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5 Cards in this Set

  • Front
  • Back
what causes bone resorption
incr IL-1
incr IL-6
incr TNF
incr RankL
what decr bone formation
decr IGF-1
what causes bone loss in estrogen deficiency
DIRECT:
*Incr Bone Resorption:
~incr IL-1
~incr IL-6
~incr TNF
~incr RankL

*Decr Bone Formation:
~decr IGF1

INDIRECT:
~Kidney: incr Ca++ excretion
-GI: decr Ca++ abs
-incr PTH (==>bone resorption)
what causes bone loss in aging
DIRECT:
*Incr Bone Resorption:
~incr IL-1
~incr IL-6
~incr TNF
~incr RankL

*Decr Bone Formation:
~decr IGF1

INDIRECT:
~Kidney: incr Ca++ excretion
-GI: decr Ca++ abs
-incr PTH (==>bone resorption)
what causes bone loss in xs glucorticoids
DIRECT:
*Incr Bone Resorption:
~incr IL-1
~incr IL-6
~incr TNF
~incr RankL

*Decr Bone Formation:
~decr IGF1

INDIRECT:
~Kidney: incr Ca++ excretion
-GI: decr Ca++ abs
-incr PTH (==>bone resorption)