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75 Cards in this Set

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HYPOTHALAMIC RELEASING HORMONES

GHRH


TRH


GnRH


CRH


PRH


SOMASTATIN


PIF


What releasing-hormone is used to diagnose Cushings Disease and treat peritumoral brain edema

CRH

Puberty before age 12

Precocious puberty

Used to treat endometriosis snd precocious puberty

Leuprolide

Used to treat hypogonadism is males, prepubetal cryptorchodism, and induce ovulation in females

Chorionic Gonadotropin

Hormone responsible for linear skeletal growth, internal organs, and protein synthesis

Growth hormone

A result if there is a abnormality, tumors, circulatory disturbances, inflammation the pituitary gland

Hypopituitarism

A GH deficiency leading to short stature

Dwarfism

A result of pituitary tumors or trauma

Somatropin deficiency Syndrome

A result of pituitary tumors or trauma

Somatropin deficiency Syndrome

A 20 yr old asks the SN if he can take growth hormones bc he wants to be taller, what would you respond

No bc ur epiphyseal plates have closed

What occurs when there is hypersecretion of GH

Hyperpituitarism

Classificayion of Drug given for those with hyperpituatarism

Growth hormone antagonists

Hypersecretion of GH before puberty

Gigantism

Hypersecretion of GH after puberty

Acromegaly

Is SOMASTATIN inhibitory or excitatory?


Inhibitory aka GHIH

More potent in inhibiting GH but DOES NOT AFFECT INSULIN RELEASE

Octreotide acetate

Used to treat acromegaly HOWEVER CAN BLOCK LACTATION

Bromocriptine

Posterior Pituitary Hormones

ADH

Occurs when there is insufficient secretion of ADH which keads to large urine amount with no glucose

Diabetic Insipidus

Drugs given to Diabetic Insipidus

Vasopressin and Desmoressin

Action of ADH drugs

Release ADH to increase plasma osmolarity

Classification of Drugs nthat supresses immune system

Adrenocortical Agents

Adrenocortical Agents include:

Glucocorticoids and Mineralocorticoids

Flattemed bodies on top of kidneys that produce androgen, glucocorticoids, mineralocorticoids,

Adrenal Glands

Flattemed bodies on top of kidneys that produce androgen, glucocorticoids, mineralocorticoids,

Adrenal Glands

Occurs when adrenal gland is damaged and cannot produce enough hormones



Or


Fr prolonged use of corticosteroids

Adrenal Insufficiency

Px unable to supplement the energy consuming effects of sympathetic rxn



CANNOT RESPOND TO STRESS

Adrenal crisis

Corticosteroid that blocks inflammation in respi tract

Beclamethasone (Beclovent)

DOC for Crohn's Disease

Budesonide

Drug for Acne Vulgaris

Dexamethason

DOC for inflammatoru and immuse disorders

Methylprednisone

Since steroids, adverse rxn would be

Weight gain and increase appetite

Increases sodium resorption in ren tubules and increase K and H excretion

Mineralocorticoids

Syndrome in which body cannot absorb Na

Saltwasting Adrenogenital Syndrome

Mineralcorticoid for severe orthodtatic hypotension

Fludrocortisone (Florinef)

T4

Tetraiodothyronine



Levothyroxine

T3

Triiodothyronine



Iothyronine

Reduces calcium levels by bloclimg bone resorption and enhancing bone formation


Calcitonin


Causes of hypothyroidism


Lack of thyroid gland


Lack of sufficient iodine in diet


Lack of thyroid tissue


Lack of TSH and TRH

When children is born without a thyroid gland or a nonfunctional one

Cretinism

When children is born without a thyroid gland or a nonfunctional one

Cretinism

Severe form of Hypothyroidism

myxedema

Severe form of Hyperthyroidism

Graves Disease

Most frequently used symthetic T4

Levothyroxine ( Synthroid)

Synthetic T3 and has high cardiac side effects

Liothyronine

Prevents formation of thyroid hormone in thyroid cells

Thioamides

Causes thyroid cells ro bebsayurqted with uodine thus stopping production of thyroid hormone

Iodine solution

Metallic taste and burning in mouth, sore throat, gums, stomach upset

Iodism

Increases calcium in body

Parathyroid Hormone

What mobilizes calcium and inhibits release of PTH

Magnesium

Most likely happens if parathyroid gland in removed

Hypoparathyroidism

Treatment of hypoparathyroidism

Calcium and vit. D therapy

Treatment of hypoparathyroidism

Calcium and vit. D therapy

DOC for osteoporosis in men

Alendronate

Where can you derive calcitonin from other sources

Human and salmon

Alpha cells release

Glucagon

Beta cells release

Insulin

Beta cells release

Insulin

Delta cells release

Somastatin

Complication of DM in the lungs

Kussmaul's Respiration

The formation and storage of glycogen in the liver

Glycogenesis

Formation of glucose in the liver

Glucogeonesis

Breakdown of glycogen in the body

Glycogenolysis

Somogyi

Normal


Low


High


Somogyi

Normal


Low


High


Dawn


Normal normal high

Waning insulin


Normal high higher

What not to mix with other insulin

LANTUS OR LEVEMIR

Oral antidiabetic


Biguanide



Meglitinides



Alpha Glucose Inhibitors



Sulfonylureas



Thiazolidenediones

Combination of Metaglip

Metformin + Glyburide

Glipizide + Metformin

Metaglip

Gyburide + Metformin

Glucovance

Sugar level after eatinf

Postprandial Glucise

New DA that makes satiety

Symlin