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32 Cards in this Set

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The menstrual cycle is the period during which the

oocyte matures,

is ovulated,

enters the uterine tube.
The hormones FSH, LH, estrogen and progesterone produce cyclic changes in the
endometrium
endometrium changes occur due to what Hormones =
4ct
FSH,
LH,
estrogen
progesterone
monthly changes in the internal layer of the uterus constitute the endometrial cycle, commonly referred to as the
menstrual cycle.
Phases of the Menstrual Cycle

h+
▪Proliferative Phase
▪Luteal/secretory Phase
▪Menstrual Phase
P
L
M
The proliferative (aka) phase
(follicular, estrogenic)

lasting about =
9 days
During the cycle
There is a two- to three-fold increase in the thickness of the
Endometrium
During each cycle, FSH promotes growth of several premordial follicles into
5 to 12 primary follicles.

Hence, 4 to 11 follicles degenerate each month.
fluid-filled spaces appear around the follicular cells, which coalesce to form a single large cavity-
antrum, which contains follicular fluid.

After the antrum forms, the ovarian follicle is called a =
vesicular or secondary follicle
The primary oocyte is pushed to one side of the follicle, where it is surrounded by a mound of follicular cells, the =
cumulus oophorus, that projects into the antrum
Hormones produced by the ovary:
estrogen
androgens
***Theca interna produce
H =
2ct
Estrogen & Androgen
Hormones produced by the ovary:
Growing follicles produce
estrogen
Hormones produced by the ovary:
The vascular theca interna produces
androgens
and some
estrogen
Hormones produced by the ovary:
stromal secretory cells, known collectively as the interstitial glands of the ovary also produce some
=
estrogen
Primary oocyte completes first meiotic cell division where in the menses =
shortly
before ovulation
Ovulation : Release of
secondary Oocyte.
Ovulation
Occurs around midcycle (14th day

ovarian follicle - under the influence of FSH and LH undergoes a sudden growth spurt producing a cystic swelling or bulge on the surface of the ovary

A small avascular spot, =
stigma
soon appears on this swelling

Ovulation is triggered by a surge of =

Ovulation usually follows the LH peak by =

The stigma soon =
LH production

12 to 24 hours

ruptures, expelling secondary oocyte
w/
follicular fluid
***The expelled secondary oocyte is surrounded by the =
zona pellucida

and one or more layers of
follicular cells, which are =
***
arranged as the corona radiata
The zona pellucida is composed of three glycoproteins =
(ZPA, ZPB, ZPC),
which form a network of filaments with multiple pores

info
***
Binding of the sperm to the zona pellucida (sperm-oocyte interactions) is a complex and critical event during fertilization.
***
Under LH influence they develop into a glandular structure, the corpus luteum – which secretes
***progesterone
(to help implantation)and some estrogen

These hormones, particularly progesterone, cause the endometrial glands to secrete and prepare the endometrium for implantation of the =
blastocyst
Structure of the pre ovalotory Follicle
Theca interna
Antrum
Oocyte
Structure of the ovalotory Follicle

slide 74
Ovarian stroma
Theca externa
Granulosa cells
theca interna
Antrum

ejected - Cumulus ophorus cells
Structure of the Corpus Luteum
Ovarian stroma
Luteal Cells
Blood vessels
Fibrin
corpus luteum of pregnancy remains functionally active throughout the first =
20 weeks
after ______? the placenta produces E / Prog.)
20 wks
***When pregnancy occurs, degeneration of the corpus luteum is prevented by =
H?
human chorionic gonadotropin (hCG)
human chorionic gonadotropin (hCG) is produced by
trophoblast cell from placenta
hCG, a hormone produced by the =
syncytiotrophoblast

info
hCG, a hormone produced by the syncytiotrophoblast keeps the corpus luteum secreting estrogens and progesterone

The luteal phase continues and menstruation does not occur.
Cleavage of the zygote and blastogenesis occur

The blastocyst begins to implant in the endometrium on about the =
sixth day of the luteal phase

(day 20 of a 28-day cycle)
If the oocyte is not fertilized:

the corpus luteum involutes and degenerates 10 to 12 days after ovulation

It is then called a corpus luteum of menstruation

The corpus luteum is subsequently transformed into white scar tissue in the ovary - a
corpus albicans
The corpus luteum degenerates

Estrogen and progesterone levels fall and the secretory endometrium enters an
ischemic phase

Menstruation occurs.