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46 Cards in this Set
- Front
- Back
S/S of hypothyroidism
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-thin brittle fingernails
-pale -decreased ability to sweat -retain water -bradycardia -dry puffy skin -hoarseness -constipation -increased menstraul flow & more frequent menses -problems w/ infertility & miscarriage |
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S/S of hyperthroidism
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-heat intolerance
-tachycardia -weight loss -agitation -nervousness -lighter menses -fine brittle hair -shaky hands -panic disorder -insomnia -thin skin -sweat a lot -very irritable |
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Myxedema
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-hypothryoidism
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Cretinism
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-hypothyroidism
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Grave's disease
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-hyperthyroidism
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Toxic nodular goiter
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-hyperthyroidism
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Levothroid, Levoxyl, Synthroid, & Unithroid
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-treats hypothyroidism (Levothyroxine T4)
-not interchangeable bc of fillers -cannot miss a dose -lifetime drug |
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Cytomel & Triostat
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-Liothyronine ((T3)
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Methimazole (Tapazole)
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-PTU (Propylthiouracil)
-treats hyperthyroidism -blocks thyroid hormone synthesis by preventing the utilization of iodine |
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Ridioactive Iodine (131 I)
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-treats hyperthyroidism
-destroys the thyroid gland -low cost & permanent -causes hypothyroidism which is easier to treat |
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Lugol's Solution
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-treats hyperthyroidism
-Nonradioactive Iodine -decreases thyroid production -has K & iodine |
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Many antithyroid meds (PTU) are...
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-contracindicated in pregnancy (can cross placenta & into breastmilk)
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Somatropin (Humatrope)
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-treats too little GH
-IM & SQ (SQ preferred) |
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Somatrem (Protropin)
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-treats too little GH
-IM & SQ (SQ preferred) |
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Octreotide (Sandostatin)
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-treats too much GH
-SQ w/ indefinite treatment |
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Pegvisomant (Somavert)
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-treats too much GH
-SQ w/ indefinite treatment |
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Vasopressin (Pitressin)
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-treats too little ADH (emergency situations)
-IM or SQ -causes vasoconstriction & is more potent |
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Desmopressin (DDAVP)
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-treats too little ADH (preferred)
-intranasal, IV, SQ, & PO |
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When taking meds to treat too little ADH pts must...
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-decrease water intake (or water intoxication & brain swelling will occur)
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Too little adrenocortical hormone will result in...
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-addison's disease
-acute adrenal insufficiency -congenital adrenal hyperplasia |
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Too little ADH will cause...
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-diabetes insipidus
-polydipsia -polyuria (high urine output but very diluted) |
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Too much GH in adults causes...
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-acromegaly (bones in face & joint continue to grow)
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Too much GH in children will cause...
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-gigantism (usually turns to acromegaly as adults)
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Too little GH in children will cause...
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-short stature (stop treatment when they are done growing <growth plate closure>)
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Too little GH in adults will cause
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-decreased muscle mass
-increased cardiovascular mortality |
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Too little adrenocortical hormone therapy will last how long?
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for life
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Hydrocortisone
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-preferred replacement med for too little adrenocortical hormone
-IV (acute) -PO (chronic) |
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Dexamethasone
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-replacement med for too little adrenocortical hormone
-helps w/ diagnosis of adrenal dysfunction |
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Fludrocortison (Florinef)
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-replacement med for too little adrenocortical hormone
-used a lot for Addison's disease |
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Chronic glucocorticoid use will cause...
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-Cushings sydrome (moon face <round, flat appearance>)
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Glucocorticoids are used to treat...
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-too much adrenocortical hormone
-Cushing's syndrome (treat cause) |
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Mineralocorticoids treat __ but cause ___
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-treat primary hyperaldosteronism
-cause HTN |
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Ketoconazole (Nizoral)
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-antifungal that treats ringworm but also decreases glucocorticoid synthesis (no longer produce as much)
-treats too much hormone (adrenocortical, etc) |
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Aminoglutethimide (Cytadren)
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-treats too much hormone (adrenocortical, etc)
-blocks conversion in steroid synthesis (not able to be utilized) |
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Testosterone (androgen) uses
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-male hypogonadism
-delayed puberty -breast cancer in women (not men bc it will feed it) -menopausal women -wasting syndrome w/ AIDS pts (increases appetite) |
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Adverse effects of androgen use (or athletic abuse)
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-HTN (hold on to Na & H2O)
-testicular shrinkage -acne -increased LDL -hepatoxicity -depression & aggression -roid rage |
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Silendafil (Viagra)
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-treats erectile dysfunction
-PDE5 Inhibitor -Wait 24-48 hours after taking -fever, headache, flushing, diarrhea, dizziness, nasal congestion |
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Vardenafil (Levitra)
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-treats erectile dysfunction
-PDE5 Inhibitor -Wait 24-48 hours after taking -fever, headache, flushing, diarrhea, dizziness, nasal congestion |
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Tadafil (Cialis)
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-treats erectile dysfunction
-PDE5 Inhibitor -must wait 48-72hrs before taking nitrates fever, headache, flushing, diarrhea, dizziness, nasal congestion |
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PDE5 Inhibitors cannot be taken w/...
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-nitrates b/c they will cause profound hypotension
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Most common causes of erectile dysfunction
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-HTN & coronary artery disease
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Alprostadil
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-given by injection or pellet
into the penis -used when severe HTN meds must be given |
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Tamsulosin (Flomax) & Alfuzosin (Uroxatral)
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-category X
-ONLY for BPH treatment -Alpha1 adrenergic blockers |
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Terazosin (Hytrin) & Doxazosin (Cardura)
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-BPH & HTN treatment
-Alpha1 adrenergic blockers |
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Finasteride (Proscar)
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-BPH treatment
-5-alpha-reductase-inhibitors -promotes regression of prostatic tissue so mechanical obstruction decreases (urethra opens) -results in 6-12 months |
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Dutasteride (Avodart)
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-5-alpha-reductase-inhibitors
-promotes regression of prostatic tissue so mechanical obstruction decreases (urethra opens) -results in 6-12 months |