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35 Cards in this Set
- Front
- Back
What drug might be used to treat mineralocorticoid insufficiency?
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Fludrocortisone
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What drug might be used to block cortisol receptors?
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mifepristone
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What drug is a glucocorticoid receptor antagonist?
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Mifepristone
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What drug might be used to reduce plasma ACTH?
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Dexamethasone
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What drug might be used to block cortisol synthesis?
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Ketoconazole
Metyrapone Trilostane |
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What drug might be used to treat hypocortisolism?
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Cortisol
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What thyroid drug can cause agranulocytosis?
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PTU
Methimazole "thionamides" |
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What thyroid drug can cause an allergic reaction?
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PTU
Methimazole "thionamides" |
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What are the s/e of levothyroxine?
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increased heart activity
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What is the Wolff-Chalkoff effect?
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high doses of iodide can inhibit iodide organification to prevent excess thyroxine production
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What thionamide is preferred during pregnancy?
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PTU
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What are the inhibitors of iodine transport?
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thiocyanate
perchlorate |
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What is the major s/e of iodine?
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angioedema
fever (allergy rxn) |
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What effect does dopamine have on TSH?
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decreases it
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What non-insulin agents for DM stimulate insulin release in the setting of glucose?
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"Meglitinides"
Repaglinide Nateglinide |
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What drug for DM enhances insulin sensitivity in the liver & periphery?
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Metformin
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What drug delays absorption of complex carbs?
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alpha-glucosidase inhibitors
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What drug increases insulin senstivity in muscle & fat?
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Thiazolideinediones (DPP-4 ihibitiros)
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What DM drug can cause lactic acidosis?
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Metformin
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What DM drugs cause weight gain?
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Sulfonylureas
Meglitinides Thiazolidendiones |
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What DM drug decreases the effectiveness of oral contraceptives?
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Thiazolidediones
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What DM drug has renal concerns?
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Metformin
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What DM drug has to be used carefully w/liver dz?
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meglitinides
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What DM drug causes volume expansion w/large weight gain?
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Thiazolidediones (DPP-4 inhibitors)
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What drug do you NOT use if the patient does not have DM?
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Thiazoldiediones
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What are the traditional bolus insulins?
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Regular bolus insulin
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What are the traditional basal insulins?
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NPH/lente
Ultralente |
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What are the newer bolus insulins?
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Lispro/aspart/glulisine
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What are the newer basal insulins?
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glargine, detemir
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What are the glucose goals for T1DM?
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Pre-prandial 90-130
Post-prandial <180 |
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What do GLP-1 & GIP do?
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Enhance glucose uptake by the muscle
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List the neuroglycopenic symptoms of hypoglycemia.
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fatigue
dizziness headache vision changes confusion seizures loss of consciousness |
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List the autnomic/sympathoadrneal symptoms of hypoglycemia.
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Sweating
hunger nausea anxiety palpitations tremor pallor flushing |
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What drug hyperpolarizes the beta cells?
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Diazoxide
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Give the equation of DBW.
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Men: 106lbs for 1st 5' then 6lbs for each inch over
Women: 100lbs for 1st 5' then 5' for each inch over |