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31 Cards in this Set
- Front
- Back
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Truncus arteriosus becomes
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Ascending aorta and pulmonary trunk
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Bulbus cordis becomes
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Right ventricle
Smooth parts (outflow tract) of left and right ventricles |
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Primitive ventricle becomes
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Portion of left ventricle
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Primitive atria become
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Trabeculated left and right atria
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Left horn of sinus venosus becomes
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Coronary sinus
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Right horn of sinus venosus becomes
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Smooth part of right atrium
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Right common cardinal vein and right anterior cardinal vein become
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superior vena cava
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From what type of cells is the aorticopulmonary septum derived?
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neural crest cells --> migrate to divide truncus arteriosus into 2 arteries via fusion and twisting --> ascending aorta and pulmonary trun
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What pathology results from failure of the truncus arteriosus to twist?
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Transposition of the great arteries
Tetralogy of Fallot |
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What other defect is associated with a persistent truncus arteriosus?
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VSD
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Describe formation of the foramen ovale using the following terms:
endocardial cushion septum primum foramen primum foramen secundum septum secundum |
1. Foramen primum is large; Septum primum grows towards endocardial cushion
2. Foramen secundum forms above part of septum primum (there are 2 foramina) 3. Septum primum fuses with endocardial cushion; Septum secundum starts to grow into foramen secundum 4. Upper septum secundum degenerates and foramen ovale (foramen secundum) remains patent with septum primum below, secundum on top |
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What heart defects are associated with Down syndrome?
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Endocardial cushion defects (ASD)
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Where does erythropoiesis take place during the following times:
- Weeks 3-8 - Weeks 6-30 - Weeks 9-28 - Weeks 28+ |
- yolk sac
- liver - spleen - bone marrow (Young Liver Synthesizes Blood) |
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What is shunted through the ductus venosus?
What is bypassed? |
Oxygenated blood from the umbilical arteries to the IVC
Bypasses hepatic circulation |
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What is shunted through the foramen ovale?
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Most oxygenated blood from the IVC to the left heart/aorta
Bypasses pulmonary circulation |
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What is shunted through the ductus arteriosus?
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Deoxygenated blood from the SVC (some goes to pulmonary artery) to the lower body
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What happens upon taking first breath to the shunts?
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Decreased P in pulmonary arteries --> increased P in left atrium --> closure of foramen ovale
Increased oxygen causes decrease in prostaglandins --> closure of DA |
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What maintains a PDA?
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Prostaglandins (Misoprostil, Alprostadil)
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What closes a PDA?
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NSAIDs (Indomethacin)
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What is the postnatal derivative of the umbilical vein?
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ligamentum teres hepatis
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What is the postnatal derivative of the umbiLical arteries?
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mediaL umbilical ligaments
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What is the postnatal derivative of the ductus arteriosus?
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ligamentum arteriosum
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What is the postnatal derivative of the ductus venosus?
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ligamentum venosum
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What is the postnatal derivative of the foramen ovale?
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fossa ovalis
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What is the postnatal derivative of the allaNtois-urachus?
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mediaN umbilical ligament
May have urachal cyst/sinus |
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What is the postnatal derivative of the notocord?
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nucleus puposus of intervertebral disk
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What develops from the 1st aortic arch?
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part of MAXillary artery (branch of external carotid)
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What develops from 2nd aortic arch?
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Stapedial artery
hyoid artery Second Stapedial |
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What develops from 3rd aortic arch?
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Common Corotid
proximal internal Carotid C is 3rd letter |
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What develops from 4th aortic arch?
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On left: aortic arch
On right: proximal subclavian |
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What develops from 6th aortic arch?
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On left: ductus arteriosus
Proximal pulmonary arteries |
