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35 Cards in this Set

  • Front
  • Back
What drug might be used to treat mineralocorticoid insufficiency?
Fludrocortisone
What drug might be used to block cortisol receptors?
mifepristone
What drug is a glucocorticoid receptor antagonist?
Mifepristone
What drug might be used to reduce plasma ACTH?
Dexamethasone
What drug might be used to block cortisol synthesis?
Ketoconazole
Metyrapone
Trilostane
What drug might be used to treat hypocortisolism?
Cortisol
What thyroid drug can cause agranulocytosis?
PTU
Methimazole
"thionamides"
What thyroid drug can cause an allergic reaction?
PTU
Methimazole
"thionamides"
What are the s/e of levothyroxine?
increased heart activity
What is the Wolff-Chalkoff effect?
high doses of iodide can inhibit iodide organification to prevent excess thyroxine production
What thionamide is preferred during pregnancy?
PTU
What are the inhibitors of iodine transport?
thiocyanate
perchlorate
What is the major s/e of iodine?
angioedema
fever
(allergy rxn)
What effect does dopamine have on TSH?
decreases it
What non-insulin agents for DM stimulate insulin release in the setting of glucose?
"Meglitinides"
Repaglinide
Nateglinide
What drug for DM enhances insulin sensitivity in the liver & periphery?
Metformin
What drug delays absorption of complex carbs?
alpha-glucosidase inhibitors
What drug increases insulin senstivity in muscle & fat?
Thiazolideinediones (DPP-4 ihibitiros)
What DM drug can cause lactic acidosis?
Metformin
What DM drugs cause weight gain?
Sulfonylureas
Meglitinides
Thiazolidendiones
What DM drug decreases the effectiveness of oral contraceptives?
Thiazolidediones
What DM drug has renal concerns?
Metformin
What DM drug has to be used carefully w/liver dz?
meglitinides
What DM drug causes volume expansion w/large weight gain?
Thiazolidediones (DPP-4 inhibitors)
What drug do you NOT use if the patient does not have DM?
Thiazoldiediones
What are the traditional bolus insulins?
Regular bolus insulin
What are the traditional basal insulins?
NPH/lente
Ultralente
What are the newer bolus insulins?
Lispro/aspart/glulisine
What are the newer basal insulins?
glargine, detemir
What are the glucose goals for T1DM?
Pre-prandial 90-130
Post-prandial <180
What do GLP-1 & GIP do?
Enhance glucose uptake by the muscle
List the neuroglycopenic symptoms of hypoglycemia.
fatigue
dizziness
headache
vision changes
confusion
seizures
loss of consciousness
List the autnomic/sympathoadrneal symptoms of hypoglycemia.
Sweating
hunger
nausea
anxiety
palpitations
tremor
pallor
flushing
What drug hyperpolarizes the beta cells?
Diazoxide
Give the equation of DBW.
Men: 106lbs for 1st 5' then 6lbs for each inch over
Women: 100lbs for 1st 5' then 5' for each inch over