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17 Cards in this Set

  • Front
  • Back
GH and prolactin are acidophilic or basohilic cells?
acidophilic
ACTH, POMC, MSH, TSH, FSH, LH are acidophilic or basohilic cells?
basohilic
posterior pituitary produces what?
Anti-diuretic hormone (ADH)
Oxytocin

(posterior stops your pee! posterior, post sex, cuddle...if your a biddie)
NEUROHYPOPHYSIS=

ADENOHYPOPHYSIS=
NEUROHYPOPHYSIS= Posterior

ADENOHYPOPHYSIS= Anterior

pituitary
if you see an excess of production of the anterior pituitary hormones you might start thinking there is what problem in the brain?
adenoma in the anterior lobe of the pituitary

note: if the levels aren't SKY HIGH then it probably is NOT adenoma
30% of all adenomas are what? (most common functional pituitary tumor)
Prolactinoma
pt presents with amenorrhea, infertility, loss of libido & galactorrhea...what problem do they likely have?
Prolactinoma

30% of all adenomas are prolactinomas (most common functional pituitary tumor)
what is the difference btw gigantism and acromegaly?
increase in GH before closure of epiphyses-->gigantism (starts as kid)

increase in GH after closure of epiphyses --> acromegaly (happens to adults)
Cushing's syndrome due to an anterior pituitary adenoma is due to an increased production in?
ACTH
middle aged men & women
produce neurologic symptoms – impaired vision, cephalgia, diplopia
gonadotrophadenomas – LH & FSH producing
this is found in the anterior pituitary and can be seen histologically but Rarely have a significant hormonal output that leads to clinical dz...
MICROADENOMA
this lesion is described as having a "machine oil" appearance, and is derived from remnants of Rathke's pouch.
CRANIOPHARYNGIOMA

(benign tumor)

from Wiki: Craniopharyngioma is a rare, usually suprasellar neoplasm, which may be cystic, that develops from rests of epithelium derived from Rathke's pouch.Rathke's pouch is an embryonic precursor of the anterior pituitary.
Ischemic necrosis and Sheehan syndrome...what does this lead to?
anterior pituitary can tolerate ischemia reasonably well (>75% damage --> hypopituitarism)
post-partum necrosis of anterior pituitary – most common form of clinically significant ischemic necrosis of the anterior pituitary describes....?

this can be a result of what?

***
Sheehan syndrome

result of obstetric hemorrhage or shock
may be 2° to other causes - - DIC & rarely sickle cell disease, increased intracranial pressure, traumatic injury, shock
stimulates contraction of smooth muscle cells in gravid uterus & those that surround the lactiferous ducts in mammary glands
oxytocin
diabetes insipidus (deficiency)
inappropriately high levels of ADH

can be a result of what?
posterior pituitary lesions! (these both involve ADH)
Hypopituitarism secondary to lack of releasing hormones
Central diabetes insipidus due to lack of ADH synthesis
Precocious puberty due to mid line hamartoma in boys

all may be due to?
Hypothalamic disorders