
-decreased muscle mass
-increased cardiovascular mortality
Too little adrenocortical hormone therapy will last how long?
for life
Hydrocortisone
-preferred replacement med for too little adrenocortical hormone
-IV (acute)
-PO (chronic)
Dexamethasone
-replacement med for too little adrenocortical hormone
-helps w/ diagnosis of adrenal dysfunction
Fludrocortison (Florinef)
-replacement med for too little adrenocortical hormone
-used a lot for Addison's disease
Chronic glucocorticoid use will cause...
-Cushings sydrome (moon face <round, flat appearance>)
Glucocorticoids are used to treat...
-too much adrenocortical hormone
-Cushing's syndrome (treat cause)
Mineralocorticoids treat __ but cause ___
-treat primary hyperaldosteronism
-cause HTN
Ketoconazole (Nizoral)
-antifungal that treats ringworm but also decreases glucocorticoid synthesis (no longer produce as much)
-treats too much hormone (adrenocortical, etc)
Aminoglutethimide (Cytadren)
-treats too much hormone (adrenocortical, etc)
-blocks conversion in steroid synthesis (not able to be utilized)
Testosterone (androgen) uses
-male hypogonadism
-delayed puberty
-breast cancer in women (not men bc it will feed it)
-menopausal women
-wasting syndrome w/ AIDS pts (increases appetite)
Adverse effects of androgen use (or athletic abuse)
-HTN (hold on to Na & H2O)
-testicular shrinkage
-acne
-increased LDL
-hepatoxicity
-depression & aggression
-roid rage
Silendafil (Viagra)
-treats erectile dysfunction
-PDE5 Inhibitor
-Wait 24-48 hours after taking
-fever, headache, flushing, diarrhea, dizziness, nasal congestion
Vardenafil (Levitra)
-treats erectile dysfunction
-PDE5 Inhibitor
-Wait 24-48 hours after taking
-fever, headache, flushing, diarrhea, dizziness, nasal congestion
Tadafil (Cialis)
-treats erectile dysfunction
-PDE5 Inhibitor
-must wait 48-72hrs before taking nitrates
fever, headache, flushing, diarrhea, dizziness, nasal congestion
PDE5 Inhibitors cannot be taken w/...
-nitrates b/c they will cause profound hypotension
Most common causes of erectile dysfunction
-HTN & coronary artery disease
Alprostadil
-given by injection or pellet
into the penis
-used when severe HTN meds must be given
Tamsulosin (Flomax) & Alfuzosin (Uroxatral)
-category X
-ONLY for BPH treatment
-Alpha1 adrenergic blockers
Terazosin (Hytrin) & Doxazosin (Cardura)
-BPH & HTN treatment
-Alpha1 adrenergic blockers
Finasteride (Proscar)
-BPH treatment
-5-alpha-reductase-inhibitors
-promotes regression of prostatic tissue so mechanical obstruction decreases (urethra opens)
-results in 6-12 months
Dutasteride (Avodart)
-5-alpha-reductase-inhibitors
-promotes regression of prostatic tissue so mechanical obstruction decreases (urethra opens)
-results in 6-12 months