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17 Cards in this Set

  • Front
  • Back
AE: Methotrexate (5)
GI upset
myelosuppression
hepatic fibrosis
cirrhosis
pulmonary infiltrates/fibrosis
AE: Leflunomide (4)
diarrhea
rash
headache
reversible alopecia
AE: Hydroxychloroquine (3)
nausea
diarrhea
visual changes (night blindness)
AE: Sulfasalazine (4)
myelosuppression
alopecia
GI upset
rash
AE: Etanercept (3)
injection site reactions
infections
malignancies
AE: Infliximab
hypersensitivity: fevers, chills, urticaria
AE: Adalimumab (3)
infections
malignancies
local injection site reactions
AE: Anakinra (3)
local injection site reactions
infections
neutropenia
AE: Abatacept (9)
headache
dizziness
cough
back pain
hypertension
dyspesia
UTI
rash
extremity pain
CI: Methotrexate (9)
pregnancy
nursing
chronic liver disease
immunodeficiency
pleural or peritoneal effusions
leukopenia
thrombocytopenia
blood disorders
creatinine clearance of less than 40 ml/min
+ Methotrexate (2)
DC if AST/ALT >2x ULN

folic acid supplementation to prevent deficiency
CI: Leflunomide (2)
teratogenic (wait 3 months, or give cholestyramine to speed up)

pre-existing liver disease
+ Leflunomide
Efficacy similar to MTX, but more $$
+ Hydroxychloroquine
Less efficacy, but better AE
+ Sulfasalazine (2)
absorption decreased with antibiotics

binds to iron supplements
CI: Etanercept (2)
CHF (relative)

sepsis (relative)
CI: Infliximab
CHF (relative)