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17 Cards in this Set
- Front
- Back
AE: Methotrexate (5)
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GI upset
myelosuppression hepatic fibrosis cirrhosis pulmonary infiltrates/fibrosis |
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AE: Leflunomide (4)
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diarrhea
rash headache reversible alopecia |
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AE: Hydroxychloroquine (3)
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nausea
diarrhea visual changes (night blindness) |
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AE: Sulfasalazine (4)
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myelosuppression
alopecia GI upset rash |
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AE: Etanercept (3)
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injection site reactions
infections malignancies |
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AE: Infliximab
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hypersensitivity: fevers, chills, urticaria
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AE: Adalimumab (3)
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infections
malignancies local injection site reactions |
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AE: Anakinra (3)
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local injection site reactions
infections neutropenia |
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AE: Abatacept (9)
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headache
dizziness cough back pain hypertension dyspesia UTI rash extremity pain |
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CI: Methotrexate (9)
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pregnancy
nursing chronic liver disease immunodeficiency pleural or peritoneal effusions leukopenia thrombocytopenia blood disorders creatinine clearance of less than 40 ml/min |
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+ Methotrexate (2)
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DC if AST/ALT >2x ULN
folic acid supplementation to prevent deficiency |
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CI: Leflunomide (2)
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teratogenic (wait 3 months, or give cholestyramine to speed up)
pre-existing liver disease |
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+ Leflunomide
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Efficacy similar to MTX, but more $$
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+ Hydroxychloroquine
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Less efficacy, but better AE
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+ Sulfasalazine (2)
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absorption decreased with antibiotics
binds to iron supplements |
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CI: Etanercept (2)
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CHF (relative)
sepsis (relative) |
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CI: Infliximab
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CHF (relative)
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