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110 Cards in this Set

  • Front
  • Back
When does a post op MI usually occur?
Right after the surgery.
What are the risk factors for post op MI?
Pre op CHF
Ischemia on chemical or exercise stress test
Age >70yo
Signs of hypovolemia post op?
Restlessness
Anxious
Pale
Cool skin
Tachycardia
Orthostasis
How do you treat post op hypovolemia?
Fluid resuscitation (2L of crystalloid)- NS or LR

If that doesn't work give blood
*Don't give pressors
What is the MCC of LV failure and pulmonary edema?
Fluid overload and decreased cardiac reserve.
How do you treat post op LV cardiac and pulmonary edema?
Shock - ICU, preload and afterload tx

Stable - Dig, Fluid restriction and diuretics
What causes post op urinary retention?
Excessive catecholamine stimulation of alpha adrenergic receptors in smooth muscles of bladder neck and urethra
and
Excessive IV fluid admin
What are some characteristics of post op urinary retention?
Cramping
Urgency
Lower abd pain
Unable to void
How is post op urinary retention managed?
Do a bladder scan. Cath q 6-8hrs.

w/ BPH complications you might send home with a Foley and F/U c/urology.
When would an anastomotic leak usu. occur?
7-14d
How does an anastomotic leak usu. present and how do you manage it?
Usu. c/features of intraabd. abcess.

Return to OR and create colostomy.
What is the difference btwn an ileus and SBO?
Ileus - normal neurological control slows, non mechanical.
non- emergent

SBO- Mechanical block; can be emergent.
How is an ileus managed?
NG tube maybe to bring out acid that is produced.
Bowel rest.
Movement should stimulate return of normal bowel function.

Might get a film of abd.
How is an SBO managed?
Use NG suction for a couple of days.
Bowel rest.
Complete bowel obstruction - surgery.
Might get a film of abd.
If you obtain a film of the abd and you see gas in the rectum what does that let you know?
That something is getting through. If no gas was there you have a probable obstruction.
What are the first S/S of an anastomotic leak?
Fever, tachycardia
If a pt has persistent(chronic pain) at an operative site, what should you think about? How do you manage this?
Stitch abcess
Granuloma
Incision

Explore the area; May need to remove a stitch.
What is the most common psychiatric complication following surgery?
Delirium
Some causes of post op delirium?
Drugs
Drug combos
Metabolic disturbance
Hypoxia, sepsis
Alcohol/drug withdrawal
Due to the fact that you cannot prevent alcohol withdrawal post op what can help?
Benzos help sx.
How can you tx post op delirium agitation?
Haldol 2-25mg PO
What does the DT(Delirium Tremens) prodrome consist of?
Diaphoresis
Agitation
Hallucination
How do you prevent ICU psychosis?
Decreased noise
Adequate sleep
Remove from ICU asap
How do you treat DTs?
Alcohol or benzos
Replace vit B and Mg
Breakdown of body fluid by compartment?
Intracellular (most)

Extracellular
a) Interstitial (more than below)
b)Intravascular
What is ICF made up of?
Potassium
Organic phosphate
Sulfate
What is ECF made up of?
Sodium
Chloride
Bicarbonate
What is an important propterty of the intravascular compartment as far as proteins are concerned?
The intravascular compartment contains more Albumin which gives plasma its high colloid osmotic pressure (pulls water in).
What are the daily maintenance fluid requirements for adults (with normal renal function)?
Water 2-2.5L/day
Sodium 75meq/day
K+ 40-60meq/day
Glucose 100Gm/day
Important limitations of maintenance fluid therapy?
Doesn't provide adequate calories
No AA, Fatty acids, or vital micronutrients
Cannot be sustained longer than 3-5days
What is a crystalloid sol'n and what are the types?
Aqueous soln of low molecular wt ions: salts

Isotonic: 260-340mOsm
Hypotonic: <260
Hypertonic: >340

Normal serum is 285-295
What are the types of isotonic replacement fluids?
Considered replacement fluid bc same osmo as blood so stays in pipe.

NS and LR
What are the tonicity, components, and special considerations with normal saline and LR solns?
NS: Ton: 308;
Na, Cl (both 154)

LR: Ton:273
Na,Cl,K+,Ca2+,Lactate

Expand IV compartment
Monitor for overload (esp HTN, CHF)
Avoid in pts with liver dz or alkalosis- choose NS over LR
Which IV soln most closely approximates serum?
LR
Which IV solns are considered hypotonic?
Maintenance fluids

Will move interstitially rather than intracellularly.

1/2NS and D5W
What are the tonicity, components, and special considerations with 1/2NS and D5W solns?
1/2NS: Ton: 154;
Na,Cl(both 77)

D5W-5% dextrose in water: Ton: 253
Glucose only

Causes fluid shift intracellularly
Caution c/ increased ICP
Avoid in pts at risk for fluid shifts(burns, trauma, low protein states)
Which IV solns are considered hypertonic?
D5 1/2 NS, D5 1/4NS (peds)
D5NS
D5LR
What are the tonicity, components, and special considerations with D5 1/2NS, D5 1/4NS (peds), D5NS, D5LR solns?
D5 1/2 NS, D5 1/4NS(Ton355) (peds):
Ton: 432
Na, Cl, glucose

D5NS:Ton(586)
Na, Cl, glucose

D5LR: Ton(525)
Na, CL, K+, Ca2+, Glucose,Lactate

Will pull H20 into intravascular space.
Use to expand volume (IV compartment).
Avoid in DKA pts with cellular dehydration.
Caution in pts c/ impaired kidney function or heart fxn.
What is the most common IV fluid given to a pt?
D5 1/2 NS
What do all of the hypertonic solutions contain?
Dextrose - sugar.
What are some clinical manifestations of volume depletion?
Tachycardia
Low BP-1st orthostatic HTN
Narrow pulse pressure
Poor skin turgor
Dry mucous membranes

I&O, body weight
In what conditions would you find volume depletion only (no solute deficit)?
Pts who cannot regulate intake:
Debilitated
Comatose
Insensible loss from fever

Pts on tube feeds c/o H20 supplementation and or with DI
What type of hyponatremia would be caused by pure water deficit?
Hypotonic hypernatremia

Clinical findings:
Increased plasma osmo
Concentrated urine
Low urine sodium

Bc of increased serum sodium:
Muscle rigidity, Tremors, CNS(lethargy or coma)
How do you treat hypotonic hypernatremia due to volume depletion?
Replace H20 to restore sodium to normal.

Hypotonic, maintenance type fluid. D5W or 1/2NS
In what pts is volume and electrolyte deficiency commonly seen?

What are the clinical findings?
Surgical

Similar to pure volume depletion.
Urine Na<10meq/L
Concentrated urine
Serum chem consistent c/ prerenal azotemia-->
BUN/Cr >20:1
Why would you not want to give a patient with alkalosis an IV soln with lactate in it?
Because the lactate is broken down in the liver and converted to bicarbonate which makes alkalosis worse.

LR and D5LR
When a pt has volume and electrolyte depletion what type of fluid would you want to give?
Isotonic, "Replacement"

If plasma Na+ is normal:
LR

NS(may cause hyperchloremic acidosis bc plasma bicarb concentration decreases as chloride concentration increases)
What type of condition is NS more useful in?
Hypochloremic metabolic acidosis
PRBC infusion
Why is dextrose added to IV fluid?
To prevent ketosis or hypoglycemia due to fasting.

Women and children more likely.
Why does post op volume overload occur?
Excessive volume in peri operative period when aldosterone and ADH are secreted. (exaggerated with heart failure, renal or liver dz, hypoalbuminemia).
Clinical manifestations of volume overload? How do you treat this?
Edema, JVD, Tachypnea, Increased body weight, Increased CVP

Tx= H20 restriction, give hypotonic solution like 1/2 NS
What are colloid solutions?

When are they indicated?
Higher osmo's

Contain complex sugar or protein to maintain colloid osmotic presssure gradient.

Indicated=
Severe intravascular fluid deficits(hemorrhagic shock) prior to blood transfusion.
Severe hypoalbuminemia or conditions with large proteins losses (burns)
How is a burn handled as far as IV fluids go? *LR or NS
Crystalloid for 1st 24 hours then colloid once leaky capillaries close.
3 types of colloid solns?
Albumin(blood derived)

synthetic:
Dextran
Hetastarch
How are maintenance fluids calculated?
First 10kg:100ml/kg/d
Second 10kg:50ml/kg/d
Rest of weight:20ml/kg/d

Add up and thats your mL of H20 per day. Divide by 24 to get rate per hour.
When adjusting IV fluid for Fluid/Electrolyte losses how do you adjust for fever?
Add more
Every 1 degree over 100F, add 2cc/kg/d
When adjusting IV fluid for Fluid/Electrolyte losses how do you adjust for vomiting, diarrhea, blood loss, 3rd spacing?
Just replace what is lost.
What IV fluid order is given for Gastric loss(NG tube, emesis)?
D5 1/2 NS with 20mEq KCL
What IV fluid order is given for Diarrhea?
Losing bicarb

D5LR with 15 meq/L KCl. 1L for each 1kg or 2.2lbs lost.

Less KCl here than vomiting because LR has some K+.
What IV fluid order is given for Pancreatic loss?
D5LR with 50meq/L, 1amp HCO3
Roughly the max of K+ that can be given without being in the ICU and doing an EKG?
20meq
Generally what type of fluid is a bolus?
Maintenance fluid.

Just open up line and let it drip in as fast as it will.
What, metabolically happens, 12 hrs NPO?
Plasma insulin starts to fall
Glucagon output increases
Hepatic glycogen is converted to glucose.
What, metabolically happens, 24 hrs NPO?
What can prevent muscle breakdown in short term fasting?
Hepatic gluconeogenesis using AAs occurs with peak loss.
AAs are converted to ketones to run on.

Replacement of exogenous glucose per day. (100g/d)
What, metabolically happens, with prolonged NPO status(days)?
Fat is broken down to glycerol and fatty acids.

Adaptive ketogenesis - liver produces ketone bodies. Brain can become accustomed to ketone bodies instead of glucose.
When is a status of baseline malnutrition defined?
>10% wt loss in 3months

Norm albumin >3
Can check prealbumin first (normal about 20)
How can you calculate nutritional requirements?
BEE (Basal energy expenditure requirements)

Males:
66.4 + [13.7 x wt(kg)] +
[5 x height(cm)] - [6.8 x age]

Females:
665 + [9.6 x wt(kg)] +
[1.7 x height(cm)] - [4.7 x age]
How is BEE affected with no post op complications?
Normal
How is BEE affected with mild peritonitis, long bone fx, moderate injury?
25% above normal
How is BEE affected with severe injury?
50% above normal
How is BEE affected with Burns of 40-100% TBS?
100% above normal.
Typical daily nutritional requirements?
Carbs = min. of 400kcal/day
Protein= 0.8g/kg over 24hrs (60-70g/d)
Lipids
Difference btwn enteral and parenteral feeding?
Enteral - Still feeding through gut; by tube- NG, feeding, gastric, or jejun.

Parenteral = Via vein (peripheral or central)
What would be 2 indications for enteral feeding?
Malnourished pts with intact GI tract.

Pts unable to meet 2/3-3/4 of daily needs.
What are some contraindications to enteral feeding?
Short bowel
GI obstruction or bleeding
Protracted vomiting/diarrhea
Ileus
Active GI ischemia requiring bowel rest.
A risk of NG tube use?
Nocosomia pneumonia
Nasal ischemia

This is short term.
Who would an 'elemental' feeding formula be good for?
If the pt cannot tolerate high osmo; proteins are already broken into amino acids.
Who would a 'modular' feeding formula be good for?
Renal or hepatic failure
What are gastric residual volumes?
A way to monitor tube feeding. Is the feeding being absorbed or just sitting there.

>200cc hold feeding then restart.
Technical vs functional complications of enteral feeding?
Technical - clogging of tube
Functional - dont tolerate formula.
Peripheral Parenteral Nutrition?
Lower osmo than TPN. Delivered by IV or PICC line. Subclavian line- can give higher sugar load.
Total parenteral nutrition?
For pts who cannot obtain adequate nourishment from GI tract. Minimum 7-10d.

3:1 mixture
Protein(AA)
Carb(Dextrose)
Fat (Soybean/safflower oil)
Vitamins and trace elements.
Complications of PPN vs TPN?
Technical and infectious.

TPN: Metabolic.
What is the first phase of wound healing?
1) Inflammatory:1-2d
Cytokines brought to area
Attracts platelets and leukocytes (NEUTROPHILS first)
These eat debris and put out IL-1
Fibroblasts attracted which lay and secrete collagen network.
What is the second phase of wound healing?
Proliferative phase - 48-72h
Fibroblasts continue to lay collagen over 6wks. Angiogeneisis too. Reform capillary network.

Contact inhibition - stops scarring. If this is absent you get keloids.
What is the third phase of wound healing?
Remodeling phase - wks-months
collagen crosslinks added for strength
At 6 wks how strong is your wound?
Should be 70-80% tensile strength.
What are some factors that affect wound healing?
Infection
Time
Hematoma
Necrotic tissue
Necrotic tissue
Pts health status
Meds

Blood supply
Mech of injury
Type of tissue injured
Technique
3 types of wound healing?
Primary intention
Secondary intention
Tertiary intention
What is primary intention?
Side to side & connect;
Most surgeries closed this way
Pretty wound outcome.
What is secondary intention?
Wound closes from middle
Expl: avulsion injury

Just cannot pull it together.
Use wet to dry dressings.
Indicated for a contaminated wound.
What is tertiary intention?
Delayed primary closure
Secondary then close side to side.

Expl: Perforated appendix.Waiting for removal of infectious source.
What is the usual pre-op antibiotic?
Anceph - C1
Usu g (+) coverage.
Surface bacteria staph and strep.
Classification of wounds?(4)
Risk of post op infection?
Clean(2%) - <6wks
doesnt involve violation of hollow viscus. mole,SCC

Clean-contaminated(10%)
Viscus purposefully/accidentally violated with minimal spillage. Small bowel or prepped large bowel.

Contaminated(20%) - excessive spillage or inflammation or where bacterial count is excessive. appendectomy.

Dirty(60%)- Colon perf.
What does classification of wounds help with?
Antibiotic ordering.
What type of antibotic coverage is needed for a clean wound?
Staph Aureus, Staph epidermis

None given or 1st gen ceph
What type of antibotic coverage is needed for a clean-contaminated wound?
Enterobacteriaceae, Enterococci, Anerobes

2nd gen ceph (Cephoxitan, Cefotetan)

Anaerobic coverage - metronidazol, clindamycin
What type of antibotic coverage is needed for a contaminated wound?
Similar to clean contaminated but larger number of bacteria.

Same as for clean contam. preop and post op regimen too.
What type of antibotic coverage is needed for a dirty wound?
Gross contamination with g+, g-, and anaerobes.

pre-op, post op, and prolonged antibiotic course.
Trauma victim with major wound. First important step?
Still ABCs
What are motor and sensory checks for L4 nerve root?
Sensory - medial side of foot
Motor - Foot inversion or dorsiflexion
What are motor and sensory checks for L5 nerve root?
Sensory - dorsum of foot
Motor - Toe extension(up)
What are motor and sensory checks for S1 nerve root?
Sensory: Lateral foot
Motor: Eversion
What are motor and sensory checks for radial nerve?
Sensory: Index finger -on top of hand
Motor:Extension of fingers, wrist ext/dorsiflex
What are motor and sensory checks for ulnar nerve?
Sensory: pinky
Motor: Fanning (ab/ad of fingers)
What are motor and sensory checks for Median nerve?
Sensory: 1st web space
Motor: Thumb flexion and opposition
With a wound what important shot should be noted?
last tetanus

every 10 years unless incident then every 5
What would an xray not pick up, as far as foreign bodies go?
Wood, fish bone, some cactus spines.
Classification of a tetanus prone wound?
Age
Configuration
Depth
Mechanism of injury
Signs of infxn
Devitalized tissue
Ischemia/denervate
Contaminants
>6hrs
Stellate, avulsion
>1cm
Missile,crush,burn, frostbite

Present:
Signs of infxn
Devitalized tissue
Ischemia/denervate
Contaminants
Classification of a non-tetanus prone wound?
Age
Configuration
Depth
Mechanism of injury
Signs of infxn
Devitalized tissue
Ischemia/denervate
Contaminants
<6hrs
Linear, abrasion
<1cm
Sharp surface

Absent:
Signs of infxn
Devitalized tissue
Ischemia/denervate
Contaminants